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Volumn 63, Issue 31, 2015, Pages 7024-7031

Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells

Author keywords

colitis; inflammation; majonoside R2; ocotillol; Th17 cell

Indexed keywords

CELLS; CYTOLOGY; DISEASES; MAMMALS; METABOLITES; NITRIC OXIDE;

EID: 84938709725     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b02183     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy, K. J.; Powrie, F. Intestinal homeostasis and its breakdown in inflammatory bowel disease Nature 2011, 474, 298-306 10.1038/nature10208
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 2
    • 2442712941 scopus 로고    scopus 로고
    • Epidemiology of IBD during the twentieth century: An integrated view
    • Binder, V. Epidemiology of IBD during the twentieth century: An integrated view Best Pract. Res. Clin. Gastroenterol. 2004, 18, 463-479 10.1016/j.bpg.2003.12.002
    • (2004) Best Pract. Res. Clin. Gastroenterol. , vol.18 , pp. 463-479
    • Binder, V.1
  • 3
    • 0038208014 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Dysfunction of GALT and gut bacterial flora (II)
    • Chandran, P.; Satthaporn, S.; Robins, A.; Eremin, O. Inflammatory bowel disease: Dysfunction of GALT and gut bacterial flora (II) Surgeon 2003, 1, 125-136 10.1016/S1479-666X(03)80091-4
    • (2003) Surgeon , vol.1 , pp. 125-136
    • Chandran, P.1    Satthaporn, S.2    Robins, A.3    Eremin, O.4
  • 4
    • 84920971304 scopus 로고    scopus 로고
    • Does the microbiota play a role in the pathogenesis of autoimmune diseases?
    • McLean, M. H.; Dieguez, D., Jr; Miller, L. M.; Young, H. A. Does the microbiota play a role in the pathogenesis of autoimmune diseases? Gut 2015, 64, 332-341 10.1136/gutjnl-2014-308514
    • (2015) Gut , vol.64 , pp. 332-341
    • McLean, M.H.1    Dieguez, D.2    Miller, L.M.3    Young, H.A.4
  • 5
    • 84883772859 scopus 로고    scopus 로고
    • Induced and natural regulatory T cells in the development of inflammatory bowel disease
    • Mayne, C. G.; Williams, C. B. Induced and natural regulatory T cells in the development of inflammatory bowel disease Inflammatory Bowel Dis. 2013, 19, 1772-1788 10.1097/MIB.0b013e318281f5a3
    • (2013) Inflammatory Bowel Dis. , vol.19 , pp. 1772-1788
    • Mayne, C.G.1    Williams, C.B.2
  • 6
    • 77249137663 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease
    • Eastaff-Leung, N.; Mabarrack, N.; Barbour, A.; Cummins, A.; Barry, S. Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease J. Clin. Immunol. 2010, 30, 80-89 10.1007/s10875-009-9345-1
    • (2010) J. Clin. Immunol. , vol.30 , pp. 80-89
    • Eastaff-Leung, N.1    Mabarrack, N.2    Barbour, A.3    Cummins, A.4    Barry, S.5
  • 8
    • 84859879397 scopus 로고    scopus 로고
    • RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation
    • Kanai, T.; Mikami, Y.; Sujino, T.; Hisamatsu, T.; Hibi, T. RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation Mucosal Immunol. 2012, 5, 240-224 10.1038/mi.2012.6
    • (2012) Mucosal Immunol. , vol.5 , pp. 240-224
    • Kanai, T.1    Mikami, Y.2    Sujino, T.3    Hisamatsu, T.4    Hibi, T.5
  • 11
    • 84860996207 scopus 로고    scopus 로고
    • Th17-related cytokines in inflammatory bowel diseases: Friends or foes?
    • Monteleone, I.; Sarra, M.; Pallone, F.; Monteleone, G. Th17-related cytokines in inflammatory bowel diseases: friends or foes? Curr. Mol. Med. 2012, 12, 592-597 10.2174/156652412800620066
    • (2012) Curr. Mol. Med. , vol.12 , pp. 592-597
    • Monteleone, I.1    Sarra, M.2    Pallone, F.3    Monteleone, G.4
  • 12
    • 2442621078 scopus 로고    scopus 로고
    • Combination of the pro-inflammatory cytokines IL-1, TNF-alpha and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-kappaB in osteoblast-like cells
    • Granet, C.; Miossec, P. Combination of the pro-inflammatory cytokines IL-1, TNF-alpha and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-kappaB in osteoblast-like cells Cytokine 2004, 26, 169-177 10.1016/j.cyto.2004.03.002
