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Volumn 7, Issue 1, 2013, Pages 53-58

The role of microRNAs in stemness of cancer stem cells

Author keywords

Cancer; Cancer stem cells; Embryonic stem cells; MicroRNAs; Stemness

Indexed keywords

LONG UNTRANSLATED RNA; MICRORNA; MICRORNA 200; UNTRANSLATED RNA;

EID: 84938213565     PISSN: 19705557     EISSN: 19705565     Source Type: Journal    
DOI: 10.4081/oncol.2013.e8     Document Type: Review
Times cited : (33)

References (106)
  • 1
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994;367:645-8.
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 3
    • 84981839279 scopus 로고    scopus 로고
    • Quantitative studies of autotransplantation of human cancer. Preliminary report
    • Southam CM, Brunschwig A. Quantitative studies of autotransplantation of human cancer. Preliminary report. Cancer 2006;14:971-8.
    • (2006) Cancer , vol.14 , pp. 971-978
    • Southam, C.M.1    Brunschwig, A.2
  • 4
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004;432:396-401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 5
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445:106-10.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 6
    • 34547193404 scopus 로고    scopus 로고
    • Phenotypic characterization of human colorectal cancer stem cells
    • Dalerba P, Dylla SJ, Park IK, et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 2007;104:10158-63.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10158-10163
    • Dalerba, P.1    Dylla, S.J.2    Park, I.K.3
  • 7
    • 33645026803 scopus 로고    scopus 로고
    • Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
    • Patrawala L, Calhoun T, Schneider-Broussard R, et al. Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 2006;25:1696-708.
    • (2006) Oncogene , vol.25 , pp. 1696-1708
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3
  • 8
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells: Lessons from leukemia
    • Wang JC, Dick JE. Cancer stem cells: lessons from leukemia. Trends Cell Biol 2005;15:494-501.
    • (2005) Trends Cell Biol , vol.15 , pp. 494-501
    • Wang, J.C.1    Dick, J.E.2
  • 9
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • Clarke MF, Dick JE, Dirks PB, et al. Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 2006;66:9339-44.
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3
  • 10
    • 28444440238 scopus 로고    scopus 로고
    • Leukemia: Stem cells, maturation arrest, and differentiation therapy
    • Sell S. Leukemia: stem cells, maturation arrest, and differentiation therapy. Stem Cell Rev 2005;1:197-205.
    • (2005) Stem Cell Rev , vol.1 , pp. 197-205
    • Sell, S.1
  • 11
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell S. Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 2004;51:1-28.
    • (2004) Crit Rev Oncol Hematol , vol.51 , pp. 1-28
    • Sell, S.1
  • 12
    • 13844280894 scopus 로고    scopus 로고
    • Oct4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis
    • Tai MH, Chang CC, Kiupel M, et al. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis 2005;26:495-502.
    • (2005) Carcinogenesis , vol.26 , pp. 495-502
    • Tai, M.H.1    Chang, C.C.2    Kiupel, M.3
  • 14
    • 18944375734 scopus 로고    scopus 로고
    • Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
    • Dontu G, Jackson KW, McNicholas E, et al. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res 2004;6:R605-15.
    • (2004) Breast Cancer Res , vol.6 , pp. R605-R615
    • Dontu, G.1    Jackson, K.W.2    McNicholas, E.3
  • 15
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer-role of Notch signalling
    • Farnie G, Clarke RB. Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev 2007;3:169-75.
    • (2007) Stem Cell Rev , vol.3 , pp. 169-175
    • Farnie, G.1    Clarke, R.B.2
  • 16
    • 37549069749 scopus 로고    scopus 로고
    • No place like home: Anatomy and function of the stem cell niche
    • Jones DL, Wagers AJ. No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol 2008;9:11-21.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 11-21
    • Jones, D.L.1    Wagers, A.J.2
  • 17
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer 2008;8:387-98.
