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Volumn 18, Issue 8, 2015, Pages 1094-1100

The role of ventral striatal cAMP signaling in stress-induced behaviors

(18)  Plattner, Florian a   Hayashi, Kanehiro a,k,l   Hernández, Adan a   Benavides, David R a,k   Tassin, Tara C a   Tan, Chunfeng a   Day, Jonathan b   Fina, Maggy W c   Yuen, Eunice Y d   Yan, Zhen d   Goldberg, Matthew S a,c   Nairn, Angus C e,f   Greengard, Paul f   Nestler, Eric J g   Taussig, Ronald c   Nishi, Akinori h   Houslay, Miles D i   Bibb, James A a,c,j  


Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIN DEPENDENT KINASE 5; DOPAMINE 1 RECEPTOR; PHOSPHODIESTERASE IV; CDK5 PROTEIN, MOUSE; CYCLIC AMP DEPENDENT PROTEIN KINASE;

EID: 84938417105     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4066     Document Type: Article
Times cited : (67)

References (62)
  • 1
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling
    • Conti, M. & Beavo, J. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu. Rev. Biochem. 76, 481-511 (2007).
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 481-511
    • Conti, M.1    Beavo, J.2
  • 2
    • 75749117558 scopus 로고    scopus 로고
    • Underpinning compartmentalized cAMP signaling through targeted cAMP breakdown
    • Houslay, M.D. Underpinning compartmentalized cAMP signaling through targeted cAMP breakdown. Trends Biochem. Sci. 35, 91-100 (2010).
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 91-100
    • Houslay, M.D.1
  • 3
    • 0030006920 scopus 로고    scopus 로고
    • Phosphorylation and activation of a cAMP-specifc phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation
    • Sette, C. & Conti, M. Phosphorylation and activation of a cAMP-specifc phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation. J. Biol. Chem. 271, 16526-16534 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 16526-16534
    • Sette, C.1    Conti, M.2
  • 4
    • 0036016114 scopus 로고    scopus 로고
    • Long PDE4 cAMP-specifc phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in upstream conserved region 1 (UCR1)
    • MacKenzie, S.J. et al. Long PDE4 cAMP-specifc phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in upstream conserved region 1 (UCR1). Br. J. Pharmacol. 136, 421-433 (2002).
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 421-433
    • MacKenzie, S.J.1
  • 5
    • 0033540078 scopus 로고    scopus 로고
    • Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    • Bibb, J.A. et al. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature 402, 669-671 (1999).
    • (1999) Nature , vol.402 , pp. 669-671
    • Bibb, J.A.1
  • 7
    • 33749164973 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 in synaptic plasticity, learning and memory
    • Angelo, M., Plattner, F. & Giese, K.P. Cyclin-dependent kinase 5 in synaptic plasticity, learning and memory. J. Neurochem. 99, 353-370 (2006).
    • (2006) J. Neurochem. , vol.99 , pp. 353-370
    • Angelo, M.1    Plattner, F.2    Giese, K.P.3
  • 8
    • 84895438578 scopus 로고    scopus 로고
    • Memory enhancement by targeting Cdk5 regulation of NR2B
    • Plattner, F. et al. Memory enhancement by targeting Cdk5 regulation of NR2B. Neuron 81, 1070-1083 (2014).
    • (2014) Neuron , vol.81 , pp. 1070-1083
    • Plattner, F.1
  • 9
    • 84902152605 scopus 로고    scopus 로고
    • Ischemic stroke injury is mediated by aberrant Cdk5
    • Meyer, D.A. et al. Ischemic stroke injury is mediated by aberrant Cdk5. J. Neurosci. 34, 8259-8267 (2014).
    • (2014) J. Neurosci. , vol.34 , pp. 8259-8267
    • Meyer, D.A.1
  • 10
    • 79954633210 scopus 로고    scopus 로고
    • The role of Cdk5 in cognition and neuropsychiatric and neurological pathology
    • Barnett, D.G. & Bibb, J.A. The role of Cdk5 in cognition and neuropsychiatric and neurological pathology. Brain Res. Bull. 85, 9-13 (2011).
