-
1
-
-
84863562673
-
Glioblastoma survival in the United States before and during the temozolomide era
-
PMID: 22045118
-
Johnson DR, O'Neill BP (2011) Glioblastoma survival in the United States before and during the temozolomide era. J Neurooncol 107: 359-364. doi: 10.1007/s11060-011-0749-4 PMID: 22045118
-
(2011)
J Neurooncol
, vol.107
, pp. 359-364
-
-
Johnson, D.R.1
O'Neill, B.P.2
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
PMID: 15758009
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996. PMID: 15758009
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
3
-
-
77951599543
-
Targeting brain cancer: Advances in the molecular pathology of malignant glioma and medulloblastoma
-
PMID: 20414201
-
Huse JT, Holland EC (2010) Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10: 319-331. doi: 10.1038/nrc2818 PMID: 20414201
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 319-331
-
-
Huse, J.T.1
Holland, E.C.2
-
4
-
-
1542682591
-
Glioma invasion - Pattern of dissemination by mechanisms of invasion and surgical intervention, pattern of gene expression and its regulatory control by tumorsuppressor p53 and protooncogene ETS-1
-
PMID: 14531573
-
Giese A (2003) Glioma invasion - pattern of dissemination by mechanisms of invasion and surgical intervention, pattern of gene expression and its regulatory control by tumorsuppressor p53 and protooncogene ETS-1. Acta Neurochir Suppl 88: 153-162. PMID: 14531573
-
(2003)
Acta Neurochir Suppl
, vol.88
, pp. 153-162
-
-
Giese, A.1
-
5
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
PMID: 22137795
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, et al. (2011) Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 20: 810-817. doi: 10.1016/j.ccr.2011.11.005 PMID: 22137795
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
Davidson, C.J.6
-
6
-
-
83455171954
-
Many tumors in one: A daunting therapeutic prospect
-
PMID: 22172718
-
Ene CI, Fine HA (2011) Many tumors in one: a daunting therapeutic prospect. Cancer Cell 20: 695-697. doi: 10.1016/j.ccr.2011.11.018 PMID: 22172718
-
(2011)
Cancer Cell
, vol.20
, pp. 695-697
-
-
Ene, C.I.1
Fine, H.A.2
-
7
-
-
84895421055
-
Killing me softly-future challenges in apoptosis research
-
PMID: 24595238
-
Westhoff MA, Bruhl O, Nonnenmacher L, Karpel-Massler G, Debatin KM (2014) Killing me softly-future challenges in apoptosis research. Int J Mol Sci 15: 3746-3767. doi: 10.3390/ijms15033746 PMID: 24595238
-
(2014)
Int J Mol Sci
, vol.15
, pp. 3746-3767
-
-
Westhoff, M.A.1
Bruhl, O.2
Nonnenmacher, L.3
Karpel-Massler, G.4
Debatin, K.M.5
-
8
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
PMID: 18772890
-
Network TCGAR (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068. doi: 10.1038/nature07385 PMID: 18772890
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Network TCGAR1
-
9
-
-
79952111297
-
Targeting the RTK-PI3K-mTOR axis in malignant glioma: Overcoming resistance
-
PMID: 20535652
-
Fan QW, Weiss WA (2010) Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance. Curr Top Microbiol Immunol 347: 279-296. doi: 10.1007/82-2010-67 PMID: 20535652
-
(2010)
Curr Top Microbiol Immunol
, vol.347
, pp. 279-296