    • (2004) Cytokine , vol.26 , pp. 169-177
    • Granet, C.1    Miossec, P.2
  • 13
    • 77956136772 scopus 로고    scopus 로고
    • Pharmacotherapy: Concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets
    • Gizinski, A. M.; Fox, D. A.; Sarkar, S. Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets Best Pract. Res. Clin. Rheumatol. 2010, 24, 463-477 10.1016/j.berh.2009.12.015
    • (2010) Best Pract. Res. Clin. Rheumatol. , vol.24 , pp. 463-477
    • Gizinski, A.M.1    Fox, D.A.2    Sarkar, S.3
  • 14
    • 0037532532 scopus 로고    scopus 로고
    • Chemical constituents and biological activities of Vietnamese medicinal plants
    • Banskota, A. H.; Tezuka, Y.; Tran, Q. L.; Kadota, S. Chemical constituents and biological activities of Vietnamese medicinal plants Curr. Top. Med. Chem. 2003, 3, 227-248 10.2174/1568026033392516
    • (2003) Curr. Top. Med. Chem. , vol.3 , pp. 227-248
    • Banskota, A.H.1    Tezuka, Y.2    Tran, Q.L.3    Kadota, S.4
  • 15
    • 0030747737 scopus 로고    scopus 로고
    • Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: Possible involvement of neuroactive steroids
    • Huong, N. T. T.; Matsumoto, K.; Yamasaki, K.; Watanabe, H. Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: possible involvement of neuroactive steroids Life Sci. 1997, 61, 395-402 10.1016/S0024-3205(97)00396-2
    • (1997) Life Sci. , vol.61 , pp. 395-402
    • Huong, N.T.T.1    Matsumoto, K.2    Yamasaki, K.3    Watanabe, H.4
  • 16
    • 0029089937 scopus 로고
    • Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot-shock stress-induced antinociception in mice
    • Huong, N. T. T.; Matsumoto, K.; Yamasaki, K.; Duc, N. M.; Nham, N. T.; Watanabe, H. Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot-shock stress-induced antinociception in mice Pharmacol., Biochem. Behav. 1995, 52, 427-432 10.1016/0091-3057(95)00133-H
    • (1995) Pharmacol., Biochem. Behav. , vol.52 , pp. 427-432
    • Huong, N.T.T.1    Matsumoto, K.2    Yamasaki, K.3    Duc, N.M.4    Nham, N.T.5    Watanabe, H.6
  • 17
    • 0027763539 scopus 로고
    • Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. i
    • Minh Duc, N.; Thoi Nham, N.; Kasai, R.; Ito, A.; Yamasaki, K.; Tanaka, O. Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I Chem. Pharm. Bull. 1993, 41, 2010-2014 10.1248/cpb.41.2010
    • (1993) Chem. Pharm. Bull. , vol.41 , pp. 2010-2014
    • Minh Duc, N.1    Thoi Nham, N.2    Kasai, R.3    Ito, A.4    Yamasaki, K.5    Tanaka, O.6
  • 18
    • 84921928363 scopus 로고    scopus 로고
    • Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity
    • Le, T. H.; Lee, S. Y.; Kim, T. R.; Kim, J. Y.; Kwon, S. W.; Nguyen, N. K.; Park, J. H.; Nguyen, M. D. Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity J. Ginseng Res. 2014, 38, 154-9 10.1016/j.jgr.2013.11.015
    • (2014) J. Ginseng Res. , vol.38 , pp. 154-159
    • Le, T.H.1    Lee, S.Y.2    Kim, T.R.3    Kim, J.Y.4    Kwon, S.W.5    Nguyen, N.K.6    Park, J.H.7    Nguyen, M.D.8
  • 19
    • 84866252422 scopus 로고    scopus 로고
    • Brazilian propolis inhibits the differentiation of Th17 cells by inhibition of interleukin-6-induced phosphorylation of signal transducer and activator of transcription 3
    • Okamoto, Y.; Tanaka, M.; Fukui, T.; Masuzawa, T. Brazilian propolis inhibits the differentiation of Th17 cells by inhibition of interleukin-6-induced phosphorylation of signal transducer and activator of transcription 3 Immunopharmacol. Immunotoxicol. 2012, 34, 803-809 10.3109/08923973.2012.657304
    • (2012) Immunopharmacol. Immunotoxicol. , vol.34 , pp. 803-809
    • Okamoto, Y.1    Tanaka, M.2    Fukui, T.3    Masuzawa, T.4
  • 20
    • 84885658793 scopus 로고    scopus 로고
    • Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways
    • Jang, S. E.; Hyam, S. R.; Jeong, J. J.; Han, M. J.; Kim, D. H. Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways Br. J. Pharmacol. 2013, 170, 1078-1091 10.1111/bph.12333
    • (2013) Br. J. Pharmacol. , vol.170 , pp. 1078-1091