    • (2011) Brain Res. Bull. , vol.85 , pp. 9-13
    • Barnett, D.G.1    Bibb, J.A.2
  • 11
    • 80054045373 scopus 로고    scopus 로고
    • Cyclin-dependent kinases in brain development and disease
    • Su, S.C. & Tsai, L.H. Cyclin-dependent kinases in brain development and disease. Annu. Rev. Cell Dev. Biol. 27, 465-491 (2011).
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27 , pp. 465-491
    • Su, S.C.1    Tsai, L.H.2
  • 13
    • 45849142126 scopus 로고    scopus 로고
    • Involvement of septal Cdk5 in the emergence of excessive anxiety induced by stress
    • Bignante, E.A. et al. Involvement of septal Cdk5 in the emergence of excessive anxiety induced by stress. Eur. Neuropsychopharmacol. 18, 578-588 (2008).
    • (2008) Eur. Neuropsychopharmacol. , vol.18 , pp. 578-588
    • Bignante, E.A.1
  • 14
    • 77952542972 scopus 로고    scopus 로고
    • Previous stress exposure enhances both anxiety-like behavior and p35 levels in the basolateral amygdala complex: Modulation by midazolam
    • Bignante, E.A., Paglini, G. & Molina, V.A. Previous stress exposure enhances both anxiety-like behavior and p35 levels in the basolateral amygdala complex: modulation by midazolam. Eur. Neuropsychopharmacol. 20, 388-397 (2010).
    • (2010) Eur. Neuropsychopharmacol. , vol.20 , pp. 388-397
    • Bignante, E.A.1    Paglini, G.2    Molina, V.A.3
  • 15
    • 84862125015 scopus 로고    scopus 로고
    • Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behavior in rats
    • Zhu, W.L. et al. Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behavior in rats. Int. J. Neuropsychopharmacol. 15, 795-809 (2012).
    • (2012) Int. J. Neuropsychopharmacol. , vol.15 , pp. 795-809
    • Zhu, W.L.1
  • 16
    • 84899637787 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors
    • Zhong, P. et al. Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors. J. Neurosci. 34, 6352-6366 (2014).
    • (2014) J. Neurosci. , vol.34 , pp. 6352-6366
    • Zhong, P.1
  • 17
    • 0025872286 scopus 로고
    • Side and region dependent changes in dopamine activation with various durations of restraint stress
    • Carlson, J.N., Fitzgerald, L.W., Keller, R.W. Jr. & Glick, S.D. Side and region dependent changes in dopamine activation with various durations of restraint stress. Brain Res. 550, 313-318 (1991).
    • (1991) Brain Res. , vol.550 , pp. 313-318
    • Carlson, J.N.1    FitzGerald, L.W.2    Keller, R.W.3    Glick, S.D.4
  • 18
    • 0030946556 scopus 로고    scopus 로고
    • Effects of single and repeated footshock on dopamine release and metabolism in the brains of Fischer rats
    • Chrapusta, S.J., Wyatt, R.J. & Masserano, J.M. Effects of single and repeated footshock on dopamine release and metabolism in the brains of Fischer rats. J. Neurochem. 68, 2024-2031 (1997).
    • (1997) J. Neurochem. , vol.68 , pp. 2024-2031
    • Chrapusta, S.J.1    Wyatt, R.J.2    Masserano, J.M.3
  • 19
    • 84872937372 scopus 로고    scopus 로고
    • Dopamine neurons modulate neural encoding and expression of depression-related behavior
    • Tye, K.M. et al. Dopamine neurons modulate neural encoding and expression of depression-related behavior. Nature 493, 537-541 (2013).
    • (2013) Nature , vol.493 , pp. 537-541
    • Tye, K.M.1
  • 20
    • 84872925363 scopus 로고    scopus 로고
    • Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons
    • Chaudhury, D. et al. Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons. Nature 493, 532-536 (2013).
    • (2013) Nature , vol.493 , pp. 532-536
    • Chaudhury, D.1
  • 21
    • 34347407040 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation
    • Hawasli, A.H. et al. Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat. Neurosci. 10, 880-886 (2007).