-
-
Fan, Q.W.1
Weiss, W.A.2
-
10
-
-
84878831559
-
Overcoming acquired resistance to anticancer therapy: Focus on the PI3K/AKT/mTOR pathway
-
PMID: 23377372
-
rd (2013) Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway. Cancer Chemother Pharmacol 71: 829-842. doi: 10.1007/s00280-012-2043-3 PMID: 23377372
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 829-842
-
-
Burris, H.A.1
-
11
-
-
84897019565
-
Glioblastoma: From molecular pathology to targeted treatment
-
PMID: 23937436
-
Cloughesy TF, Cavenee WK, Mischel PS (2013) Glioblastoma: from molecular pathology to targeted treatment. Annu Rev Pathol 9: 1-25. doi: 10.1146/annurev-pathol-011110-130324 PMID: 23937436
-
(2013)
Annu Rev Pathol
, vol.9
, pp. 1-25
-
-
Cloughesy, T.F.1
Cavenee, W.K.2
Mischel, P.S.3
-
12
-
-
84900809700
-
Efficacy of rapamycin against glioblastoma cancer stem cells
-
PMID: 24043497
-
Mendiburu-Elicabe M, Gil-Ranedo J, Izquierdo M (2014) Efficacy of rapamycin against glioblastoma cancer stem cells. Clin Transl Oncol 16: 495-502. doi: 10.1007/s12094-013-1109-y PMID: 24043497
-
(2014)
Clin Transl Oncol
, vol.16
, pp. 495-502
-
-
Mendiburu-Elicabe, M.1
Gil-Ranedo, J.2
Izquierdo, M.3
-
13
-
-
78149479091
-
mTOR signaling in glioblastoma: Lessons learned from bench to bedside
-
PMID: 20472883
-
Akhavan D, Cloughesy TF, Mischel PS (2010) mTOR signaling in glioblastoma: lessons learned from bench to bedside. Neuro Oncol 12: 882-889. doi: 10.1093/neuonc/noq052 PMID: 20472883
-
(2010)
Neuro Oncol
, vol.12
, pp. 882-889
-
-
Akhavan, D.1
Cloughesy, T.F.2
Mischel, P.S.3
-
14
-
-
51049112961
-
Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis
-
PMID: 18676851
-
Opel D, Westhoff MA, Bender A, Braun V, Debatin KM, Fulda S (2008) Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis. Cancer Res 68: 6271-6280. doi: 10.1158/0008-5472.CAN-07-6769 PMID: 18676851
-
(2008)
Cancer Res
, vol.68
, pp. 6271-6280
-
-
Opel, D.1
Westhoff, M.A.2
Bender, A.3
Braun, V.4
Debatin, K.M.5
Fulda, S.6
-
15
-
-
70349974841
-
The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair
-
PMID: 19633683
-
Westhoff MA, Kandenwein JA, Karl S, Vellanki SH, Braun V, Eramo A, et al. (2009) The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair. Oncogene 28: 3586-3596. doi: 10.1038/onc.2009.215 PMID: 19633683
-
(2009)
Oncogene
, vol.28
, pp. 3586-3596
-
-
Westhoff, M.A.1
Kandenwein, J.A.2
Karl, S.3
Vellanki, S.H.4
Braun, V.5
Eramo, A.6
-
16
-
-
84896691989
-
Sequential Dosing in Chemosensitization: Targeting the PI3K/Akt/mTOR Pathway in Neuroblastoma
-
PMID: 24391739
-
Westhoff MA, Faham N, Marx D, Nonnenmacher L, Jennewein C, Enzenmuller S, et al. (2013) Sequential Dosing in Chemosensitization: Targeting the PI3K/Akt/mTOR Pathway in Neuroblastoma. PLoS One 8: e83128. doi: 10.1371/journal.pone.0083128 PMID: 24391739
-
(2013)
PLoS One
, vol.8
-
-
Westhoff, M.A.1
Faham, N.2
Marx, D.3
Nonnenmacher, L.4
Jennewein, C.5
Enzenmuller, S.6
-
17
-
-
84873891025
-
GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death
-
Enzenmuller S, Gonzalez P, Karpel-Massler G, Debatin KM, Fulda S (2012) GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death. Cancer Lett.
