메뉴 건너뛰기




Volumn 670, Issue 2-3, 2011, Pages 617-622

New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine- 4yl)flavone

Author keywords

5,7 Dihydroxy 8 (pyridine 4yl)flavone; Anti inflammation; Cyclooxygenase; Flavonoid; Nitric oxide synthase

Indexed keywords

5,7 DIHYDROXY 8 (PYRIDINE 4YL)FLAVONE; C 721; CYCLOOXYGENASE 2; FLAVONE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE; PREDNISOLONE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WOGONIN;

EID: 80755189987     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.010     Document Type: Article
Times cited : (31)

References (20)
  • 1
    • 0019139791 scopus 로고
    • Flavonoids and related compounds as inhibitors of arachidonic acid peroxidation
    • DOI 10.1016/0090-6980(80)90103-3
    • J. Bauman, F.V. Bruchhausen, and G. Wurm Flavonoids and related compounds as inhibitors of arachidonic acid peroxidation Prostaglandins 20 1980 627 639 (Pubitemid 11176169)
    • (1980) Prostaglandins , vol.20 , Issue.4 , pp. 627-639
    • Baumann, J.1    Von Bruchhausen, F.2    Wurm, G.3
  • 3
    • 0034213030 scopus 로고    scopus 로고
    • Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-κB activation
    • Y.C. Chen, L.L. Yang, and T.J.F. Lee Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-κB activation Biochem. Pharmacol. 59 2000 1445 1457
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1445-1457
    • Chen, Y.C.1    Yang, L.L.2    Lee, T.J.F.3
  • 4
    • 0035873932 scopus 로고    scopus 로고
    • Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxgenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells
    • Y.S. Chi, B.S. Cheon, and H.P. Kim Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxgenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells Biochem. Pharmacol. 61 2001 1195 1203
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 1195-1203
    • Chi, Y.S.1    Cheon, B.S.2    Kim, H.P.3
  • 6
    • 1242339553 scopus 로고    scopus 로고
    • Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives
    • DOI 10.1016/j.bmcl.2003.12.087
    • T.T. Dao, Y.S. Chi, J. Kim, H.P. Kim, S. Kim, and H. Park Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives Bioorg. Med. Chem. Lett. 14 2004 1165 1167 (Pubitemid 38229848)
    • (2004) Bioorganic and Medicinal Chemistry Letters , vol.14 , Issue.5 , pp. 1165-1167
    • Dao, T.T.1    Chi, Y.S.2    Kim, J.3    Kim, H.P.4    Kim, S.5    Park, H.6
  • 10
    • 0020626421 scopus 로고
    • Flavonoids, a class of natural products of high pharmacological potency
    • DOI 10.1016/0006-2952(83)90262-9
    • B. Havsteen Flavonoids, a class of natural products of high pharmacological potency Biochem. Pharmacol. 32 1983 1141 1148 (Pubitemid 13135620)
    • (1983) Biochemical Pharmacology , vol.32 , Issue.7 , pp. 1141-1148
    • Havsteen, B.1
  • 11
    • 0032814249 scopus 로고    scopus 로고
    • Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships
    • DOI 10.1016/S0006-2952(99)00160-4, PII S0006295299001604
    • H.K. Kim, B.S. Cheon, Y.H. Kim, S.Y. Kim, and H.P. Kim Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structural-activity relationships Biochem. Pharmacol. 58 1999 759 765 (Pubitemid 29329524)
    • (1999) Biochemical Pharmacology , vol.58 , Issue.5 , pp. 759-765
    • Kim, H.K.1    Cheon, B.S.2    Kim, Y.H.3    Kim, S.Y.4    Kim, H.P.5
  • 12
    • 10944235044 scopus 로고    scopus 로고
    • Anti-inflammatory plant flavonoids and cellular action mechanisms
    • DOI 10.1254/jphs.CRJ04003X
    • H.P. Kim, K.H. Son, H.W. Chang, and S.S. Kang Anti-inflammatory plant flavonoids and cellular action mechanisms J. Pharmacol. Sci. 96 2004 229 245 (Pubitemid 40013328)
    • (2004) Journal of Pharmacological Sciences , vol.96 , Issue.3 , pp. 229-245
    • Kim, H.P.1    Son, K.H.2    Chang, H.W.3    Kang, S.S.4
  • 13
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • DOI 10.1093/carcin/20.10.1945
    • Y.-C. Liang, Y.-T. Huang, S.-H. Tsai, S.-Y. Shiau, C.-F. Chen, and J.-K. Lin Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages Carcinogenesis 20 1999 1945 1952 (Pubitemid 29476121)
    • (1999) Carcinogenesis , vol.20 , Issue.10 , pp. 1945-1952
    • Liang, Y.-C.1    Huang, Y.-T.2    Tsai, S.-H.3    Lin-Shiau, S.-Y.4    Chen, C.-F.5    Lin, J.-K.6
  • 14
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • E. Middleton, C. Kandaswami, and T.C. Theoharides The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Pharmacol. Rev. 52 2000 673 751
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxic assays
    • T. Mossman Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays J. Immunol. Methods 65 1983 55 63
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mossman, T.1
  • 16
    • 0035846885 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1
    • DOI 10.1016/S0024-3205(00)00999-1, PII S0024320500009991
    • G.M. Raso, R. Meli, G. Di Carlo, M. Pacillio, and R. Di Carlo Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1 Life Sci. 68 2001 921 931 (Pubitemid 32168067)
    • (2001) Life Sciences , vol.68 , Issue.8 , pp. 921-931
    • Raso, G.M.1    Meli, R.2    Di Carlo, G.3    Pacilio, M.4    Di Carlo, R.5
  • 17
    • 0023949959 scopus 로고
    • Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between human and cell-mediated immunity
    • N. Seki, Y. Sudo, T. Yoshioka, S. Sugihara, T. Fujitsu, S. Sakuma, T. Ogawa, T. Hamaoka, H. Senoh, and H. Fujiwara Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between human and cell-mediated immunity J. Immunol. 140 1988 1477 1484
    • (1988) J. Immunol. , vol.140 , pp. 1477-1484
    • Seki, N.1    Sudo, Y.2    Yoshioka, T.3    Sugihara, S.4    Fujitsu, T.5    Sakuma, S.6    Ogawa, T.7    Hamaoka, T.8    Senoh, H.9    Fujiwara, H.10
  • 18
    • 67249094291 scopus 로고
    • Carrageenan-induced edema in the hindpaw of the rats as an assay for anti-inflammatory drugs
    • C.A. Winter, E.A. Risley, and G.W. Nuss Carrageenan-induced edema in the hindpaw of the rats as an assay for anti-inflammatory drugs Proc. Soc. Exp. Biol. Med. 111 1962 544 547
    • (1962) Proc. Soc. Exp. Biol. Med. , vol.111 , pp. 544-547
    • Winter, C.A.1    Risley, E.A.2    Nuss, G.W.3
  • 20
    • 0033071142 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from the several medicinal plants
    • K.M. You, H. Jong, and H.P. Kim Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from the several medicinal plants Arch. Pharm. Res. 22 1999 18 24
    • (1999) Arch. Pharm. Res. , vol.22 , pp. 18-24
    • You, K.M.1    Jong, H.2    Kim, H.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.