    • (2007) Nat. Neurosci. , vol.10 , pp. 880-886
    • Hawasli, A.H.1
  • 22
    • 0035783417 scopus 로고    scopus 로고
    • Temporally controlled targeted somatic mutagenesis in the mouse brain
    • Weber, P., Metzger, D. & Chambon, P. Temporally controlled targeted somatic mutagenesis in the mouse brain. Eur. J. Neurosci. 14, 1777-1783 (2001).
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 1777-1783
    • Weber, P.1    Metzger, D.2    Chambon, P.3
  • 23
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler, E.J. & Hyman, S.E. Animal models of neuropsychiatric disorders. Nat. Neurosci. 13, 1161-1169 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 24
    • 36949041038 scopus 로고    scopus 로고
    • Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression
    • Schlaepfer, T.E. et al. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology 33, 368-377 (2008).
    • (2008) Neuropsychopharmacology , vol.33 , pp. 368-377
    • Schlaepfer, T.E.1
  • 25
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler, E.J. & Carlezon, W.A. Jr. The mesolimbic dopamine reward circuit in depression. Biol. Psychiatry 59, 1151-1159 (2006).
    • (2006) Biol. Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 26
    • 84860217457 scopus 로고    scopus 로고
    • Cognitive function in health and disease: The role of epigenetic mechanisms
    • Mungenast, A.E. & Tsai, L.H. Cognitive function in health and disease: the role of epigenetic mechanisms. Neurodegener. Dis. 10, 191-194 (2012).
    • (2012) Neurodegener. Dis. , vol.10 , pp. 191-194
    • Mungenast, A.E.1    Tsai, L.H.2
  • 27
    • 84885191156 scopus 로고    scopus 로고
    • Genome-wide pathway analysis in major depressive disorder
    • Song, G.G., Kim, J.H. & Lee, Y.H. Genome-wide pathway analysis in major depressive disorder. J. Mol. Neurosci. 51, 428-436 (2013).
    • (2013) J. Mol. Neurosci. , vol.51 , pp. 428-436
    • Song, G.G.1    Kim, J.H.2    Lee, Y.H.3
  • 28
    • 84875211424 scopus 로고    scopus 로고
    • A genome-wide association study of depressive symptoms
    • Hek, K. et al. A genome-wide association study of depressive symptoms. Biol. Psychiatry 73, 667-678 (2013).
    • (2013) Biol. Psychiatry , vol.73 , pp. 667-678
    • Hek, K.1
  • 29
    • 41549090857 scopus 로고    scopus 로고
    • Adenylyl cyclase-cyclicAMP signaling in mood disorders: Role of the crucial phosphorylating enzyme protein kinase A
    • Dwivedi, Y. & Pandey, G.N. Adenylyl cyclase-cyclicAMP signaling in mood disorders: role of the crucial phosphorylating enzyme protein kinase A. Neuropsychiatr. Dis. Treat. 4, 161-176 (2008).
    • (2008) Neuropsychiatr. Dis. Treat. , vol.4 , pp. 161-176
    • Dwivedi, Y.1    Pandey, G.N.2
  • 30
    • 84855297758 scopus 로고    scopus 로고
    • Signaling pathways underlying the pathophysiology and treatment of depression: Novel mechanisms for rapid-acting agents
    • Duman, R.S. & Voleti, B. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends Neurosci. 35, 47-56 (2012).
    • (2012) Trends Neurosci. , vol.35 , pp. 47-56
    • Duman, R.S.1    Voleti, B.2
  • 31
    • 84866038675 scopus 로고    scopus 로고
    • Downregulation of brain phosphodiesterase type IV measured with (11)C-(R)-rolipram positron emission tomography in major depressive disorder
    • Fujita, M. et al. Downregulation of brain phosphodiesterase type IV measured with (11)C-(R)-rolipram positron emission tomography in major depressive disorder. Biol. Psychiatry 72, 548-554 (2012).
