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Volumn 21, Issue 27, 2015, Pages 8238-8248

CREB-binding protein, p300, butyrate, and Wnt signaling in colorectal cancer

Author keywords

Butyrate; Colorectal cancer; CREB binding protein; P300; Stem cells; Wnt

Indexed keywords

BETA CATENIN; BUTYRIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A ASSOCIATED P300 PROTEIN; HISTONE DEACETYLASE INHIBITOR; N BENZYL 1,2,3,4,8,9 HEXAHYDRO 6 (4 HYDROXYBENZYL) 8 (1 NAPHTHYLMETHYL) 4,7 DIOXO 2H PYRAZINO[1,2 A]PYRIMIDINE 1(6H) CARBOXAMIDE; WNT PROTEIN; ANTINEOPLASTIC AGENT; BUTYRIC ACID DERIVATIVE; CREBBP PROTEIN, HUMAN; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF;

EID: 84938149540     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i27.8238     Document Type: Article
Times cited : (46)

References (57)
  • 1
    • 2442637870 scopus 로고    scopus 로고
    • Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate
    • PMID: 15122584
    • Lazarova DL, Bordonaro M, Carbone R, Sartorelli AC. Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate. Int J Cancer 2004; 110: 523-531 [PMID: 15122584 DOI: 10.1002/ijc.20152]
    • (2004) Int J Cancer , vol.110 , pp. 523-531
    • Lazarova, D.L.1    Bordonaro, M.2    Carbone, R.3    Sartorelli, A.C.4
  • 2
    • 34247157352 scopus 로고    scopus 로고
    • The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors
    • PMID: 17359971
    • Bordonaro M, Lazarova DL, Sartorelli AC. The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors. Exp Cell Res 2007; 313: 1652-1666 [PMID: 17359971 DOI: 10.1016/j.yexcr.2007.02.008]
    • (2007) Exp Cell Res , vol.313 , pp. 1652-1666
    • Bordonaro, M.1    Lazarova, D.L.2    Sartorelli, A.C.3
  • 3
    • 0036710163 scopus 로고    scopus 로고
    • Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro
    • PMID: 12204677
    • Richter M, Jurek D, Wrba F, Kaserer K, Wurzer G, Karner-Hanusch J, Marian B. Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro. Eur J Cancer 2002; 38: 1937-1945 [PMID: 12204677 DOI: 10.1016/S0959-8049(02]00158-2]
    • (2002) Eur J Cancer , vol.38 , pp. 1937-1945
    • Richter, M.1    Jurek, D.2    Wrba, F.3    Kaserer, K.4    Wurzer, G.5    Karner-Hanusch, J.6    Marian, B.7
  • 4
    • 27144475265 scopus 로고    scopus 로고
    • The gut fermentation product butyrate, a chemopreventive agent, suppresses glutathione S-transferase theta (hGSTT1) and cell growth more in human colon adenoma (LT97) than tumor (HT29) cells
    • PMID: 16133571
    • Kautenburger T, Beyer-Sehlmeyer G, Festag G, Haag N, Kühler S, Küchler A, Weise A, Marian B, Peters WH, Liehr T, Claussen U, Pool-Zobel BL. The gut fermentation product butyrate, a chemopreventive agent, suppresses glutathione S-transferase theta (hGSTT1) and cell growth more in human colon adenoma (LT97) than tumor (HT29) cells. J Cancer Res Clin Oncol 2005; 131: 692-700 [PMID: 16133571 DOI: 10.1007/s00432-005-0013-4]
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 692-700
    • Kautenburger, T.1    Beyer-Sehlmeyer, G.2    Festag, G.3    Haag, N.4    Kühler, S.5    Küchler, A.6    Weise, A.7    Marian, B.8    Peters, W.H.9    Liehr, T.10    Claussen, U.11    Pool-Zobel, B.L.12
  • 5
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: Migrating cancer stem cells - An integrated concept of malignant tumour progression
    • PMID: 16148886
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer 2005; 5: 744-749 [PMID: 16148886 DOI: 10.1038/nrc1694]
    • (2005) Nat Rev Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 9
    • 0025458150 scopus 로고
    • Mechanisms and experimental and epidemiological evidence relating dietary fibre (non-starch polysaccharides) and starch to protection against large bowel cancer