    • Jang, S.E.1    Hyam, S.R.2    Jeong, J.J.3    Han, M.J.4    Kim, D.H.5
  • 21
    • 84907942460 scopus 로고    scopus 로고
    • Ursolic acid isolated from the seed of Cornus officinalis ameliorates colitis in mice by inhibiting the binding of lipopolysaccharide to Toll-like receptor 4 on macrophages
    • Jang, S. E.; Jeong, J. J.; Hyam, S. R.; Han, M. J.; Kim, D. H. Ursolic acid isolated from the seed of Cornus officinalis ameliorates colitis in mice by inhibiting the binding of lipopolysaccharide to Toll-like receptor 4 on macrophages J. Agric. Food Chem. 2014, 62, 9711-9721 10.1021/jf501487v
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 9711-9721
    • Jang, S.E.1    Jeong, J.J.2    Hyam, S.R.3    Han, M.J.4    Kim, D.H.5
  • 22
    • 84872743018 scopus 로고    scopus 로고
    • Ginsenoside Rh1 ameliorates high fat diet-induced obesity in mice by inhibiting adipocyte differentiation
    • Gu, W.; Kim, K. A.; Kim, D. H. Ginsenoside Rh1 ameliorates high fat diet-induced obesity in mice by inhibiting adipocyte differentiation Biol. Pharm. Bull. 2013, 36, 102-107 10.1248/bpb.b12-00558
    • (2013) Biol. Pharm. Bull. , vol.36 , pp. 102-107
    • Gu, W.1    Kim, K.A.2    Kim, D.H.3
  • 23
    • 77249137663 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease
    • Eastaff-Leung, N.; Mabarrack, N.; Barbour, A.; Cummins, A.; Barry, S. Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease J. Clin. Immunol. 2010, 30, 80-89 10.1007/s10875-009-9345-1
    • (2010) J. Clin. Immunol. , vol.30 , pp. 80-89
    • Eastaff-Leung, N.1    Mabarrack, N.2    Barbour, A.3    Cummins, A.4    Barry, S.5
  • 24
    • 79959563146 scopus 로고    scopus 로고
    • Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation - The key step of inflammation
    • Joh, E. H.; Lee, I. A.; Jung, I. H.; Kim, D. H. Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation - the key step of inflammation Biochem. Pharmacol. 2011, 82, 278-286 10.1016/j.bcp.2011.05.003
    • (2011) Biochem. Pharmacol. , vol.82 , pp. 278-286
    • Joh, E.H.1    Lee, I.A.2    Jung, I.H.3    Kim, D.H.4
  • 25
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu, J.; Paul, W. E. CD4 T cells: fates, functions, and faults Blood 2008, 112, 1557-1569 10.1182/blood-2008-05-078154
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 26
    • 80051935235 scopus 로고    scopus 로고
    • Antigen-specific TGF-β-induced regulatory T cells secrete chemokines, regulate T cell trafficking, and suppress ongoing autoimmunity
    • Nguyen, T. L.; Sullivan, N. L.; Ebel, M.; Teague, R. M.; DiPaolo, R. J. Antigen-specific TGF-β-induced regulatory T cells secrete chemokines, regulate T cell trafficking, and suppress ongoing autoimmunity J. Immunol. 2011, 187, 1745-1753 10.4049/jimmunol.1004112
    • (2011) J. Immunol. , vol.187 , pp. 1745-1753
    • Nguyen, T.L.1    Sullivan, N.L.2    Ebel, M.3    Teague, R.M.4    DiPaolo, R.J.5
  • 28
    • 84861694481 scopus 로고    scopus 로고
    • A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells
    • Rauen, T.; Juang, Y. T.; Hedrich, C. M.; Kis-Toth, K.; Tsokos, G. C. A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells Genes Immun. 2012, 13, 346-350 10.1038/gene.2011.85
    • (2012) Genes Immun. , vol.13 , pp. 346-350
    • Rauen, T.1    Juang, Y.T.2    Hedrich, C.M.3    Kis-Toth, K.4    Tsokos, G.C.5
  • 29
    • 84874112880 scopus 로고    scopus 로고
    • Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin
    • Tao, F.; Qian, C.; Guo, W.; Luo, Q.; Xu, Q.; Sun, Y. Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin Biochem. Pharmacol. 2013, 85, 798-807 10.1016/j.bcp.2012.12.002
    • (2013) Biochem. Pharmacol. , vol.85 , pp. 798-807
    • Tao, F.1    Qian, C.2    Guo, W.3    Luo, Q.4    Xu, Q.5    Sun, Y.6
  • 30
    • 65849187567 scopus 로고    scopus 로고
    • Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells
    • Kang, H. K.; Ecklund, D.; Liu, M.; Datta, S. K. Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells Arthritis Res. Ther. 2009, 11, R59 10.1186/ar2682