    • (2008) Nat Rev Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 18
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID, et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-71.
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3
  • 19
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122:947-56.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 20
    • 84877978530 scopus 로고    scopus 로고
    • Mechanisms and models of somatic cell reprogramming
    • Buganim Y, Faddah DA, Jaenisch R. Mechanisms and models of somatic cell reprogramming. Nat Rev Genet 2013;14:427-39.
    • (2013) Nat Rev Genet , vol.14 , pp. 427-439
    • Buganim, Y.1    Faddah, D.A.2    Jaenisch, R.3
  • 21
    • 84868618042 scopus 로고    scopus 로고
    • Nanog signaling in cancer promotes stem-like phenotype and immune evasion
    • Noh KH, Kim BW, Song KH, et al. Nanog signaling in cancer promotes stem-like phenotype and immune evasion. J Clin Invest 2012;122:4077-93.
    • (2012) J Clin Invest , vol.122 , pp. 4077-4093
    • Noh, K.H.1    Kim, B.W.2    Song, K.H.3
  • 22
    • 84869028375 scopus 로고    scopus 로고
    • Self-renewal and pluripotency acquired through somatic reprogramming to human cancer stem cells
    • Nagata S, Hirano K, Kanemori M, et al. Self-renewal and pluripotency acquired through somatic reprogramming to human cancer stem cells. PLoS One 2012;7:e48699.
    • (2012) PLoS One , vol.7 , pp. e48699
    • Nagata, S.1    Hirano, K.2    Kanemori, M.3
  • 23
    • 70349338871 scopus 로고    scopus 로고
    • Stem cells, stress, metabolism and cancer: A drama in two Octs
    • Kang J, Shakya A, Tantin D. Stem cells, stress, metabolism and cancer: a drama in two Octs. Trends Biochem Sci 2009;34:491-9.
    • (2009) Trends Biochem Sci , vol.34 , pp. 491-499
    • Kang, J.1    Shakya, A.2    Tantin, D.3
  • 24
    • 84866702740 scopus 로고    scopus 로고
    • Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms
    • Ibrahim EE, Babaei-Jadidi R, Saadeddin A, et al. Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms. Stem Cells 2012;30:2076-87.
    • (2012) Stem Cells , vol.30 , pp. 2076-2087
    • Ibrahim, E.E.1    Babaei-Jadidi, R.2    Saadeddin, A.3
  • 25
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • Huarte M, Guttman M, Feldser D, et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 2010;142:409-19.
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1    Guttman, M.2    Feldser, D.3
  • 26
    • 78651390167 scopus 로고    scopus 로고
    • Long intergenic noncoding RNAs: New links in cancer progression
    • Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Res 2011;71:3-7.
    • (2011) Cancer Res , vol.71 , pp. 3-7
    • Tsai, M.C.1    Spitale, R.C.2    Chang, H.Y.3
  • 27
    • 78651397147 scopus 로고    scopus 로고
    • Large non-coding RNAs: Missing links in cancer?
    • Huarte M, Rinn JL. Large non-coding RNAs: missing links in cancer? Hum Mol Genet 2010;19:R152-61.
    • (2010) Hum Mol Genet , vol.19 , pp. R152-R161
    • Huarte, M.1    Rinn, J.L.2
  • 28
    • 79953888460 scopus 로고    scopus 로고
    • The functional role of long non-coding RNA in human carcinomas
    • Gibb EA, Brown CJ, Lam WL. The functional role of long non-coding RNA in human carcinomas. Mol Cancer 2011;10:38.
    • (2011) Mol Cancer , vol.10 , pp. 38
    • Gibb, E.A.1    Brown, C.J.2    Lam, W.L.3
  • 29
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993;75:843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 30
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: Understanding the structure and function of small RNAs
    • Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 2007;8:23-36.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 31
    • 33847051277 scopus 로고    scopus 로고
    • Transcriptional activation by small RNA duplexes
    • Rossi JJ. Transcriptional activation by small RNA duplexes. Nat Chem Biol 2007;3:136-7.