    • PMID: 2172992
    • Bingham SA. Mechanisms and experimental and epidemiological evidence relating dietary fibre (non-starch polysaccharides) and starch to protection against large bowel cancer. Proc Nutr Soc 1990; 49: 153-171 [PMID: 2172992 DOI: 10.1079/PNS19900021]
    • (1990) Proc Nutr Soc , vol.49 , pp. 153-171
    • Bingham, S.A.1
  • 10
    • 0023276469 scopus 로고
    • Short chain fatty acids in human large intestine, portal, hepatic and venous blood
    • PMID: 3678950
    • Cummings JH, Pomare EW, Branch WJ, Naylor CP, Macfarlane GT. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 1987; 28: 1221-1227 [PMID: 3678950 DOI: 10.1136/gut.28.10.1221]
    • (1987) Gut , vol.28 , pp. 1221-1227
    • Cummings, J.H.1    Pomare, E.W.2    Branch, W.J.3    Naylor, C.P.4    Macfarlane, G.T.5
  • 11
    • 0026495376 scopus 로고
    • Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
    • PMID: 1327519
    • Boffa LC, Lupton JR, Mariani MR, Ceppi M, Newmark HL, Scalmati A, Lipkin M. Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res 1992; 52: 5906-5912 [PMID: 1327519]
    • (1992) Cancer Res , vol.52 , pp. 5906-5912
    • Boffa, L.C.1    Lupton, J.R.2    Mariani, M.R.3    Ceppi, M.4    Newmark, H.L.5    Scalmati, A.6    Lipkin, M.7
  • 12
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • PMID: 8205551
    • Heerdt BG, Houston MA, Augenlicht LH. Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 1994; 54: 3288-3293 [PMID: 8205551]
    • (1994) Cancer Res , vol.54 , pp. 3288-3293
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 13
    • 0028859161 scopus 로고
    • Apoptosis in colorectal tumour cells: Induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate
    • PMID: 7829251
    • Hague A, Elder DJ, Hicks DJ, Paraskeva C. Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int J Cancer 1995; 60: 400-406 [PMID: 7829251 DOI: 10.1002/ijc.2910600322]
    • (1995) Int J Cancer , vol.60 , pp. 400-406
    • Hague, A.1    Elder, D.J.2    Hicks, D.J.3    Paraskeva, C.4
  • 14
    • 0030796349 scopus 로고    scopus 로고
    • Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway
    • PMID: 9288776
    • Medina V, Edmonds B, Young GP, James R, Appleton S, Zalewski PD. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res 1997; 57: 3697-3707 [PMID: 9288776]
    • (1997) Cancer Res , vol.57 , pp. 3697-3707
    • Medina, V.1    Edmonds, B.2    Young, G.P.3    James, R.4    Appleton, S.5    Zalewski, P.D.6
  • 15
    • 28644440158 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Discovery and development as anticancer agents
    • PMID: 16307490
    • Marks PA, Dokmanovic M. Histone deacetylase inhibitors: discovery and development as anticancer agents. Expert Opin Investig Drugs 2005; 14: 1497-1511 [PMID: 16307490 DOI: 10.1517/13543784.14.12.1497]
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 1497-1511
    • Marks, P.A.1    Dokmanovic, M.2
  • 16
    • 33745320974 scopus 로고    scopus 로고
    • Targeting histone deacetylase in cancer therapy
    • PMID: 16450343
    • Lin HY, Chen CS, Lin SP, Weng JR, Chen CS. Targeting histone deacetylase in cancer therapy. Med Res Rev 2006; 26: 397-413 [PMID: 16450343 DOI: 10.1002/med.20056]
    • (2006) Med Res Rev , vol.26 , pp. 397-413
    • Lin, H.Y.1    Chen, C.S.2    Lin, S.P.3    Weng, J.R.4    Chen, C.S.5
  • 17
    • 0032754225 scopus 로고    scopus 로고
    • Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin
    • PMID: 10547075
    • Bordonaro M, Mariadason JM, Aslam F, Heerdt BG, Augenlicht LH. Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin. Cell Growth Differ 1999; 10: 713-720 [PMID: 10547075]
