UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE): A master regulator of sialic acid synthesis

Topics in Current Chemistry

Volumn 366, Issue , 2015, Pages 97-138

  Hinderlich, Stephan ^a   Weidemann, Wenke ^b   Yardeni, Tal ^c,d   Horstkorte, Rüdiger ^b   Huizing, Marjan ^c  

^a UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Bifunctional enzyme; GNE myopathy; GNE opathy; N Acetylneuraminic acid biosynthesis; Sialuria; Vertebrates

Indexed keywords

CYTIDINE PHOSPHATE N ACETYLNEURAMINIC ACID; MULTIENZYME COMPLEX; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE - N-ACETYLMANNOSAMINE KINASE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

ANIMAL; CHEMISTRY; DISEASE MODEL; DISTAL MYOPATHY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PROTEIN QUATERNARY STRUCTURE; REGULATOR GENE; SIALIC ACID STORAGE DISEASE; TRANSGENIC MOUSE;

ANIMALS; CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID; DISEASE MODELS, ANIMAL; DISTAL MYOPATHIES; GENE EXPRESSION REGULATION; GENES, REGULATOR; HUMANS; MICE; MICE, TRANSGENIC; MULTIENZYME COMPLEXES; MUTATION; PROTEIN STRUCTURE, QUATERNARY; SIALIC ACID STORAGE DISEASE; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

EID: 84938360410     PISSN: 03401022     EISSN: None     Source Type: Book Series    
DOI: 10.1007/128_2013_464     Document Type: Article

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