SCOPUS 정보 검색 플랫폼

Volumn 345, Issue 7, 2012, Pages 509-516

Design, synthesis and evaluation of novel 2-(Aminoalkyl)-isoindoline-1,3- dione derivatives as dual-binding site acetylcholinesterase inhibitors

(6) Ignasik, Michalina a Bajda, Marek a Guzior, Natalia a Prinz, Michaela b Holzgrabe, Ulrike b Malawska, Barbara a

a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE (Poland)

b UNIVERSITY OF WÜRZBURG (Germany)

Author keywords

2 (Aminoalkyl) isoindoline 1,3 dione derivatives; A aggregation; Acetylcholinesterase inhibitors; Electrophoretically mediated microanalysis (EMMA); Molecular modeling

Indexed keywords

2 (3 DIETHYLAMINOHEPTYL)ISOINDOLINE 1,3 DIONE; 2 (3 DIETHYLAMINOHEXYL)ISOINDOLINE 1,3 DIONE; 2 (3 DIETHYLAMINOOCTYL)ISOINDOLINE 1,3 DIONE; 2 (3 DIETHYLAMINOPROPYL)ISOINDOLINE 1,3 DIONE; 2 (4 DIETHYLAMINOBUTYL)ISOINDOLINE 1,3 DIONE; 2 (5 DIETHYLAMIOPENTYL)ISOINDOLINE 1,3 DIONE; ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN; CARBENE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; ISOINDOLINE 1,3 DIONE DERIVATIVE; UNCLASSIFIED DRUG;

AMYLOID PLAQUE; ARTICLE; BINDING SITE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; IC 50; MICROANALYSIS; MOLECULAR MODEL; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ACETYLCHOLINESTERASE; ANIMALS; BINDING SITES; BUTYRYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ELECTROPHORUS; HORSES; ISOINDOLES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; REGRESSION ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84863660604 PISSN: 03656233 EISSN: 15214184 Source Type: Journal
DOI: 10.1002/ardp.201100423 Document Type: Article

Times cited : (55)

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