    • (1999) Cell Growth Differ , vol.10 , pp. 713-720
    • Bordonaro, M.1    Mariadason, J.M.2    Aslam, F.3    Heerdt, B.G.4    Augenlicht, L.H.5
  • 18
    • 84926646893 scopus 로고    scopus 로고
    • p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway
    • PMID: 25697359
    • Liu C, Zhang Y, Li J, Wang Y, Ren F, Zhou Y, Wu Y, Feng Y, Zhou Y, Su F, Jia B, Wang D, Chang Z. p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway. J Biol Chem 2015; 290: 9701-9713 [PMID: 25697359 DOI: 10.1074/jbc.M114.620872]
    • (2015) J Biol Chem , vol.290 , pp. 9701-9713
    • Liu, C.1    Zhang, Y.2    Li, J.3    Wang, Y.4    Ren, F.5    Zhou, Y.6    Wu, Y.7    Feng, Y.8    Zhou, Y.9    Su, F.10    Jia, B.11    Wang, D.12    Chang, Z.13
  • 19
    • 0029811434 scopus 로고    scopus 로고
    • Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C
    • PMID: 8887544
    • Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC. Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J 1996; 15: 4526-4536 [PMID: 8887544]
    • (1996) EMBO J , vol.15 , pp. 4526-4536
    • Cook, D.1    Fry, M.J.2    Hughes, K.3    Sumathipala, R.4    Woodgett, J.R.5    Dale, T.C.6
  • 21
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • PMID: 8259519
    • Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor protein with catenins. Science 1993; 262: 1734-1737 [PMID: 8259519 DOI: 10.1126/science.8259519]
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 22
    • 0028987249 scopus 로고
    • Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • PMID: 7708772
    • Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 1995; 92: 3046-3050 [PMID: 7708772 DOI: 10.1073/pnas.92.7.3046]
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 23
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • PMID: 8757136
    • Behrens J, von Kries JP, Kühl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996; 382: 638-642 [PMID: 8757136 DOI: 10.1038/382638a0]
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kühl, M.3    Bruhn, L.4    Wedlich, D.5    Grosschedl, R.6    Birchmeier, W.7
  • 25
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
    • PMID: 9065401
    • Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 1997; 275: 1784-1787 [PMID: 9065401 DOI: 10.1126/science.275.5307.1784]
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3    Van Wichen, D.4    De Weger, R.5    Kinzler, K.W.6    Vogelstein, B.7    Clevers, H.8
  • 26
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • PMID: 9065402
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275: 1787-1790 [PMID: 9065402 DOI: 10.1126/science.275.5307.1787]
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6    Kinzler, K.W.7
  • 27
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • PMID: 11057903
    • Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000; 103: 311-320 [PMID: 11057903 DOI: 10.1016/S0092-8674(00]00122-7]
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 28
    • 0037096906 scopus 로고    scopus 로고
    • The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
    • PMID: 12045208
    • Albuquerque C, Breukel C, van der Luijt R, Fidalgo P, Lage P, Slors FJ, Leitão CN, Fodde R, Smits R. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet 2002; 11: 1549-1560 [PMID: 12045208 DOI: 10.1093/hmg/11.13.1549]
    • (2002) Hum Mol Genet , vol.11 , pp. 1549-1560
    • Albuquerque, C.1    Breukel, C.2    Van Der Luijt, R.3    Fidalgo, P.4    Lage, P.5    Slors, F.J.6    Leitão, C.N.7    Fodde, R.8    Smits, R.9
  • 29
    • 43149117058 scopus 로고    scopus 로고
    • Hyperinduction of Wnt activity: A new paradigm for the treatment of colorectal cancer?
