Ursolic acid isolated from the seed of cornus officinalis ameliorates colitis in mice by inhibiting the binding of lipopolysaccharide to toll-like receptor 4 on macrophages

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 40, 2014, Pages 9711-9721

  Jang, Se Eun ^a   Jeong, Jin Ju ^a   Hyam, Supriya R ^a   Han, Myung Joo ^a   Kim, Dong Hyun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

colitis; Cornus officinalis; macrophage; toll like receptor 4; ursolic acid

Indexed keywords

COLITIS; CORNUS OFFICINALIS; LIPOPOLYSACCHARIDES; TOLL-LIKE RECEPTOR 4; URSOLIC ACID;

MACROPHAGES;

AUTACOID; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PEPTIDOGLYCAN; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4; TRINITROBENZENESULFONIC ACID; TRITERPENE; URSOLIC ACID;

ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; CHEMISTRY; COLITIS; CORNUS; DRUG EFFECTS; GENETICS; MALE; METABOLISM; PERITONEUM MACROPHAGE; PLANT SEED;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COLITIS; CORNUS; CYTOKINES; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE, INBRED C57BL; NF-KAPPA B; PEPTIDOGLYCAN; SEEDS; TOLL-LIKE RECEPTOR 4; TRINITROBENZENESULFONIC ACID; TRITERPENES;

EID: 84907942460     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf501487v     Document Type: Article

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