Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells

Arthritis Research and Therapy

Volumn 11, Issue 2, 2009, Pages

  Kang, Hee Kap ^a   Ecklund, Diane ^a   Liu, Michael ^a   Datta, Syamal K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; CYCLOOXYGENASE 2; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G ANTIBODY; PROTEIN BCL XL; AUTOANTIBODY; AUTOANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 17;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DIETARY INTAKE; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; GLOMERULONEPHRITIS; HISTOPATHOLOGY; IMMUNE SYSTEM; LUPUS LIKE SYNDROME; MOUSE; NEPHRITIS; NONHUMAN; NUCLEOSOME; OPTIMAL DRUG DOSE; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL; TH17 CELL; TISSUE CULTURE; ANIMAL; ANTIGEN PRESENTATION; B LYMPHOCYTE; BIOSYNTHESIS; BLOOD; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGY; LUPUS ERYTHEMATOSUS NEPHRITIS; LYMPHOCYTE ACTIVATION; NEW ZEALAND BLACK MOUSE; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; APIGENIN; APOPTOSIS; AUTOANTIBODIES; AUTOANTIGENS; B-LYMPHOCYTES; CYCLOOXYGENASE 2; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-17; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NZB; NUCLEOSOMES; T-LYMPHOCYTE SUBSETS; TH1 CELLS;

EID: 65849187567     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2682     Document Type: Article

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