-
(2012)
Cancer Lett
-
-
Enzenmuller, S.1
Gonzalez, P.2
Karpel-Massler, G.3
Debatin, K.M.4
Fulda, S.5
-
18
-
-
84875762286
-
Radiosensitization of Glioblastoma Cell Lines by the Dual PI3K and mTOR Inhibitor NVP-BEZ235 Depends on Drug-Irradiation Schedule
-
PMID: 23544169
-
Kuger S, Graus D, Brendtke R, Gunther N, Katzer A, Lutyj P, et al. (2013) Radiosensitization of Glioblastoma Cell Lines by the Dual PI3K and mTOR Inhibitor NVP-BEZ235 Depends on Drug-Irradiation Schedule. Transl Oncol 6: 169-179. PMID: 23544169
-
(2013)
Transl Oncol
, vol.6
, pp. 169-179
-
-
Kuger, S.1
Graus, D.2
Brendtke, R.3
Gunther, N.4
Katzer, A.5
Lutyj, P.6
-
19
-
-
84895807281
-
Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma
-
PMID: 24366691
-
Gil del Alcazar CR, Hardebeck MC, Mukherjee B, Tomimatsu N, Gao X, Yan J, et al. (2014) Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma. Clin Cancer Res 20: 1235-1248. doi: 10.1158/1078-0432.CCR-13-1607 PMID: 24366691
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1235-1248
-
-
Gil Del Alcazar, C.R.1
Hardebeck, M.C.2
Mukherjee, B.3
Tomimatsu, N.4
Gao, X.5
Yan, J.6
-
20
-
-
84892380757
-
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: Targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases
-
PMID: 24418474
-
Choi EJ, Cho BJ, Lee DJ, Hwang YH, Chun SH, Kim HH, et al. (2014) Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases. BMC Cancer 14: 17. doi: 10.1186/1471-2407-14-17 PMID: 24418474
-
(2014)
BMC Cancer
, vol.14
, pp. 17
-
-
Choi, E.J.1
Cho, B.J.2
Lee, D.J.3
Hwang, Y.H.4
Chun, S.H.5
Kim, H.H.6
-
21
-
-
84918817033
-
RIST: A potent new combination therapy for glioblastoma
-
PMID: 25123598
-
Nonnenmacher L, Westhoff MA, Fulda S, Karpel-Massler G, Halatsch ME, Engelke J, et al. (2015) RIST: A potent new combination therapy for glioblastoma. Int J Cancer 136: E173-187. doi: 10.1002/ijc.29138 PMID: 25123598
-
(2015)
Int J Cancer
, vol.136
, pp. E173-E187
-
-
Nonnenmacher, L.1
Westhoff, M.A.2
Fulda, S.3
Karpel-Massler, G.4
Halatsch, M.E.5
Engelke, J.6
-
22
-
-
41149163821
-
The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids
-
PMID: 17934519
-
De Witt Hamer PC, Van Tilborg AA, Eijk PP, Sminia P, Troost D, Van Noorden CJ, et al. (2008) The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids. Oncogene 27: 2091-2096. PMID: 17934519
-
(2008)
Oncogene
, vol.27
, pp. 2091-2096
-
-
De Witt Hamer, P.C.1
Van Tilborg, A.A.2
Eijk, P.P.3
Sminia, P.4
Troost, D.5
Van Noorden, C.J.6
-
23
-
-
84893448747
-
Artesunate Enhances the Antiproliferative Effect of Temozolomide on U87MG and A172 Glioblastoma Cell Lines
-
PMID: 24506460
-
Karpel-Massler G, Westhoff MA, Kast RE, Dwucet A, Nonnenmacher L, Wirtz CR, et al. (2014) Artesunate Enhances the Antiproliferative Effect of Temozolomide on U87MG and A172 Glioblastoma Cell Lines. Anticancer Agents Med Chem 14: 313-318. PMID: 24506460
-
(2014)
Anticancer Agents Med Chem
, vol.14
, pp. 313-318
-
-