    • PMID: 18488710
    • Bordonaro M, Lazarova DL, Sartorelli AC. Hyperinduction of Wnt activity: a new paradigm for the treatment of colorectal cancer? Oncol Res 2008; 17: 1-9 [PMID: 18488710]
    • (2008) Oncol Res , vol.17 , pp. 1-9
    • Bordonaro, M.1    Lazarova, D.L.2    Sartorelli, A.C.3
  • 31
    • 84908185262 scopus 로고    scopus 로고
    • Safely targeting cancer stem cells via selective catenin coactivator antagonism
    • PMID: 24975284
    • Lenz HJ, Kahn M. Safely targeting cancer stem cells via selective catenin coactivator antagonism. Cancer Sci 2014; 105: 1087-1092 [PMID: 24975284 DOI: 10.1111/cas.12471]
    • (2014) Cancer Sci , vol.105 , pp. 1087-1092
    • Lenz, H.J.1    Kahn, M.2
  • 32
    • 24744470274 scopus 로고    scopus 로고
    • Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation
    • PMID: 16093313
    • Teo JL, Ma H, Nguyen C, Lam C, Kahn M. Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation. Proc Natl Acad Sci USA 2005; 102: 12171-12176 [PMID: 16093313 DOI: 10.1073/pnas.0504600102]
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12171-12176
    • Teo, J.L.1    Ma, H.2    Nguyen, C.3    Lam, C.4    Kahn, M.5
  • 33
    • 19944422429 scopus 로고    scopus 로고
    • Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression
    • PMID: 15782138
    • Ma H, Nguyen C, Lee KS, Kahn M. Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression. Oncogene 2005; 24: 3619-3631 [PMID: 15782138 DOI: 10.1038/sj.onc.1208433]
    • (2005) Oncogene , vol.24 , pp. 3619-3631
    • Ma, H.1    Nguyen, C.2    Lee, K.S.3    Kahn, M.4
  • 34
    • 34248393912 scopus 로고    scopus 로고
    • Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency
    • PMID: 17372190
    • Miyabayashi T, Teo JL, Yamamoto M, McMillan M, Nguyen C, Kahn M. Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc Natl Acad Sci USA 2007; 104: 5668-5673 [PMID: 17372190 DOI: 10.1073/pnas.0701331104]
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5668-5673
    • Miyabayashi, T.1    Teo, J.L.2    Yamamoto, M.3    McMillan, M.4    Nguyen, C.5    Kahn, M.6
  • 35
    • 78649318098 scopus 로고    scopus 로고
    • The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators
    • PMID: 20920541
    • Teo JL, Kahn M. The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators. Adv Drug Deliv Rev 2010; 62: 1149-1155 [PMID: 20920541 DOI: 10.1016/j.addr.2010.09.012]
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 1149-1155
    • Teo, J.L.1    Kahn, M.2
  • 36
    • 0032189630 scopus 로고    scopus 로고
    • Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
    • PMID: 9774110
    • Waltzer L, Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature 1998; 395: 521-525 [PMID: 9774110 DOI: 10.1038/26785]
    • (1998) Nature , vol.395 , pp. 521-525
    • Waltzer, L.1    Bienz, M.2
  • 37
    • 0034678610 scopus 로고    scopus 로고
    • The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
    • PMID: 10775268
    • Hecht A, Vleminckx K, Stemmler MP, van Roy F, Kemler R. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J 2000; 19: 1839-1850 [PMID: 10775268 DOI: 10.1093/emboj/19.8.1839]
    • (2000) EMBO J , vol.19 , pp. 1839-1850
    • Hecht, A.1    Vleminckx, K.2    Stemmler, M.P.3    Van Roy, F.4    Kemler, R.5
  • 38
    • 34247615104 scopus 로고    scopus 로고
    • CBP/p300 are bimodal regulators of Wnt signaling
    • PMID: 17410209
    • Li J, Sutter C, Parker DS, Blauwkamp T, Fang M, Cadigan KM. CBP/p300 are bimodal regulators of Wnt signaling. EMBO J 2007; 26: 2284-2294 [PMID: 17410209 DOI: 10.1038/sj.emboj.7601667]
    • (2007) EMBO J , vol.26 , pp. 2284-2294
    • Li, J.1    Sutter, C.2    Parker, D.S.3    Blauwkamp, T.4    Fang, M.5    Cadigan, K.M.6
  • 39
    • 11144353713 scopus 로고    scopus 로고
    • Acetylation of beta-catenin by p300 regulates betacatenin-Tcf4 interaction
    • PMID: 15060161
    • Lévy L, Wei Y, Labalette C, Wu Y, Renard CA, Buendia MA, Neuveut C. Acetylation of beta-catenin by p300 regulates betacatenin-Tcf4 interaction. Mol Cell Biol 2004; 24: 3404-3414 [PMID: 15060161 DOI: 10.1128/MCB.24.8.3404-3414.2004]
    • (2004) Mol Cell Biol , vol.24 , pp. 3404-3414
    • Lévy, L.1    Wei, Y.2    Labalette, C.3    Wu, Y.4    Renard, C.A.5    Buendia, M.A.6    Neuveut, C.7
  • 40
    • 77953715690 scopus 로고    scopus 로고
    • Targeting Wnt signaling: Can we safely eradicate cancer stem cells?
