Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury

Journal of Controlled Release

Volumn 214, Issue , 2015, Pages 112-120

  Nance, Elizabeth ^a   Porambo, Michael ^b   Zhang, Fan ^a,c   Mishra, Manoj K ^a,d   Buelow, Markus ^b   Getzenberg, Rachel ^b   Johnston, Michael ^a,b   Kannan, Rangaramanujam M ^a,b,d   Fatemi, Ali ^a,b   Kannan, Sujatha ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Dendrimer; Ischemia; Microglia; Neonatal; Neuroinflammation; Targeted delivery

Indexed keywords

AMINO ACIDS; BRAIN; DENDRIMERS; DISEASES; DRUG THERAPY; PATHOLOGY;

ISCHEMIA; MICROGLIA; NEONATAL; NEUROINFLAMMATION; TARGETED DELIVERY;

HEALTH RISKS;

ACETYLCYSTEINE; DENDRIMER; POLYAMIDOAMINE; CYTOKINE; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CELL DEATH; CELL DIFFERENTIATION; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG CONJUGATION; IN VIVO STUDY; MICROGLIA; MOUSE; MYELINATION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; SINGLE DRUG DOSE; SYSTEMIC THERAPY; WHITE MATTER INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN; CELL MOTION; CELL PROLIFERATION; CHEMISTRY; DENSITOMETRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; GENETICS; METABOLISM; MYELIN SHEATH; PATHOLOGY; PREGNANCY; WHITE MATTER;

ACETYLCYSTEINE; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BRAIN; BRAIN ISCHEMIA; CELL MOVEMENT; CELL PROLIFERATION; CYTOKINES; DENDRIMERS; DENSITOMETRY; DRUG DELIVERY SYSTEMS; FEMALE; MICE; MICROGLIA; MYELIN SHEATH; OLIGODENDROGLIA; PREGNANCY; RNA; WHITE MATTER;

EID: 84938152502     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.07.009     Document Type: Article

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