Karpel-Massler, G.1
Westhoff, M.A.2
Kast, R.E.3
Dwucet, A.4
Nonnenmacher, L.5
Wirtz, C.R.6
-
24
-
-
51349083548
-
Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells
-
PMID: 18469856
-
Westhoff MA, Zhou S, Bachem MG, Debatin KM, Fulda S (2008) Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells. Oncogene 27: 5169-5181. doi: 10.1038/onc.2008.148 PMID: 18469856
-
(2008)
Oncogene
, vol.27
, pp. 5169-5181
-
-
Westhoff, M.A.1
Zhou, S.2
Bachem, M.G.3
Debatin, K.M.4
Fulda, S.5
-
25
-
-
4444338326
-
SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling
-
PMID: 15340073
-
Westhoff MA, Serrels B, Fincham VJ, Frame MC, Carragher NO (2004) SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling. Mol Cell Biol 24: 8113-8133. PMID: 15340073
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8113-8133
-
-
Westhoff, M.A.1
Serrels, B.2
Fincham, V.J.3
Frame, M.C.4
Carragher, N.O.5
-
26
-
-
51649088622
-
PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML
-
PMID: 18548104
-
Park S, Chapuis N, Bardet V, Tamburini J, Gallay N, Willems L, et al. (2008) PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML.Leukemia 22: 1698-1706. doi: 10.1038/leu.2008.144 PMID: 18548104
-
(2008)
Leukemia
, vol.22
, pp. 1698-1706
-
-
Park, S.1
Chapuis, N.2
Bardet, V.3
Tamburini, J.4
Gallay, N.5
Willems, L.6
-
27
-
-
67649534502
-
A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells
-
PMID: 19513541
-
Zou ZQ, Zhang XH, Wang F, Shen QJ, Xu J, Zhang LN, et al. (2009) A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. Int J Mol Med 24: 97-101. PMID: 19513541
-
(2009)
Int J Mol Med
, vol.24
, pp. 97-101
-
-
Zou, Z.Q.1
Zhang, X.H.2
Wang, F.3
Shen, Q.J.4
Xu, J.5
Zhang, L.N.6
-
28
-
-
78651385352
-
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models
-
PMID: 21084267
-
Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K (2011) A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models. Cancer Res 71: 154-163. doi: 10.1158/0008-5472.CAN-10-1601 PMID: 21084267
-
(2011)
Cancer Res
, vol.71
, pp. 154-163
-
-
Bagci-Onder, T.1
Wakimoto, H.2
Anderegg, M.3
Cameron, C.4
Shah, K.5
-
29
-
-
0022359131
-
Antitumour imidazotetrazines - XI: Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one [CCRG 81045; M and B 39831 NSC 362856] on poly(ADP-ribose) metabolism
-
PMID: 3864485
-
Tisdale MJ (1985) Antitumour imidazotetrazines - XI: Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one [CCRG 81045; M and B 39831 NSC 362856] on poly(ADP-ribose) metabolism. Br J Cancer 52: 789-792. PMID: 3864485
-
(1985)
Br J Cancer
, vol.52
, pp. 789-792
-
-
Tisdale, M.J.1
-
30
-
-
0030883212
-
Clinical pharmacokinetics of irinotecan
-
PMID: 9342501
-
Chabot GG (1997) Clinical pharmacokinetics of irinotecan. Clin Pharmacokinet 33: 245-259. PMID: 9342501
-
(1997)
Clin Pharmacokinet
, vol.33
, pp. 245-259
-
-
Chabot, G.G.1
-
31
-
-
50849086732
-
DNA repair and cancer stem-like cells - Potential partners in glioma drug resistance?