    • (2007) Nat Chem Biol , vol.3 , pp. 136-137
    • Rossi, J.J.1
  • 32
    • 84863229533 scopus 로고    scopus 로고
    • Upregulation of Cyclin B1 by miRNA and its implications in cancer
    • Huang V, Place RF, Portnoy V, et al. Upregulation of Cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res 2012;40:1695-707.
    • (2012) Nucleic Acids Res , vol.40 , pp. 1695-1707
    • Huang, V.1    Place, R.F.2    Portnoy, V.3
  • 33
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-66.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 34
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004;101:2999-3004.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 35
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI, et al. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-43.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3
  • 36
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-33.
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 37
    • 27244433702 scopus 로고    scopus 로고
    • Real-time expression profiling of microRNA precursors in human cancer cell lines
    • Jiang J, Lee EJ, Gusev Y, Schmittgen TD. Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res 2005;33:5394-403.
    • (2005) Nucleic Acids Res , vol.33 , pp. 5394-5403
    • Jiang, J.1    Lee, E.J.2    Gusev, Y.3    Schmittgen, T.D.4
  • 38
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002;99:15524-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 39
    • 25444520537 scopus 로고    scopus 로고
    • miR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005;102:13944-9.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 40
    • 51349157982 scopus 로고    scopus 로고
    • The MYCN oncogene is a direct target of MIR-34a
    • Wei JS, Song YK, Durinck S, et al. The MYCN oncogene is a direct target of miR-34a. Oncogene 2008;27:5204-13.
    • (2008) Oncogene , vol.27 , pp. 5204-5213
    • Wei, J.S.1    Song, Y.K.2    Durinck, S.3
  • 41
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • Welch C, Chen Y, Stallings RL. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 2007;26:5017-22.
    • (2007) Oncogene , vol.26 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 42
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
    • Raver-Shapira N, Marciano E, Meiri E, et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Molecular Cell 2007;26:731-43.
    • (2007) Molecular Cell , vol.26 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3
  • 43
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005;65:7065-70.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 44
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki K, Imoto I, Mogi S, et al. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008;68:2094-105.
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3
  • 45
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005;120:635-47.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 46
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 2007;21:1025-30.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 47
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007;67:9762-70.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3
  • 48
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008;9:582-9.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3
  • 49
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang CJ, Chao CH, Xia W, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 2011;13:317-23.
    • (2011) Nat Cell Biol , vol.13 , pp. 317-323
    • Chang, C.J.1    Chao, C.H.2    Xia, W.3
  • 50
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009;138:592-603.
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 51
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009;11:1487-95.
    • (2009) Nat Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3
  • 52
    • 84884988122 scopus 로고    scopus 로고
    • MicroRNA control of mouse and human pluripotent stem cell behavior
    • Greve TS, Judson RL, Blelloch R. microRNA Control of Mouse and Human Pluripotent Stem Cell Behavior. Annu Rev Cell Dev Biol 2013:29:213-39.
    • (2013) Annu Rev Cell Dev Biol , vol.29 , pp. 213-239
    • Greve, T.S.1    Judson, R.L.2    Blelloch, R.3
  • 53
    • 84867740278 scopus 로고    scopus 로고
    • MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics
    • Xia H, Hui KM. MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics. Cancer Gene Ther 2012;19:723-30.
    • (2012) Cancer Gene Ther , vol.19 , pp. 723-730
    • Xia, H.1    Hui, K.M.2
  • 54
    • 84892674951 scopus 로고    scopus 로고
    • MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells
    • Epub ahead of print
    • Ceppi P, Peter ME. MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells. Oncogene 2013. [Epub ahead of print].