    • PMID: 20530697
    • Takahashi-Yanaga F, Kahn M. Targeting Wnt signaling: can we safely eradicate cancer stem cells? Clin Cancer Res 2010; 16: 3153-3162 [PMID: 20530697 DOI: 10.1158/1078-0432.CCR-09-2943]
    • (2010) Clin Cancer Res , vol.16 , pp. 3153-3162
    • Takahashi-Yanaga, F.1    Kahn, M.2
  • 41
    • 84882935561 scopus 로고    scopus 로고
    • CBP activity mediates effects of the Histone deacetylase inhibitor butyrate on WNT activity and apoptosis in colon cancer cells
    • PMID: 23901348
    • Lazarova DL, Chiaro C, Wong T, Drago E, Rainey A, O'Malley S, Bordonaro M. CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells. J Cancer 2013; 4: 481-490 [PMID: 23901348 DOI: 10.7150/jca.6583]
    • (2013) J Cancer , vol.4 , pp. 481-490
    • Lazarova, D.L.1    Chiaro, C.2    Wong, T.3    Drago, E.4    Rainey, A.5    O'Malley, S.6    Bordonaro, M.7
  • 42
    • 84882968975 scopus 로고    scopus 로고
    • p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells
    • PMID: 23901349
    • Lazarova DL, Wong T, Chiaro C, Drago E, Bordonaro M. p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells. J Cancer 2013; 4: 491-501 [PMID: 23901349 DOI: 10.7150/jca.6582]
    • (2013) J Cancer , vol.4 , pp. 491-501
    • Lazarova, D.L.1    Wong, T.2    Chiaro, C.3    Drago, E.4    Bordonaro, M.5
  • 43
    • 84896934913 scopus 로고    scopus 로고
    • Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells
    • PMID: 24563675
    • Lazarova D, Lee A, Wong T, Marian B, Chiaro C, Rainey C, Bordonaro M. Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells. J Cancer 2014; 5: 203-213 [PMID: 24563675 DOI: 10.7150/jca.8569]
    • (2014) J Cancer , vol.5 , pp. 203-213
    • Lazarova, D.1    Lee, A.2    Wong, T.3    Marian, B.4    Chiaro, C.5    Rainey, C.6    Bordonaro, M.7
  • 44
    • 84922138512 scopus 로고    scopus 로고
    • Canonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent manner
    • PMID: 25635944
    • Grigson ER, Ozerova M, Pisklakova A, Liu H, Sullivan DM, Nefedova Y. Canonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent manner. PLoS One 2015; 10: e0117693 [PMID: 25635944 DOI: 10.1371/journal.pone.0117693]
    • (2015) PLoS One , vol.10
    • Grigson, E.R.1    Ozerova, M.2    Pisklakova, A.3    Liu, H.4    Sullivan, D.M.5    Nefedova, Y.6
  • 45
    • 33847740988 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in cancer stemness and malignant behavior
    • PMID: 17306971
    • Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 2007; 19: 150-158 [PMID: 17306971 DOI: 10.1016/j.ceb.2007.02.007]
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 150-158
    • Fodde, R.1    Brabletz, T.2
  • 46
    • 84886777635 scopus 로고    scopus 로고
    • Prognostic impact of p300 expression in patients with colorectal cancer
    • PMID: 24142575
    • Huh JW, Kim HC, Kim SH, Park YA, Cho YB, Yun SH, Lee WY, Chun HK. Prognostic impact of p300 expression in patients with colorectal cancer. J Surg Oncol 2013; 108: 374-377 [PMID: 24142575 DOI: 10.1002/jso.23405]
    • (2013) J Surg Oncol , vol.108 , pp. 374-377
    • Huh, J.W.1    Kim, H.C.2    Kim, S.H.3    Park, Y.A.4    Cho, Y.B.5    Yun, S.H.6    Lee, W.Y.7    Chun, H.K.8
  • 47
    • 84901705019 scopus 로고    scopus 로고
    • Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP
    • PMID: 24748645
    • Jia Y, Nie F, Du A, Chen Z, Qin Y, Huang T, Song X, Li L. Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP. J Mol Cell Biol 2014; 6: 231-239 [PMID: 24748645 DOI: 10.1093/jmcb/mju014]
    • (2014) J Mol Cell Biol , vol.6 , pp. 231-239
    • Jia, Y.1    Nie, F.2    Du, A.3    Chen, Z.4    Qin, Y.5    Huang, T.6    Song, X.7    Li, L.8
  • 48
    • 84907466558 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells
    • PMID: 25050608