-
PMID: 18501520
-
Johannessen TC, Bjerkvig R, Tysnes BB (2008) DNA repair and cancer stem-like cells - potential partners in glioma drug resistance? Cancer Treat Rev 34: 558-567. doi: 10.1016/j.ctrv.2008.03.125 PMID: 18501520
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 558-567
-
-
Johannessen, T.C.1
Bjerkvig, R.2
Tysnes, B.B.3
-
32
-
-
65449126350
-
Present and potential future adjuvant issues in high-grade astrocytic glioma treatment
-
PMID: 19368079
-
Lefranc F, Rynkowski M, DeWitte O, Kiss R (2009) Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. Adv Tech Stand Neurosurg 34: 3-35. PMID: 19368079
-
(2009)
Adv Tech Stand Neurosurg
, vol.34
, pp. 3-35
-
-
Lefranc, F.1
Rynkowski, M.2
DeWitte, O.3
Kiss, R.4
-
33
-
-
84863594749
-
Sensitivity of glioblastomas to clinically available MEK inhibitors is defined by neurofibromin 1 deficiency
-
PMID: 22573716
-
See WL, Tan IL, Mukherjee J, Nicolaides T, Pieper RO (2012) Sensitivity of glioblastomas to clinically available MEK inhibitors is defined by neurofibromin 1 deficiency. Cancer Res 72: 3350-3359. doi: 10.1158/0008-5472.CAN-12-0334 PMID: 22573716
-
(2012)
Cancer Res
, vol.72
, pp. 3350-3359
-
-
See, W.L.1
Tan, I.L.2
Mukherjee, J.3
Nicolaides, T.4
Pieper, R.O.5
-
34
-
-
84879666141
-
ERK and PI3K signaling cascades induce Nrf2 activation and regulate cell viability partly through Nrf2 in human glioblastoma cells
-
PMID: 23708697
-
Cong ZX, Wang HD, Wang JW, Zhou Y, Pan H, Zhang DD, et al. (2013) ERK and PI3K signaling cascades induce Nrf2 activation and regulate cell viability partly through Nrf2 in human glioblastoma cells. Oncol Rep 30: 715-722. doi: 10.3892/or.2013.2485 PMID: 23708697
-
(2013)
Oncol Rep
, vol.30
, pp. 715-722
-
-
Cong, Z.X.1
Wang, H.D.2
Wang, J.W.3
Zhou, Y.4
Pan, H.5
Zhang, D.D.6
-
35
-
-
84899099255
-
miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways
-
PMID: 24603851
-
Liu Z, Jiang Z, Huang J, Huang S, Li Y, Yu S, et al. (2014) miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways. Int J Oncol 44: 1571-1580. doi: 10.3892/ijo.2014.2322 PMID: 24603851
-
(2014)
Int J Oncol
, vol.44
, pp. 1571-1580
-
-
Liu, Z.1
Jiang, Z.2
Huang, J.3
Huang, S.4
Li, Y.5
Yu, S.6
-
36
-
-
84922391490
-
MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathways
-
PMID: 24736727
-
Yao Y, Xue Y, Ma J, Shang C, Wang P, Liu L, et al. (2014) MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathways. PLoS One 9: e95060. doi: 10.1371/journal.pone.0095060 PMID: 24736727
-
(2014)
PLoS One
, vol.9
-
-
Yao, Y.1
Xue, Y.2
Ma, J.3
Shang, C.4
Wang, P.5
Liu, L.6
-
37
-
-
33645472347
-
Combined inhibition of the phosphatidylinositol 3-kinase/Akt and Ras/mitogen-activated protein kinase pathways results in synergistic effects in glioblastoma cells
-
PMID: 16546979
-
Edwards LA, Verreault M, Thiessen B, Dragowska WH, Hu Y, Yeung JH, et al. (2006) Combined inhibition of the phosphatidylinositol 3-kinase/Akt and Ras/mitogen-activated protein kinase pathways results in synergistic effects in glioblastoma cells. Mol Cancer Ther 5: 645-654. PMID: 16546979
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 645-654
-
-
Edwards, L.A.1