    • (2013) Oncogene
    • Ceppi, P.1    Peter, M.E.2
  • 55
    • 79551607574 scopus 로고    scopus 로고
    • DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis
    • Keyes WM, Pecoraro M, Aranda V, et al. DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell 2011;8:164-76.
    • (2011) Cell Stem Cell , vol.8 , pp. 164-176
    • Keyes, W.M.1    Pecoraro, M.2    Aranda, V.3
  • 56
    • 84875968686 scopus 로고    scopus 로고
    • MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of DeltaNP63alpha and promotes mesenchymalto-epithelial transition
    • DeCastro AJ, Dunphy KA, Hutchinson J, et al. MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of DeltaNP63alpha and promotes mesenchymalto-epithelial transition. Cell Death Dis 2013;4:e514.
    • (2013) Cell Death Dis , vol.4 , pp. e514
    • DeCastro, A.J.1    Dunphy, K.A.2    Hutchinson, J.3
  • 57
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • Lin T, Chao C, Saito S, et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 2005;7:165-71.
    • (2005) Nat Cell Biol , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3
  • 58
    • 79951810835 scopus 로고    scopus 로고
    • Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
    • Vallejo DM, Caparros E, Dominguez M. Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. EMBO J 2011;30:756-69.
    • (2011) EMBO J , vol.30 , pp. 756-769
    • Vallejo, D.M.1    Caparros, E.2    Dominguez, M.3
  • 59
    • 84880570961 scopus 로고    scopus 로고
    • MicroRNA-antagonism regulates breast cancer stemness and metastasis via TETFamily-Dependent chromatin remodeling
    • Song SJ, Poliseno L, Song MS, et al. MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TETFamily-Dependent Chromatin Remodeling. Cell 2013;154:311-24.
    • (2013) Cell , vol.154 , pp. 311-324
    • Song, S.J.1    Poliseno, L.2    Song, M.S.3
  • 60
    • 84880571480 scopus 로고    scopus 로고
    • The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation
    • Song SJ, Ito K, Ala U, et al. The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell 2013;13:87-101.
    • (2013) Cell Stem Cell , vol.13 , pp. 87-101
    • Song, S.J.1    Ito, K.2    Ala, U.3
  • 61
    • 84871246002 scopus 로고    scopus 로고
    • The MIR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer
    • Smith AL, Iwanaga R, Drasin DJ, et al. The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. Oncogene 2012;31:5162-71.
    • (2012) Oncogene , vol.31 , pp. 5162-5171
    • Smith, A.L.1    Iwanaga, R.2    Drasin, D.J.3
  • 62
    • 58849163959 scopus 로고    scopus 로고
    • MicroRNAs: Key regulators of stem cells
    • Gangaraju VK, Lin H. MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol 2009;10:116-25.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 116-125
    • Gangaraju, V.K.1    Lin, H.2
  • 64
    • 48449084118 scopus 로고    scopus 로고
    • Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • Marson A, Levine SS, Cole MF, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008;134:521-33.
    • (2008) Cell , vol.134 , pp. 521-533
    • Marson, A.1    Levine, S.S.2    Cole, M.F.3
  • 65
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 2008;40:1478-83.
    • (2008) Nat Genet , vol.40 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.E.4    Baehner, L.5    Blelloch, R.6
  • 66
    • 33846190181 scopus 로고    scopus 로고
    • Tcl1 expression in chronic lymphocytic leukemia is regulated by MIR-29 and MIR-181
    • Pekarsky Y, Santanam U, Cimmino A, et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006;66:11590-3.
    • (2006) Cancer Res , vol.66 , pp. 11590-11593
    • Pekarsky, Y.1    Santanam, U.2    Cimmino, A.3
  • 67
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • Tay Y, Zhang J, Thomson AM, et al. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008;455:1124-8.
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3
  • 68
    • 84866780162 scopus 로고    scopus 로고
    • Molecular roadblocks for cellular reprogramming
    • Vierbuchen T, Wernig M. Molecular roadblocks for cellular reprogramming. Mol Cell 2012;47:827-38.
