IL-1α gene deletion protects oligodendrocytes after spinal cord injury through upregulation of the survival factor Tox3

Journal of Neuroscience

Volumn 35, Issue 30, 2015, Pages 10715-10730

  Bastien, Dominic ^a   Landete, Victor Bellver ^a   Lessard, Martine ^a   Vallières, Nicolas ^a   Champagne, Mathieu ^a   Takashima, Akira ^b   Tremblay, Marie Ève ^a   Doyon, Yannick ^a   Lacroix, Steve ^a  

^a Université Laval   (Canada)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Cytokine; Microglia; Neurodegeneration; Neuroimmunology; Neuroinflammation; Neutrophil

Indexed keywords

HIGH MOBILITY GROUP B PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TRANSCRIPTOME; PROGESTERONE RECEPTOR; TNRC9 PROTEIN, HUMAN;

ADULT; ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CELL INFILTRATION; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; FLOW CYTOMETRY; GENE DELETION; GENE OVEREXPRESSION; HISTOLOGY; HYPOXIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MACROPHAGE; MICROARRAY ANALYSIS; MICROGLIA; MOUSE; NEUTROPHIL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; TISSUE INJURY; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CONFOCAL MICROSCOPY; CONVALESCENCE; DISEASE MODEL; DNA MICROARRAY; FEMALE; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM; NERVE DEGENERATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; GENE DELETION; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1ALPHA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NERVE DEGENERATION; OLIGODENDROGLIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROGESTERONE; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; UP-REGULATION;

EID: 84938498544     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0498-15.2015     Document Type: Article

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