Verreault, M.2
Thiessen, B.3
Dragowska, W.H.4
Hu, Y.5
Yeung, J.H.6
-
38
-
-
84885032145
-
MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling
-
PMID: 24124570
-
Evans C, Cook SJ, Coleman MP, Gilley J (2013) MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS One 8: e76505. doi: 10.1371/journal.pone.0076505 PMID: 24124570
-
(2013)
PLoS One
, vol.8
-
-
Evans, C.1
Cook, S.J.2
Coleman, M.P.3
Gilley, J.4
-
39
-
-
84900312351
-
Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA
-
PMID: 24489888
-
Chen D, Zuo D, Luan C, Liu M, Na M, Ran L, et al. (2014) Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA. PLoS One 9: e87281. doi: 10.1371/journal.pone.0087281 PMID: 24489888
-
(2014)
PLoS One
, vol.9
-
-
Chen, D.1
Zuo, D.2
Luan, C.3
Liu, M.4
Na, M.5
Ran, L.6
-
40
-
-
0041924982
-
A novel role for FAK as a protease-targeting adaptor protein: Regulation by p42 ERK and Src
-
PMID: 12932330
-
Carragher NO, Westhoff MA, Fincham VJ, Schaller MD, Frame MC (2003) A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src. Curr Biol 13: 1442-1450. PMID: 12932330
-
(2003)
Curr Biol
, vol.13
, pp. 1442-1450
-
-
Carragher, N.O.1
Westhoff, M.A.2
Fincham, V.J.3
Schaller, M.D.4
Frame, M.C.5
-
41
-
-
80052020964
-
FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity
-
PMID: 21793107
-
Sunayama J, Sato A, Matsuda K, Tachibana K, Watanabe E, Seino S, et al. (2011) FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity. Stem Cells 29: 1327-1337. doi: 10.1002/stem.696 PMID: 21793107
-
(2011)
Stem Cells
, vol.29
, pp. 1327-1337
-
-
Sunayama, J.1
Sato, A.2
Matsuda, K.3
Tachibana, K.4
Watanabe, E.5
Seino, S.6
-
42
-
-
84884346038
-
PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1
-
PMID: 23907540
-
Gont A, Hanson JE, Lavictoire SJ, Parolin DA, Daneshmand M, Restall IJ, et al. (2013) PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1. Oncotarget 4: 1266-1279. PMID: 23907540
-
(2013)
Oncotarget
, vol.4
, pp. 1266-1279
-
-
Gont, A.1
Hanson, J.E.2
Lavictoire, S.J.3
Parolin, D.A.4
Daneshmand, M.5
Restall, I.J.6
-
43
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
PMID: 22439924
-
Magee JA, Piskounova E, Morrison SJ (2012) Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 21: 283-296. doi: 10.1016/j.ccr.2012.03.003 PMID: 22439924
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
44
-
-
84898916430
-
Cells isolated from human glioblastoma multiforme express progesterone-induced blocking factor (PIBF)
-
PMID: 24474429
-
Kyurkchiev D, Naydenov E, Tumangelova-Yuzeir K, Ivanova-Todorova E, Belemezova K, Bochev I, et al. (2014) Cells isolated from human glioblastoma multiforme express progesterone-induced blocking factor (PIBF). Cell Mol Neurobiol 34: 479-489. doi: 10.1007/s10571-014-0031-3 PMID: 24474429
-
(2014)
Cell Mol Neurobiol
, vol.34
, pp. 479-489
-
-
Kyurkchiev, D.1
Naydenov, E.2
Tumangelova-Yuzeir, K.3
Ivanova-Todorova, E.4
Belemezova, K.5
Bochev, I.6
-
45
-
-
72449210651
-
Cancer stem cells: Cell culture, markers, and targets for new therapies
-
PMID: 19760641
-
Gilbert CA, Ross AH (2009) Cancer stem cells: cell culture, markers, and targets for new therapies. J Cell Biochem 108: 1031-1038. doi: 10.1002/jcb.22350 PMID: 19760641
