Structure-based search for new inhibitors of cholinesterases

International Journal of Molecular Sciences

Volumn 14, Issue 3, 2013, Pages 5608-5632

  Bajda, Marek ^a   Wiȩckowska, Anna ^a   Hebda, Michalina ^a   Guzior, Natalia ^a   Sotriffer, Christoph A ^b   Malawska, Barbara ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Cholinesterases inhibitors; Drug design; Fragment based design

Indexed keywords

2 (6 DIETHYLAMINOHEXYL)ISOINDOLINE 1,3 DIONE; 2 (7 DIETHYLAMINOHEPTYL)ISOINDOLINE 1,3 DIONE; 2 (8 DIETHYLAMINOOCTYL)ISOINDOLINE 1,3 DIONE; 2 [3 (1 BENZYLPIPERIDIN 4 YLAMINO)PROPYL]ISOINDOLINE 1,3 DIONE; 2 [5 (2 FLOUROBENZYLAMINO)PENTYL]ISOINDOLINE 1,3 DIONE; 2 [6 (1 BENZYLPIPERIDIN 4 YLAMINO)HEXYL]ISOINDOLINE 1,3 DIONE; 2 [6 (BENZYLAMINO)HEXYL]ISOINDOLINE 1,3 DIONE; 2 [6 (BENZYLAMINO)PENTYL]ISOINDOLINE 1,3 DIONE; 2 [6 [1 (3 CHLOROBENZYL)PIPERIDIN 4 YLAMINO]HEXYL]ISOINDOLINE 1,3 DIONE; ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DECAMETHONIUM; DONEPEZIL; EDROPHONIUM; ESTERASE INHIBITOR; GALANTAMINE; GANSTIGMINE; HETERODIMER; PRALIDOXIME; RIVASTIGMINE; TACRINE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME STRUCTURE; IC 50; MOLECULAR DOCKING; STRUCTURE ANALYSIS;

EID: 84875061394     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14035608     Document Type: Article

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