SCOPUS 정보 검색 플랫폼

Volumn 348, Issue 8, 2015, Pages 556-563

Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore

(6) Szałaj, Natalia a Bajda, Marek a Dudek, Katarzyna a Brus, Boris b Gobec, Stanislav b Malawska, Barbara a

a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE (Poland)

b UNIVERSITY OF LJUBLJANA (Slovenia)

Author keywords

Alzheimer's disease; Beta amyloid aggregation inhibitors; Cholinesterase inhibitors; Multitarget directed ligand

Indexed keywords

AMYLOID BETA PROTEIN; BENZYLAMINE DERIVATIVE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DONEPEZIL; HETERODIMER; SACCHARIN; ACETYLCHOLINESTERASE; ACHE PROTEIN, HUMAN; AMYLOID BETA-PROTEIN (1-42); GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HETEROCYCLIC COMPOUND; LIGAND; PEPTIDE FRAGMENT; PROTEIN BINDING;

ALZHEIMER DISEASE; ARTICLE; BLOOD BRAIN BARRIER; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; HUMAN; IC50; IN VITRO STUDY; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN TARGETING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; BINDING SITE; CAPILLARY PERMEABILITY; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVE SITE; ENZYMOLOGY; KINETICS; METABOLISM; MOLECULAR DOCKING; MOLECULARLY TARGETED THERAPY; PROTEIN CONFORMATION; PROTEINOSIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BENZYLAMINES; BINDING SITES; BINDING, COMPETITIVE; BLOOD-BRAIN BARRIER; BUTYRYLCHOLINESTERASE; CAPILLARY PERMEABILITY; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; DRUG DESIGN; GPI-LINKED PROTEINS; HETEROCYCLIC COMPOUNDS; KINETICS; LIGANDS; MOLECULAR DOCKING SIMULATION; MOLECULAR TARGETED THERAPY; PEPTIDE FRAGMENTS; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN BINDING; PROTEIN CONFORMATION; SACCHARIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84938421040 PISSN: 03656233 EISSN: 15214184 Source Type: Journal
DOI: 10.1002/ardp.201500117 Document Type: Article

Times cited : (10)

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