PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

Oncotarget

Volumn 4, Issue 8, 2013, Pages 1266-1279

  Gont, Alexander ^a,b   Hanson, Jennifer E L ^a   Lavictoire, Sylvie J ^a   Parolin, Doris A E ^a   Daneshmand, Manijeh ^a,b   Restall, Ian J ^a,b   Soucie, Mathieu ^a,b   Nicholas, Garth ^a,b   Woulfe, John ^a,b   Kassam, Amin ^b   Da Silva, Vasco F ^b   Lorimer, Ian A J ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Glioblastoma; Glioma; Lgl; PKC ; PTEN; Tumor initiating cell

Indexed keywords

LETHAL GIANT LARVAE PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE C; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CANCER CELL; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; GENE SILENCING; GLIOBLASTOMA; GLIOBLASTOMA TUMOR INITIATING CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INACTIVATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN NEOPLASMS; CELL DIFFERENTIATION; CYTOSKELETAL PROTEINS; GLIOBLASTOMA; HETEROGRAFTS; HUMANS; MICE; MICE, SCID; PHOSPHORYLATION; PROTEIN KINASE C; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84884346038     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1164     Document Type: Article

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