-
(2009)
J Cell Biochem
, vol.108
, pp. 1031-1038
-
-
Gilbert, C.A.1
Ross, A.H.2
-
46
-
-
33846876273
-
Targeting brain-tumor stem cells
-
PMID: 17287755
-
Stupp R, Hegi ME (2007) Targeting brain-tumor stem cells. Nat Biotechnol 25: 193-194. PMID: 17287755
-
(2007)
Nat Biotechnol
, vol.25
, pp. 193-194
-
-
Stupp, R.1
Hegi, M.E.2
-
47
-
-
84855405497
-
The proliferation rate paradox in antimitotic chemotherapy
-
PMID: 22210845
-
Mitchison TJ (2012) The proliferation rate paradox in antimitotic chemotherapy. Mol Biol Cell 23: 1-6. doi: 10.1091/mbc.E10-04-0335 PMID: 22210845
-
(2012)
Mol Biol Cell
, vol.23
, pp. 1-6
-
-
Mitchison, T.J.1
-
48
-
-
33644859147
-
Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma
-
PMID: 16412023
-
Georgakis GV, Li Y, Rassidakis GZ, Medeiros LJ, Mills GB, Younes A (2006) Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma. Br J Haematol 132: 503-511 PMID: 16412023
-
(2006)
Br J Haematol
, vol.132
, pp. 503-511
-
-
Georgakis, G.V.1
Li, Y.2
Rassidakis, G.Z.3
Medeiros, L.J.4
Mills, G.B.5
Younes, A.6
-
49
-
-
40749111022
-
Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas
-
PMID: 18184972
-
Li A, Walling J, Kotliarov Y, Center A, Steed ME, Ahn SJ, et al. (2008) Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas. Mol Cancer Res 6: 21-30. doi: 10.1158/1541-7786.MCR-07-0280 PMID: 18184972
-
(2008)
Mol Cancer Res
, vol.6
, pp. 21-30
-
-
Li, A.1
Walling, J.2
Kotliarov, Y.3
Center, A.4
Steed, M.E.5
Ahn, S.J.6
-
50
-
-
21044434153
-
Proteins and protein pattern differences between glioma cell lines and glioblastoma multiforme
-
PMID: 15897557
-
Vogel TW, Zhuang Z, Li J, Okamoto H, Furuta M, Lee YS, et al. (2005) Proteins and protein pattern differences between glioma cell lines and glioblastoma multiforme. Clin Cancer Res 11: 3624-3632 PMID: 15897557
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3624-3632
-
-
Vogel, T.W.1
Zhuang, Z.2
Li, J.3
Okamoto, H.4
Furuta, M.5
Lee, Y.S.6
-
51
-
-
37549063419
-
Is cell death a critical end point for anticancer therapies or is cytostasis sufficient?
-
PMID: 18094408
-
Rixe O, Fojo T (2007) Is cell death a critical end point for anticancer therapies or is cytostasis sufficient? Clin Cancer Res 13: 7280-7287. PMID: 18094408
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7280-7287
-
-
Rixe, O.1
Fojo, T.2
-
52
-
-
33748068792
-
Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma
-
PMID: 16912192
-
Chesler L, Schlieve C, Goldenberg DD, Kenney A, Kim G, McMillan A, et al. (2006) Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma. Cancer Res 66: 8139-8146. PMID: 16912192
-
(2006)
Cancer Res
, vol.66
, pp. 8139-8146
-
-
Chesler, L.1
Schlieve, C.2
Goldenberg, D.D.3
Kenney, A.4
Kim, G.5
McMillan, A.6
-
53
-
-
84901707531
-
Multiple lesions in receptor tyrosine kinase pathway determine glioblastoma response to pan-ERBB inhibitor PF-00299804 and PI3K/mTOR dual inhibitor PF-05212384
-
PMID: 24658109
-
Zhu Y, Shah K (2014) Multiple lesions in receptor tyrosine kinase pathway determine glioblastoma response to pan-ERBB inhibitor PF-00299804 and PI3K/mTOR dual inhibitor PF-05212384. Cancer Biol Ther 15: 815-822. doi: 10.4161/cbt.28585 PMID: 24658109
