메뉴 건너뛰기




Volumn 96, Issue 4, 2015, Pages 337-348

Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts

Author keywords

Chronic low grade inflammation; Flavonoid; I B ; SASP; Senescence

Indexed keywords

BLEOMYCIN; CCL8 PROTEIN, HUMAN; CXCL1 CHEMOKINE; FLAVONOID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B; INTERLEUKIN DERIVATIVE; MONOCYTE CHEMOTACTIC PROTEIN 2; NFKBIZ PROTEIN, HUMAN; NUCLEAR PROTEIN; STROMELYSIN;

EID: 84938291358     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.06.013     Document Type: Article
Times cited : (141)

References (44)
  • 1
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • L. Hayflick The limited in vitro lifetime of human diploid cell strains Exp. Cell Res. 37 1965 614 636
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 2
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • J. Campisi Aging, cellular senescence, and cancer Annu. Rev. Physiol. 75 2013 685 705
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 685-705
    • Campisi, J.1
  • 3
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • F. Rodier, and J. Campisi Four faces of cellular senescence J. Cell Biol. 192 2011 547 556
    • (2011) J. Cell Biol. , vol.192 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 4
    • 84906847476 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotype and its possible role in chronic obstructive pulmonary disease
    • M. Kumar, W. Seeger, and R. Voswinckel Senescence-associated secretory phenotype and its possible role in chronic obstructive pulmonary disease Am. J. Respir. Cell Mol. Biol. 51 2014 323 333
    • (2014) Am. J. Respir. Cell Mol. Biol. , vol.51 , pp. 323-333
    • Kumar, M.1    Seeger, W.2    Voswinckel, R.3
  • 5
  • 6
    • 80855128461 scopus 로고    scopus 로고
    • Cellular senescence: a link between cancer and age-related degenerative disease?
    • J. Campisi, J.K. Andersen, P. Kapahi, and S. Melov Cellular senescence: a link between cancer and age-related degenerative disease? Semin. Cancer Biol. 21 2011 354 359
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 354-359
    • Campisi, J.1    Andersen, J.K.2    Kapahi, P.3    Melov, S.4
  • 7
    • 84894102511 scopus 로고    scopus 로고
    • Enhanced proinflammatory state and autoimmune activation: a breakthrough to understanding chronic diseases
    • A. Onat, and G. Can Enhanced proinflammatory state and autoimmune activation: a breakthrough to understanding chronic diseases Curr. Pharm. Des. 20 2014 575 584
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 575-584
    • Onat, A.1    Can, G.2
  • 8
    • 79955017452 scopus 로고    scopus 로고
    • p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
    • A. Freund, C. Patil, K. Age, and J. Campisi p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype EMBO J. 30 2011 1536 1548
    • (2011) EMBO J. , vol.30 , pp. 1536-1548
    • Freund, A.1    Patil, C.2    Age, K.3    Campisi, J.4
  • 9
    • 84856209016 scopus 로고    scopus 로고
    • Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
    • A. Salminen, A. Kauppinen, and K. Kaarniranta Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP) Cell. Signal. 24 2012 835 845
    • (2012) Cell. Signal. , vol.24 , pp. 835-845
    • Salminen, A.1    Kauppinen, A.2    Kaarniranta, K.3
  • 10
    • 84901649819 scopus 로고    scopus 로고
    • Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation
    • P. Wang, L. Han, H. Shen, P. Wang, C. Lv, G. Zhao, and et al. Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation Proc. Natl. Acad. Sci. U. S. A. 111 2014 7683 7688
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 7683-7688
    • Wang, P.1    Han, L.2    Shen, H.3    Wang, P.4    Lv, C.5    Zhao, G.6
  • 11
    • 80054789761 scopus 로고    scopus 로고
    • Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity
    • Y. Chien, C. Scuoppo, X. Wang, X. Fang, B. Balgley, J.E. Bolden, and et al. Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity Genes Dev. 25 2011 2125 2136
    • (2011) Genes Dev. , vol.25 , pp. 2125-2136
    • Chien, Y.1    Scuoppo, C.2    Wang, X.3    Fang, X.4    Balgley, B.5    Bolden, J.E.6