    • (2012) Mol Cell , vol.47 , pp. 827-838
    • Vierbuchen, T.1    Wernig, M.2
  • 69
    • 79955780736 scopus 로고    scopus 로고
    • Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
    • Subramanyam D, Lamouille S, Judson RL, et al. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat Biotechnol 2011;29:443-8.
    • (2011) Nat Biotechnol , vol.29 , pp. 443-448
    • Subramanyam, D.1    Lamouille, S.2    Judson, R.L.3
  • 70
    • 68049119923 scopus 로고    scopus 로고
    • MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells
    • Sengupta S, Nie J, Wagner RJ, et al. MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells. Stem Cells 2009;27:1524-8.
    • (2009) Stem Cells , vol.27 , pp. 1524-1528
    • Sengupta, S.1    Nie, J.2    Wagner, R.J.3
  • 71
    • 84871586080 scopus 로고    scopus 로고
    • A molecular roadmap of reprogramming somatic cells into iPS cells
    • Polo JM, Anderssen E, Walsh RM, et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 2012;151:1617-32.
    • (2012) Cell , vol.151 , pp. 1617-1632
    • Polo, J.M.1    Anderssen, E.2    Walsh, R.M.3
  • 72
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cellspecific microRNAs promote induced pluripotency
    • Judson RL, Babiarz JE, Venere M, Blelloch R. Embryonic stem cellspecific microRNAs promote induced pluripotency. Nat Biotechnol 2009;27:459-61.
    • (2009) Nat Biotechnol , vol.27 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 73
    • 70350302617 scopus 로고    scopus 로고
    • Myc-regulated microRNAs attenuate embryonic stem cell differentiation
    • Lin CH, Jackson AL, Guo J, et al. Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J 2009;28:3157-70.
    • (2009) EMBO J , vol.28 , pp. 3157-3170
    • Lin, C.H.1    Jackson, A.L.2    Guo, J.3
  • 74
    • 84863732955 scopus 로고    scopus 로고
    • Synergetic cooperation of microRNAs with transcription factors in iPS cell generation
    • Chen J, Wang G, Lu C, et al. Synergetic cooperation of microRNAs with transcription factors in iPS cell generation. PLoS One 2012;7:e40849.
    • (2012) PLoS One , vol.7 , pp. e40849
    • Chen, J.1    Wang, G.2    Lu, C.3
  • 75
    • 82755187396 scopus 로고    scopus 로고
    • The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-Cdependent manner
    • Wang T, Chen K, Zeng X, et al. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-Cdependent manner. Cell Stem Cell 2011;9:575-87.
    • (2011) Cell Stem Cell , vol.9 , pp. 575-587
    • Wang, T.1    Chen, K.2    Zeng, X.3
  • 76
    • 68549118772 scopus 로고    scopus 로고
    • Regulation of 'stemness' and stem cell differentiation by microRNAs
    • Sartipy P, Olsson B, Hyllner J, Synnergren J. Regulation of 'stemness' and stem cell differentiation by microRNAs. IDrugs 2009;12:492-6.
    • (2009) IDrugs , vol.12 , pp. 492-496
    • Sartipy, P.1    Olsson, B.2    Hyllner, J.3    Synnergren, J.4
  • 77
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008;14:818-29.
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 78
    • 79953689605 scopus 로고    scopus 로고
    • Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-Phenotypic cells: Are they cousins or twins?
    • Kong D, Li Y, Wang Z, Sarkar FH. Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins? Cancers (Basel) 2011;3:716-29.
    • (2011) Cancers (Basel) , vol.3 , pp. 716-729
    • Kong, D.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 79
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008;10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 80
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B, et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007;6:1586-93.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3
  • 81
    • 79751473114 scopus 로고    scopus 로고
    • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    • Liu C, Kelnar K, Liu B, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011;17:211-5.