    • (2012) Biol. Psychiatry , vol.72 , pp. 548-554
    • Fujita, M.1
  • 32
    • 84866045457 scopus 로고    scopus 로고
    • Evidence for global reduction in brain cyclic adenosine monophosphate signaling in depression
    • O'Donnell, J.M. & Xu, Y. Evidence for global reduction in brain cyclic adenosine monophosphate signaling in depression. Biol. Psychiatry 72, 524-525 (2012).
    • (2012) Biol. Psychiatry , vol.72 , pp. 524-525
    • O'Donnell, J.M.1    Xu, Y.2
  • 33
    • 35148895860 scopus 로고    scopus 로고
    • PDE inhibitors in psychiatry-future options for dementia, depression and schizophrenia? Drug Discov
    • Halene, T.B. & Siegel, S.J. PDE inhibitors in psychiatry-future options for dementia, depression and schizophrenia? Drug Discov. Today 12, 870-878 (2007).
    • (2007) Today , vol.12 , pp. 870-878
    • Halene, T.B.1    Siegel, S.J.2
  • 34
    • 61749093429 scopus 로고    scopus 로고
    • Phosphodiesterases in the central nervous system
    • Kleppisch, T. Phosphodiesterases in the central nervous system. Handb. Exp. Pharmacol. 191, 71-92 (2009).
    • (2009) Handb. Exp. Pharmacol. , vol.191 , pp. 71-92
    • Kleppisch, T.1
  • 35
    • 0021720605 scopus 로고
    • Results of a phase II study of the antidepressant effect of rolipram
    • Zeller, E., Stief, H.J. & Pfug, B. Sastre-y-Hernandez, M. Results of a phase II study of the antidepressant effect of rolipram. Pharmacopsychiatry 17, 188-190 (1984).
    • (1984) Pharmacopsychiatry , vol.17 , pp. 188-190
    • Zeller, E.1    Stief, H.J.2    Pfug, B.3    Sastre-y-Hernandez, M.4
  • 36
    • 0036790883 scopus 로고    scopus 로고
    • Antidepressant-like profle and reduced sensitivity to rolipram in mice defcient in the PDE4D phosphodiesterase enzyme
    • Zhang, H.T. et al. Antidepressant-like profle and reduced sensitivity to rolipram in mice defcient in the PDE4D phosphodiesterase enzyme. Neuropsychopharmacology 27, 587-595 (2002).
    • (2002) Neuropsychopharmacology , vol.27 , pp. 587-595
    • Zhang, H.T.1
  • 37
    • 1342264246 scopus 로고    scopus 로고
    • Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)
    • O'Donnell, J.M. & Zhang, H.T. Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends Pharmacol. Sci. 25, 158-163 (2004).
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 158-163
    • O'Donnell, J.M.1    Zhang, H.T.2
  • 38
    • 27344449614 scopus 로고    scopus 로고
    • Keynote review: Phosphodiesterase-4 as a therapeutic target
    • Houslay, M.D., Schafer, P. & Zhang, K.Y. Keynote review: phosphodiesterase-4 as a therapeutic target. Drug Discov. Today 10, 1503-1519 (2005).
    • (2005) Drug Discov. Today , vol.10 , pp. 1503-1519
    • Houslay, M.D.1    Schafer, P.2    Zhang, K.Y.3
  • 39
    • 74049158987 scopus 로고    scopus 로고
    • Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety
    • Burgin, A.B. et al. Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety. Nat. Biotechnol. 28, 63-70 (2010).
    • (2010) Nat. Biotechnol. , vol.28 , pp. 63-70
    • Burgin, A.B.1
  • 40
    • 0037187646 scopus 로고    scopus 로고
    • Neurobiology of depression
    • Nestler, E.J. et al. Neurobiology of depression. Neuron 34, 13-25 (2002).
    • (2002) Neuron , vol.34 , pp. 13-25
    • Nestler, E.J.1
  • 41
    • 0032944684 scopus 로고    scopus 로고
    • Reciprocal limbic-cortical function and negative mood: Converging PET fndings in depression and normal sadness
    • Mayberg, H.S. et al. Reciprocal limbic-cortical function and negative mood: converging PET fndings in depression and normal sadness. Am. J. Psychiatry 156, 675-682 (1999).