-
(2014)
Cancer Biol Ther
, vol.15
, pp. 815-822
-
-
Zhu, Y.1
Shah, K.2
-
54
-
-
0032977124
-
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines
-
PMID: 10416987
-
Ishii N, Maier D, Merlo A, Tada M, Sawamura Y, Diserens AC, et al. (1999) Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 9: 469-479. PMID: 10416987
-
(1999)
Brain Pathol
, vol.9
, pp. 469-479
-
-
Ishii, N.1
Maier, D.2
Merlo, A.3
Tada, M.4
Sawamura, Y.5
Diserens, A.C.6
-
55
-
-
0034816040
-
Differentiation therapy of human cancer: Basic science and clinical applications
-
PMID: 11578655
-
Leszczyniecka M, Roberts T, Dent P, Grant S, Fisher PB (2001) Differentiation therapy of human cancer: basic science and clinical applications. Pharmacol Ther 90: 105-156. PMID: 11578655
-
(2001)
Pharmacol Ther
, vol.90
, pp. 105-156
-
-
Leszczyniecka, M.1
Roberts, T.2
Dent, P.3
Grant, S.4
Fisher, P.B.5
-
56
-
-
84877305760
-
Role of PTEN in cholera toxin-induced SWO38 glioma cell differentiation
-
PMID: 23595342
-
Wang MH, Lin CL, Zhang JJ, Weng ZP, Hu T, Xie Q, et al. (2013) Role of PTEN in cholera toxin-induced SWO38 glioma cell differentiation. Mol Med Rep 7: 1912-1918. doi: 10.3892/mmr.2013.1434 PMID: 23595342
-
(2013)
Mol Med Rep
, vol.7
, pp. 1912-1918
-
-
Wang, M.H.1
Lin, C.L.2
Zhang, J.J.3
Weng, Z.P.4
Hu, T.5
Xie, Q.6
-
57
-
-
77749251930
-
Glycogen synthase kinase-3beta regulates astrocytic differentiation of U87-MG human glioblastoma cells
-
PMID: 20154711
-
Li Y, Lu HM, Li G, Yan GM (2010) Glycogen synthase kinase-3beta regulates astrocytic differentiation of U87-MG human glioblastoma cells. Acta Pharmacol Sin 31: 355-360. doi: 10.1038/aps.2010.10 PMID: 20154711
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 355-360
-
-
Li, Y.1
Lu, H.M.2
Li, G.3
Yan, G.M.4
-
58
-
-
78649880050
-
Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells
-
PMID: 20861085
-
Sunayama J, Sato A, Matsuda K, Tachibana K, Suzuki K, Narita Y, et al. (2010) Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells. Neuro Oncol 12: 1205-1219. doi: 10.1093/neuonc/noq103 PMID: 20861085
-
(2010)
Neuro Oncol
, vol.12
, pp. 1205-1219
-
-
Sunayama, J.1
Sato, A.2
Matsuda, K.3
Tachibana, K.4
Suzuki, K.5
Narita, Y.6
-
59
-
-
84920986600
-
A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy
-
PMID: 26056598
-
Westhoff M-A, Karpel-Massler G, Bruhl O, Enzenmuller S, La Ferla-Bruhl K, Siegelin M, et al. (2014) A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy. Molecular and Cellular Therapies 2: 32. doi: 10.1186/2052-8426-2-32 PMID: 26056598
-
(2014)
Molecular and Cellular Therapies
, vol.2
, pp. 32
-
-
Westhoff, M.-A.1
Karpel-Massler, G.2
Bruhl, O.3
Enzenmuller, S.4
La Ferla-Bruhl, K.5
Siegelin, M.6
-
60
-
-
84858442412
-
Post-radiation increase in VEGF enhances glioma cell motility in vitro
-
PMID: 22356893
-
Kil WJ, Tofilon PJ, Camphausen K (2012) Post-radiation increase in VEGF enhances glioma cell motility in vitro. Radiat Oncol 7: 25. doi: 10.1186/1748-717X-7-25 PMID: 22356893
-
(2012)
Radiat Oncol
, vol.7
, pp. 25
-
-
Kil, W.J.1
Tofilon, P.J.2
Camphausen, K.3
|