    • (2011) Nat Med , vol.17 , pp. 211-215
    • Liu, C.1    Kelnar, K.2    Liu, B.3
  • 82
    • 84877263242 scopus 로고    scopus 로고
    • A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells
    • Bu P, Chen KY, Chen JH, et al. A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells. Cell Stem Cell 2013;12:602-15.
    • (2013) Cell Stem Cell , vol.12 , pp. 602-615
    • Bu, P.1    Chen, K.Y.2    Chen, J.H.3
  • 83
    • 12944314946 scopus 로고    scopus 로고
    • Allelic losses at 1p36 and 19q13 in gliomas: Correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene
    • Barbashina V, Salazar P, Holland EC, Rosenblum MK, Ladanyi M. Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene. Clin Cancer Res 2005;11:1119-28.
    • (2005) Clin Cancer Res , vol.11 , pp. 1119-1128
    • Barbashina, V.1    Salazar, P.2    Holland, E.C.3    Rosenblum, M.K.4    Ladanyi, M.5
  • 84
    • 80054937128 scopus 로고    scopus 로고
    • CAMTA1 is a novel tumour suppressor regulated by miR-9/9 in glioblastoma stem cells
    • Schraivogel D, Weinmann L, Beier D, et al. CAMTA1 is a novel tumour suppressor regulated by miR-9/9 in glioblastoma stem cells. EMBO J 2011;30:4309-22.
    • (2011) EMBO J , vol.30 , pp. 4309-4322
    • Schraivogel, D.1    Weinmann, L.2    Beier, D.3
  • 85
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A, et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008;68:9125-30.
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3
  • 86
    • 78649681554 scopus 로고    scopus 로고
    • MIR-130b Promotes CD133 (+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
    • Ma S, Tang KH, Chan YP, et al. miR-130b Promotes CD133 (+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell 2010;7:694-707.
    • (2010) Cell Stem Cell , vol.7 , pp. 694-707
    • Ma, S.1    Tang, K.H.2    Chan, Y.P.3
  • 87
    • 79955771439 scopus 로고    scopus 로고
    • MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer
    • Suh SO, Chen Y, Zaman MS, et al. MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis 2011;32:772-8.
    • (2011) Carcinogenesis , vol.32 , pp. 772-778
    • Suh, S.O.1    Chen, Y.2    Zaman, M.S.3
  • 88
    • 78249255491 scopus 로고    scopus 로고
    • FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis
    • Gan B, Lim C, Chu G, et al. FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell 2010;18:472-84.
    • (2010) Cancer Cell , vol.18 , pp. 472-484
    • Gan, B.1    Lim, C.2    Chu, G.3
  • 89
    • 84855389885 scopus 로고    scopus 로고
    • MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFbetaR2) in colon cancer cells
    • Yu Y, Kanwar SS, Patel BB, et al. MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFbetaR2) in colon cancer cells. Carcinogenesis 2012;33:68-76.
    • (2012) Carcinogenesis , vol.33 , pp. 68-76
    • Yu, Y.1    Kanwar, S.S.2    Patel, B.B.3
  • 90
    • 84921754915 scopus 로고    scopus 로고
    • Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer
    • Epub ahead of print
    • Li Q, Yao Y, Eades G, et al. Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer. Oncogene 2013. [Epub ahead of print].
    • (2013) Oncogene
    • Li, Q.1    Yao, Y.2    Eades, G.3
  • 91
    • 77954954098 scopus 로고    scopus 로고
    • MIR-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
    • Yu F, Deng H, Yao H, et al. Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells. Oncogene 2010;29:4194-204.
    • (2010) Oncogene , vol.29 , pp. 4194-4204
    • Yu, F.1    Deng, H.2    Yao, H.3
  • 92
    • 79957613439 scopus 로고    scopus 로고
    • MiR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
    • Hwang-Verslues WW, Chang PH, Wei PC, et al. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene 2011;30:2463-74.