  • 12
    • 70350125106 scopus 로고    scopus 로고
    • Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
    • A.V. Orjalo, D. Bhaumik, B.K. Gengler, G.K. Scott, and J. Campisi Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network Proc. Natl. Acad. Sci. U. S. A. 106 2009 17031 17036
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 17031-17036
    • Orjalo, A.V.1    Bhaumik, D.2    Gengler, B.K.3    Scott, G.K.4    Campisi, J.5
  • 13
    • 84881278255 scopus 로고    scopus 로고
    • C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβ
    • C.J. Huggins, R. Malik, S. Lee, J. Salotti, S. Thomas, N. Martin, and et al. C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβ Mol. Cell. Biol. 33 2013 3242 3258
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 3242-3258
    • Huggins, C.J.1    Malik, R.2    Lee, S.3    Salotti, J.4    Thomas, S.5    Martin, N.6
  • 14
    • 84883444868 scopus 로고    scopus 로고
    • IκBζ is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence
    • E. Alexander, D.G. Hildebrand, A. Kriebs, K. Obermayer, M. Manz, O. Rothfuss, and et al. IκBζ is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence J. Cell Sci. 126 2013 3738 3745
    • (2013) J. Cell Sci. , vol.126 , pp. 3738-3745
    • Alexander, E.1    Hildebrand, D.G.2    Kriebs, A.3    Obermayer, K.4    Manz, M.5    Rothfuss, O.6
  • 15
    • 14844293877 scopus 로고    scopus 로고
    • Positive and negative regulation of nuclear factor-κB-mediated transcription by IκB-ζ, an inducible nuclear protein
    • M. Motoyama, S. Yamazaki, A. Eto-Kimura, K. Takeshige, and T. Muta Positive and negative regulation of nuclear factor-κB-mediated transcription by IκB-ζ, an inducible nuclear protein J. Biol. Chem. 280 2005 7444 7451
    • (2005) J. Biol. Chem. , vol.280 , pp. 7444-7451
    • Motoyama, M.1    Yamazaki, S.2    Eto-Kimura, A.3    Takeshige, K.4    Muta, T.5
  • 17
    • 34547467781 scopus 로고    scopus 로고
    • Crucial roles of binding sites for NF-κB and C/EBPs in IκB-ζ-mediated transcriptional activation
    • S. Matsuo, S. Yamazaki, K. Takeshige, and T. Muta Crucial roles of binding sites for NF-κB and C/EBPs in IκB-ζ-mediated transcriptional activation Biochem. J. 405 2007 605 615
    • (2007) Biochem. J. , vol.405 , pp. 605-615
    • Matsuo, S.1    Yamazaki, S.2    Takeshige, K.3    Muta, T.4
  • 18
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer
    • E. Middleton Jr., C. Kandaswami, and T.C. Theoharides The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Pharmacol. Rev. 52 2000 673 751
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 19
    • 77956650041 scopus 로고    scopus 로고
    • Luteolin enhances insulin sensitivity via activation of PPARγ transcriptional activity in adipocytes
    • L. Ding, D. Jin, and X. Chen Luteolin enhances insulin sensitivity via activation of PPARγ transcriptional activity in adipocytes J. Nutr. Biochem. 21 2010 941 947
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 941-947
    • Ding, L.1    Jin, D.2    Chen, X.3
  • 20
    • 84861865625 scopus 로고    scopus 로고
    • Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment
    • A. Csiszar, D. Sosnowska, M. Wang, E.G. Lakatta, W.E. Sonntag, and Z. Ungvari Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment J. Gerontol. A: Biol. Sci. Med. Sci. 67 2012 811 820
    • (2012) J. Gerontol. A: Biol. Sci. Med. Sci. , vol.67 , pp. 811-820
    • Csiszar, A.1    Sosnowska, D.2    Wang, M.3    Lakatta, E.G.4    Sonntag, W.E.5    Ungvari, Z.6
  • 21
    • 10944235044 scopus 로고    scopus 로고
    • Anti-inflammatory plant flavonoids and cellular action mechanisms
    • H.P. Kim, K.H. Son, H.W. Chang, and S.S. Kang Anti-inflammatory plant flavonoids and cellular action mechanisms J. Pharmacol. Sci. 96 2004 229 245
    • (2004) J. Pharmacol. Sci. , vol.96 , pp. 229-245
    • Kim, H.P.1    Son, K.H.2    Chang, H.W.3    Kang, S.S.4
  • 22
    • 84875145418 scopus 로고    scopus 로고
    • Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts
    • V. Pitozzi, A. Mocali, A. Laurenzana, E. Giannoni, I. Cifola, C. Battaglia, and et al. Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts J. Gerontol. A: Biol. Sci. Med. Sci. 68 2013 371 381
    • (2013) J. Gerontol. A: Biol. Sci. Med. Sci. , vol.68 , pp. 371-381
    • Pitozzi, V.1    Mocali, A.2    Laurenzana, A.3    Giannoni, E.4    Cifola, I.5    Battaglia, C.6
  • 23
    • 77953019948 scopus 로고    scopus 로고
    • Kaempferol modulates pro-inflammatory NF-κB activation by suppressing advanced glycation endproducts-induced NADPH oxidase
    • J.M. Kim, E.K. Lee, D.H. Kim, B.P. Yu, and H.Y. Chung Kaempferol modulates pro-inflammatory NF-κB activation by suppressing advanced glycation endproducts-induced NADPH oxidase Age (Dordr.) 32 2010 197 208
    • (2010) Age (Dordr.) , vol.32 , pp. 197-208
    • Kim, J.M.1    Lee, E.K.2    Kim, D.H.3    Yu, B.P.4    Chung, H.Y.5
  • 24
    • 84861455323 scopus 로고    scopus 로고
    • PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney
    • H.A. Lim, E.K. Lee, J.M. Kim, M.H. Park, D.H. Kim, Y.J. Choi, and et al. PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney Biogerontology 13 2012 133 145
    • (2012) Biogerontology , vol.13 , pp. 133-145
    • Lim, H.A.1    Lee, E.K.2    Kim, J.M.3    Park, M.H.4    Kim, D.H.5    Choi, Y.J.6
  • 25
    • 0033071142 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants
    • K.M. You, H.G. Jong, and H.P. Kim Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants Arch. Pharm. Res. 22 1999 18 24
    • (1999) Arch. Pharm. Res. , vol.22 , pp. 18-24
    • You, K.M.1    Jong, H.G.2    Kim, H.P.3
  • 26
    • 30444451470 scopus 로고    scopus 로고
    • Synthesis and PGE2 inhibitory activity of 5,7-dihydroxyflavones and their O-methylated flavone analogs
    • T.T. Dao, Y.S. Chi, J. Kim, H.P. Kim, S. Kim, and H. Park Synthesis and PGE2 inhibitory activity of 5,7-dihydroxyflavones and their O-methylated flavone analogs Arch. Pharm. Res. 26 2003 345 350
    • (2003) Arch. Pharm. Res. , vol.26 , pp. 345-350
    • Dao, T.T.1    Chi, Y.S.2    Kim, J.3    Kim, H.P.4    Kim, S.5    Park, H.6
  • 27
    • 80052918619 scopus 로고    scopus 로고
    • A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production
    • H. Che, H. Lim, H.P. Kim, and H. Park A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production Eur. J. Med. Chem. 46 2011 4657 4660
    • (2011) Eur. J. Med. Chem. , vol.46 , pp. 4657-4660
    • Che, H.1    Lim, H.2    Kim, H.P.3    Park, H.4
  • 28
    • 84864010194 scopus 로고    scopus 로고
    • Glucocorticoids suppress selected components of the senescence-associated secretory phenotype
    • R.M. Laberge, L. Zhou, M.R. Sarantos, F. Rodier, A. Freund, P.L. de Keizer, and et al. Glucocorticoids suppress selected components of the senescence-associated secretory phenotype Aging Cell 11 2012 569 578
    • (2012) Aging Cell , vol.11 , pp. 569-578
    • Laberge, R.M.1    Zhou, L.2    Sarantos, M.R.3    Rodier, F.4    Freund, A.5    De Keizer, P.L.6
  • 29
    • 84892406525 scopus 로고    scopus 로고
    • Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation
    • J.H. Lee, H. Lim, O. Shehzad, Y.S. Kim, and H.P. Kim Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation Eur. J. Pharmacol. 724 2014 145 151
    • (2014) Eur. J. Pharmacol. , vol.724 , pp. 145-151
    • Lee, J.H.1    Lim, H.2    Shehzad, O.3    Kim, Y.S.4    Kim, H.P.5
  • 30
    • 84863208596 scopus 로고    scopus 로고
    • SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells
    • C. Canino, F. Mori, A. Cambria, A. Diamantini, S. Germoni, G. Alessandrini, and et al. SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells Oncogene 31 2012 3148 3163
    • (2012) Oncogene , vol.31 , pp. 3148-3163
    • Canino, C.1    Mori, F.2    Cambria, A.3    Diamantini, A.4    Germoni, S.5    Alessandrini, G.6
  • 31
    • 25644444396 scopus 로고    scopus 로고
    • Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2′,4′,7-trimethoxyflavone and cellular action mechanism
    • C.K. Han, M.J. Son, H.W. Chang, Y.S. Chi, H. Park, and H.P. Kim Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2′,4′,7-trimethoxyflavone and cellular action mechanism Biol. Pharm. Bull. 28 2005 1366 1370