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 59
    • Kang, H.K.1    Ecklund, D.2    Liu, M.3    Datta, S.K.4
  • 31
    • 79951921353 scopus 로고    scopus 로고
    • Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation
    • Yang, J.; Yang, X.; Chu, Y.; Li, M. Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation PLoS One 2011, 6, e17164 10.1371/journal.pone.0017164
    • (2011) PLoS One , vol.6 , pp. 17164
    • Yang, J.1    Yang, X.2    Chu, Y.3    Li, M.4
  • 32
    • 79952101240 scopus 로고    scopus 로고
    • Regulatory role of resveratrol on Th17 in autoimmune disease
    • Petro, T. M. Regulatory role of resveratrol on Th17 in autoimmune disease Int. Immunopharmacol. 2011, 11, 310-318 10.1016/j.intimp.2010.07.011
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 310-318
    • Petro, T.M.1
  • 33
    • 84862925405 scopus 로고    scopus 로고
    • Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng
    • Kim, D. H. Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng J. Ginseng Res. 2012, 36, 1-15 10.5142/jgr.2012.36.1.1
    • (2012) J. Ginseng Res. , vol.36 , pp. 1-15
    • Kim, D.H.1
  • 34
    • 84919708991 scopus 로고    scopus 로고
    • Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation
    • Zhang, J.; Ding, L.; Wang, B.; Ren, G.; Sun, A.; Deng, C.; Wei, X.; Mani, S.; Wang, Z.; Dou, W. Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation J. Pharmacol. Exp. Ther. 2015, 352, 315-324 10.1124/jpet.114.218750
    • (2015) J. Pharmacol. Exp. Ther. , vol.352 , pp. 315-324
    • Zhang, J.1    Ding, L.2    Wang, B.3    Ren, G.4    Sun, A.5    Deng, C.6    Wei, X.7    Mani, S.8    Wang, Z.9    Dou, W.10
  • 36
    • 84862823665 scopus 로고    scopus 로고
    • Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
    • Yang, X. L.; Guo, T. K.; Wang, Y. H.; Huang, Y. H.; Liu, X.; Wang, X. X.; Li, W.; Zhao, X.; Wang, L. P.; Yan, S.; Wu, D.; Wu, Y. J. Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis Int. Immunopharmacol. 2012, 12, 408-414 10.1016/j.intimp.2011.12.014
    • (2012) Int. Immunopharmacol. , vol.12 , pp. 408-414
    • Yang, X.L.1    Guo, T.K.2    Wang, Y.H.3    Huang, Y.H.4    Liu, X.5    Wang, X.X.6    Li, W.7    Zhao, X.8    Wang, L.P.9    Yan, S.10    Wu, D.11    Wu, Y.J.12
  • 37
    • 84895195545 scopus 로고    scopus 로고
    • Ginsenoside metabolite compound K promotes recovery of dextran sulfate sodium-induced colitis and inhibits inflammatory responses by suppressing NF-κB activation
    • Li, J.; Zhong, W.; Wang, W.; Hu, S.; Yuan, J.; Zhang, B.; Hu, T.; Song, G. Ginsenoside metabolite compound K promotes recovery of dextran sulfate sodium-induced colitis and inhibits inflammatory responses by suppressing NF-κB activation PLoS One 2014, 9, e87810 10.1371/journal.pone.0087810
    • (2014) PLoS One , vol.9 , pp. 87810
    • Li, J.1    Zhong, W.2    Wang, W.3    Hu, S.4    Yuan, J.5    Zhang, B.6    Hu, T.7    Song, G.8
  • 38
    • 84905114410 scopus 로고    scopus 로고
    • Ginsenoside Rh2 alleviates dextran sulfate sodium-induced colitis via augmenting TGFβ signaling
    • Ye, H.; Wu, Q.; Zhu, Y.; Guo, C.; Zheng, X. Ginsenoside Rh2 alleviates dextran sulfate sodium-induced colitis via augmenting TGFβ signaling Mol. Biol. Rep. 2014, 41, 5485-5490 10.1007/s11033-014-3422-0
    • (2014) Mol. Biol. Rep. , vol.41 , pp. 5485-5490
    • Ye, H.1    Wu, Q.2    Zhu, Y.3    Guo, C.4    Zheng, X.5
  • 39
    • 84866639068 scopus 로고    scopus 로고
    • Ginsenoside Re ameliorates inflammation by inhibiting the binding of lipopolysaccharide to TLR4 on macrophages
    • Lee, I. A.; Hyam, S. R.; Jang, S. E.; Han, M. J.; Kim, D. H. Ginsenoside Re ameliorates inflammation by inhibiting the binding of lipopolysaccharide to TLR4 on macrophages J. Agric. Food Chem. 2012, 60, 9595-9602 10.1021/jf301372g
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 9595-9602
    • Lee, I.A.1    Hyam, S.R.2    Jang, S.E.3    Han, M.J.4    Kim, D.H.5


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