    • (2011) Oncogene , vol.30 , pp. 2463-2474
    • Hwang-Verslues, W.W.1    Chang, P.H.2    Wei, P.C.3
  • 93
    • 84880223123 scopus 로고    scopus 로고
    • The role of MicroRNAs in breast cancer stem cells
    • Schwarzenbacher D, Balic M, Pichler M. The Role of MicroRNAs in Breast Cancer Stem Cells. Int J Mol Sci 2013;14:14712-23.
    • (2013) Int J Mol Sci , vol.14 , pp. 14712-14723
    • Schwarzenbacher, D.1    Balic, M.2    Pichler, M.3
  • 94
    • 55549113152 scopus 로고    scopus 로고
    • MicroRNA expression profile of bronchioalveolar stem cells from mouse lung
    • Qian S, Ding JY, Xie R, et al. MicroRNA expression profile of bronchioalveolar stem cells from mouse lung. Biochem Biophys Res Commun 2008;377:668-73.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 668-673
    • Qian, S.1    Ding, J.Y.2    Xie, R.3
  • 95
    • 52949125268 scopus 로고    scopus 로고
    • MIR-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin SL, Chang DC, Chang-Lin S, et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 2008;14:2115-24.
    • (2008) RNA , vol.14 , pp. 2115-2124
    • Lin, S.L.1    Chang, D.C.2    Chang-Lin, S.3
  • 96
    • 84859177611 scopus 로고    scopus 로고
    • MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer
    • Xu XT, Xu Q, Tong JL, et al. MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer. Br J Cancer 2012;106:1320-30.
    • (2012) Br J Cancer , vol.106 , pp. 1320-1330
    • Xu, X.T.1    Xu, Q.2    Tong, J.L.3
  • 97
    • 0142120587 scopus 로고    scopus 로고
    • Reduced accumulation of specific microRNAs in colorectal neoplasia
    • Michael MZ, Sm OC, van Holst Pellekaan NG, et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 2003;1:882-91.
    • (2003) Mol Cancer Res , vol.1 , pp. 882-891
    • Michael, M.Z.1    Sm, O.C.2    Van Holst Pellekaan, N.G.3
  • 98
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K, et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004;64:3753-6.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 99
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • Szafranska AE, Davison TS, John J, et al. MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 2007;26:4442-52.
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3
  • 100
    • 36849023466 scopus 로고    scopus 로고
    • Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2
    • Park SM, Shell S, Radjabi AR, et al. Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 2007;6:2585-90.
    • (2007) Cell Cycle , vol.6 , pp. 2585-2590
    • Park, S.M.1    Shell, S.2    Radjabi, A.R.3
  • 101
    • 33847748913 scopus 로고    scopus 로고
    • The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
    • Brueckner B, Stresemann C, Kuner R, et al. The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 2007;67:1419-23.
    • (2007) Cancer Res , vol.67 , pp. 1419-1423
    • Brueckner, B.1    Stresemann, C.2    Kuner, R.3
  • 102
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007;131:1109-23.
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 104
    • 77956278708 scopus 로고    scopus 로고
    • Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers
    • Liao JY, Ma LM, Guo YH, et al. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. PLoS One 2010;5:e10563.
    • (2010) PLoS One , vol.5 , pp. e10563
    • Liao, J.Y.1    Ma, L.M.2    Guo, Y.H.3
  • 105
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis ME, Chen ZG, Shin DM. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 2008;7:771-82.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 106
    • 79960530841 scopus 로고    scopus 로고
    • In vivo delivery of RNAi with lipid-based nanoparticles
    • Huang L, Liu Y. In vivo delivery of RNAi with lipid-based nanoparticles. Annu Rev Biomed Eng 2011;13:507-30.
    • (2011) Annu Rev Biomed Eng , vol.13 , pp. 507-530
    • Huang, L.1    Liu, Y.2


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