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 1366-1370
    • Han, C.K.1    Son, M.J.2    Chang, H.W.3    Chi, Y.S.4    Park, H.5    Kim, H.P.6
  • 32
    • 80755189987 scopus 로고    scopus 로고
    • New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone
    • H. Lim, J.H. Jin, H. Park, and H.P. Kim New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone Eur. J. Pharmacol. 670 2011 617 622
    • (2011) Eur. J. Pharmacol. , vol.670 , pp. 617-622
    • Lim, H.1    Jin, J.H.2    Park, H.3    Kim, H.P.4
  • 33
    • 68249096784 scopus 로고    scopus 로고
    • Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
    • F. Rodier, J.P. Coppé, C.K. Patil, W.A. Hoeijmakers, D.P. Muñoz, S.R. Raza, and et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion Nat. Cell Biol. 11 2009 973 979
    • (2009) Nat. Cell Biol. , vol.11 , pp. 973-979
    • Rodier, F.1    Coppé, J.P.2    Patil, C.K.3    Hoeijmakers, W.A.4    Muñoz, D.P.5    Raza, S.R.6
  • 34
    • 84877822086 scopus 로고    scopus 로고
    • Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation
    • O. Moiseeva, X. Deschênes-Simard, E. St-Germain, S. Igelmann, G. Huot, A.E. Cadar, and et al. Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation Aging Cell 12 2013 489 498
    • (2013) Aging Cell , vol.12 , pp. 489-498
    • Moiseeva, O.1    Deschênes-Simard, X.2    St-Germain, E.3    Igelmann, S.4    Huot, G.5    Cadar, A.E.6
  • 36
    • 84855470274 scopus 로고    scopus 로고
    • Identification of interleukin-1 receptor-associated kinase 1 as a critical component that induces post-transcriptional activation of IκB-ζ
    • T. Ohba, Y. Ariga, T. Maruyama, N.K. Truong, J. Inoue, and T. Muta Identification of interleukin-1 receptor-associated kinase 1 as a critical component that induces post-transcriptional activation of IκB-ζ FEBS J. 279 2012 211 222
    • (2012) FEBS J. , vol.279 , pp. 211-222
    • Ohba, T.1    Ariga, Y.2    Maruyama, T.3    Truong, N.K.4    Inoue, J.5    Muta, T.6
  • 37
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • J.A. Baur, K.J. Pearson, N.L. Price, H.A. Jamieson, C. Lerin, A. Kalra, and et al. Resveratrol improves health and survival of mice on a high-calorie diet Nature 444 2006 337 342
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5    Kalra, A.6
  • 38
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • J.G. Wood, B. Rogina, S. Lavu, K. Howitz, S.L. Helfand, M. Tatar, and et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans Nature 430 2004 686 689
    • (2004) Nature , vol.430 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5    Tatar, M.6
  • 39
    • 67649518873 scopus 로고    scopus 로고
    • The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-κB via nuclear factor-inducing kinase/IκB kinase and mitogen-activated protein kinase pathways
    • M.J. Park, E.K. Lee, H.S. Heo, M.S. Kim, B. Sung, M.K. Kim, and et al. The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-κB via nuclear factor-inducing kinase/IκB kinase and mitogen-activated protein kinase pathways J. Med. Food 12 2009 351 358
    • (2009) J. Med. Food , vol.12 , pp. 351-358
    • Park, M.J.1    Lee, E.K.2    Heo, H.S.3    Kim, M.S.4    Sung, B.5    Kim, M.K.6
  • 40
    • 9744242794 scopus 로고    scopus 로고
    • Dietary flavonoids and cancer risk: evidence from human population studies
    • M.L. Neuhouser Dietary flavonoids and cancer risk: evidence from human population studies Nutr. Cancer 50 2004 1 7
    • (2004) Nutr. Cancer , vol.50 , pp. 1-7
    • Neuhouser, M.L.1
  • 44
    • 84883287472 scopus 로고    scopus 로고
    • Higher dietary flavonol intake is associated with lower incidence of type 2 diabetes
    • P.F. Jacques, A. Cassidy, G. Rogers, J.J. Peterson, J.B. Meigs, and J.T. Dwyer Higher dietary flavonol intake is associated with lower incidence of type 2 diabetes J. Nutr. 143 2013 1474 1480
    • (2013) J. Nutr. , vol.143 , pp. 1474-1480
    • Jacques, P.F.1    Cassidy, A.2    Rogers, G.3    Peterson, J.J.4    Meigs, J.B.5    Dwyer, J.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.