    • (1999) Am. J. Psychiatry , vol.156 , pp. 675-682
    • Mayberg, H.S.1
  • 42
    • 84861541094 scopus 로고    scopus 로고
    • Identifcation of the cortical neurons that mediate antidepressant responses
    • Schmidt, E.F. et al. Identifcation of the cortical neurons that mediate antidepressant responses. Cell 149, 1152-1163 (2012).
    • (2012) Cell , vol.149 , pp. 1152-1163
    • Schmidt, E.F.1
  • 43
    • 84863968495 scopus 로고    scopus 로고
    • Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior
    • Warner-Schmidt, J.L. et al. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proc. Natl. Acad. Sci. USA 109, 11360-11365 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 11360-11365
    • Warner-Schmidt, J.L.1
  • 44
    • 0035868898 scopus 로고    scopus 로고
    • Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
    • Bibb, J.A. et al. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature 410, 376-380 (2001).
    • (2001) Nature , vol.410 , pp. 376-380
    • Bibb, J.A.1
  • 45
    • 36348980553 scopus 로고    scopus 로고
    • Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability
    • Benavides, D.R. et al. Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability. J. Neurosci. 27, 12967-12976 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 12967-12976
    • Benavides, D.R.1
  • 46
    • 77956314453 scopus 로고    scopus 로고
    • CDK5 serves as a major control point in neurotransmitter release
    • Kim, S.H. & Ryan, T.A. CDK5 serves as a major control point in neurotransmitter release. Neuron 67, 797-809 (2010).
    • (2010) Neuron , vol.67 , pp. 797-809
    • Kim, S.H.1    Ryan, T.A.2
  • 47
    • 0042490494 scopus 로고    scopus 로고
    • Cdk5 is essential for synaptic vesicle endocytosis
    • Tan, T.C. et al. Cdk5 is essential for synaptic vesicle endocytosis. Nat. Cell Biol. 5, 701-710 (2003).
    • (2003) Nat. Cell Biol. , vol.5 , pp. 701-710
    • Tan, T.C.1
  • 48
    • 84865323073 scopus 로고    scopus 로고
    • Comparison of cAMP-specifc phosphodiesterase mRNAs distribution in mouse and rat brain
    • Johansson, E.M., Reyes-Irisarri, E. & Mengod, G. Comparison of cAMP-specifc phosphodiesterase mRNAs distribution in mouse and rat brain. Neurosci. Lett. 525, 1-6 (2012).
    • (2012) Neurosci. Lett. , vol.525 , pp. 1-6
    • Johansson, E.M.1    Reyes-Irisarri, E.2    Mengod, G.3
  • 49
    • 84863203834 scopus 로고    scopus 로고
    • Targeting the glutamatergic system to treat major depressive disorder: Rationale and progress to date
    • Mathews, D.C., Henter, I.D. & Zarate, C.A. Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date. Drugs 72, 1313-1333 (2012).
    • (2012) Drugs , vol.72 , pp. 1313-1333
    • Mathews, D.C.1    Henter, I.D.2    Zarate, C.A.3
  • 50
    • 79959542106 scopus 로고    scopus 로고
    • Rodent models of depression: Forced swim and tail suspension behavioral despair tests in rats and mice
    • Castagne, V., Moser, P., Roux, S. & Porsolt, R.D. Rodent models of depression: forced swim and tail suspension behavioral despair tests in rats and mice. Curr. Protoc. Neurosci. 8.8, 10A (2011).
    • (2011) Curr. Protoc. Neurosci. , vol.8 , Issue.8 , pp. 10A
    • Castagne, V.1    Moser, P.2    Roux, S.3    Porsolt, R.D.4
  • 51
    • 80053589736 scopus 로고    scopus 로고
    • A standardized protocol for repeated social defeat stress in mice
    • Golden, S.A., Covington, H.E. III., Berton, O. & Russo, S.J. A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 6, 1183-1191 (2011).
