Intranasal delivery of HMGB1 siRNA confers target gene knockdown and robust neuroprotection in the postischemic brain

Molecular Therapy

Volumn 20, Issue 4, 2012, Pages 829-839

  Kim, Il Doo ^a   Shin, Joo Hyun ^a   Kim, Seung Woo ^a   Choi, Sunghyun ^b   Ahn, Junseong ^b   Han, Pyung Lim ^c   Park, Jong Sang ^b   Lee, Ja Kyeong ^a  

^a Inha University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DENDRIMER; HIGH MOBILITY GROUP B1 PROTEIN; POLYAMIDOAMINE; SMALL INTERFERING RNA;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORPUS STRIATUM; CYTOPLASM; DRUG MECHANISM; EXCITOTOXICITY; GENE THERAPY; GLIA CELL; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OLFACTORY BULB; PREFRONTAL CORTEX; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

RATTUS;

EID: 84862819673     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.291     Document Type: Article

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