    • (2011) Nat. Protoc. , vol.6 , pp. 1183-1191
    • Golden, S.A.1    Covington, H.E.2    Berton, O.3    Russo, S.J.4
  • 52
    • 0023636527 scopus 로고
    • Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
    • Willner, P., Towell, A., Sampson, D., Sophokleous, S. & Muscat, R. Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berl.) 93, 358-364 (1987).
    • (1987) Psychopharmacology (Berl.) , vol.93 , pp. 358-364
    • Willner, P.1    Towell, A.2    Sampson, D.3    Sophokleous, S.4    Muscat, R.5
  • 53
    • 84863284778 scopus 로고    scopus 로고
    • Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex
    • Yuen, E.Y. et al. Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex. Neuron 73, 962-977 (2012).
    • (2012) Neuron , vol.73 , pp. 962-977
    • Yuen, E.Y.1
  • 54
    • 0030831116 scopus 로고    scopus 로고
    • Bidirectional regulation of DARPP-32 phosphorylation by dopamine
    • Nishi, A., Snyder, G.L. & Greengard, P. Bidirectional regulation of DARPP-32 phosphorylation by dopamine. J. Neurosci. 17, 8147-8155 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 8147-8155
    • Nishi, A.1    Snyder, G.L.2    Greengard, P.3
  • 55
    • 54849409586 scopus 로고    scopus 로고
    • Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum
    • Nishi, A. et al. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J. Neurosci. 28, 10460-10471 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10460-10471
    • Nishi, A.1
  • 56
    • 58149149970 scopus 로고    scopus 로고
    • Parkin defciency increases vulnerability to infammation-related nigral degeneration
    • Frank-Cannon, T.C. et al. Parkin defciency increases vulnerability to infammation-related nigral degeneration. J. Neurosci. 28, 10825-10834 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10825-10834
    • Frank-Cannon, T.C.1
  • 57
    • 0019015257 scopus 로고
    • A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes
    • Marchmont, R.J. & Houslay, M.D. A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes. Biochem. J. 187, 381-392 (1980).
    • (1980) Biochem. J. , vol.187 , pp. 381-392
    • Marchmont, R.J.1    Houslay, M.D.2
  • 58
    • 0028036970 scopus 로고
    • Identifcation of two splice variant forms of type-IVB cyclic AMP phosphodiesterase DPD (rPDE-IVB1) and PDE-4 (rPDE-IVB2) in brain: Selective localization in membrane and cytosolic compartments and differential expression in various brain regions
    • Lobban, M., Shakur, Y., Beattie, J. & Houslay, M.D. Identifcation of two splice variant forms of type-IVB cyclic AMP phosphodiesterase, DPD (rPDE-IVB1) and PDE-4 (rPDE-IVB2) in brain: selective localization in membrane and cytosolic compartments and differential expression in various brain regions. Biochem. J. 304, 399-406 (1994).
    • (1994) Biochem. J. , vol.304 , pp. 399-406
    • Lobban, M.1    Shakur, Y.2    Beattie, J.3    Houslay, M.D.4
  • 59
    • 34249861932 scopus 로고    scopus 로고
    • Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
    • Jiang, L.I. et al. Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway. J. Biol. Chem. 282, 10576-10584 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 10576-10584
    • Jiang, L.I.1
  • 60
    • 34548389858 scopus 로고    scopus 로고
    • Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels
    • Murdoch, H. et al. Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. J. Neurosci. 27, 9513-9524 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 9513-9524
    • Murdoch, H.1
  • 61
    • 0042563232 scopus 로고    scopus 로고
    • Capillary high-performance liquid chromatography/mass spectrometric analysis of proteins from affnity-purifed plasma membrane
    • Zhao, Y., Zhang, W. & White, M.A. Capillary high-performance liquid chromatography/mass spectrometric analysis of proteins from affnity-purifed plasma membrane. Anal. Chem. 75, 3751-3757 (2003).
    • (2003) Anal. Chem. , vol.75 , pp. 3751-3757
    • Zhao, Y.1    Zhang, W.2    White, M.A.3


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