    • Götze S, Coersmeyer M, Müller O, Sievers S. Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells. Int J Oncol 2014; 45: 1715-1723 [PMID: 25050608 DOI: 10.3892/ijo.2014.25]
    • (2014) Int J Oncol , vol.45 , pp. 1715-1723
    • Götze, S.1    Coersmeyer, M.2    Müller, O.3    Sievers, S.4
  • 49
    • 84868371289 scopus 로고    scopus 로고
    • Tcf3 and cell cycle factors contribute to butyrate resistance in colorectal cancer cells
    • PMID: 23063976
    • Chiaro C, Lazarova DL, Bordonaro M. Tcf3 and cell cycle factors contribute to butyrate resistance in colorectal cancer cells. Biochem Biophys Res Commun 2012; 428: 121-126 [PMID: 23063976 DOI: 10.1016/j.bbrc.2012.10.018]
    • (2012) Biochem Biophys Res Commun , vol.428 , pp. 121-126
    • Chiaro, C.1    Lazarova, D.L.2    Bordonaro, M.3
  • 50
    • 84901285520 scopus 로고    scopus 로고
    • Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription
    • PMID: 24720539
    • Kida A, Kahn M. Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription. Curr Mol Pharmacol 2013; 6: 204-210 [PMID: 24720539]
    • (2013) Curr Mol Pharmacol , vol.6 , pp. 204-210
    • Kida, A.1    Kahn, M.2
  • 51
    • 84884132973 scopus 로고    scopus 로고
    • Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen
    • PMID: 24012757
    • Hao J, Ao A, Zhou L, Murphy CK, Frist AY, Keel JJ, Thorne CA, Kim K, Lee E, Hong CC. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Rep 2013; 4: 898-904 [PMID: 24012757 DOI: 10.1016/j.celrep.2013.07.047]
    • (2013) Cell Rep , vol.4 , pp. 898-904
    • Hao, J.1    Ao, A.2    Zhou, L.3    Murphy, C.K.4    Frist, A.Y.5    Keel, J.J.6    Thorne, C.A.7    Kim, K.8    Lee, E.9    Hong, C.C.10
  • 52
    • 80555146643 scopus 로고    scopus 로고
    • A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells
    • PMID: 22073312
    • Bordonaro M, Tewari S, Cicco CE, Atamna W, Lazarova DL. A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells. PLoS One 2011; 6: e27308 [PMID: 22073312 DOI: 10.1371/journal.pone.0027308]
    • (2011) PLoS One , vol.6
    • Bordonaro, M.1    Tewari, S.2    Cicco, C.E.3    Atamna, W.4    Lazarova, D.L.5
  • 53
    • 84883006588 scopus 로고    scopus 로고
    • Extreme fluctuations in Wnt/betacatenin signaling as an approach for colon cancer prevention and therapy
    • Lazarova DL, Bordonaro M. Extreme fluctuations in Wnt/betacatenin signaling as an approach for colon cancer prevention and therapy. Adv Stud Biol 2012; 4: 351-362
    • (2012) Adv Stud Biol , vol.4 , pp. 351-362
    • Lazarova, D.L.1    Bordonaro, M.2
  • 54
    • 0842320994 scopus 로고    scopus 로고
    • A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability
    • PMID: 14732695
    • Ionov Y, Matsui S, Cowell JK. A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability. Proc Natl Acad Sci USA 2004; 101: 1273-1278 [PMID: 14732695 DOI: 10.10173/pnas.0307276101]
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1273-1278
    • Ionov, Y.1    Matsui, S.2    Cowell, J.K.3
  • 55
    • 84945437544 scopus 로고    scopus 로고
    • Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors
    • Epub ahead of print ,PMID: 25213383
    • Woerner SM, Tosti E, Yuan YP, Kloor M, Bork P, Edelmann W, Gebert J. Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors. Mol Carcinog 2014; Epub ahead of print [PMID: 25213383 DOI: 10.1002/mc.22213]
    • (2014) Mol Carcinog
    • Woerner, S.M.1    Tosti, E.2    Yuan, Y.P.3    Kloor, M.4    Bork, P.5    Edelmann, W.6    Gebert, J.7
  • 56
    • 84921275022 scopus 로고    scopus 로고
    • The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth
    • PMID: 25082960
    • Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Mol Cancer Ther 2014; 13: 2303-2314 [PMID: 25082960 DOI: 10.1158/1535-7163.MCT-13-1005]
    • (2014) Mol Cancer Ther , vol.13 , pp. 2303-2314
    • Arensman, M.D.1    Telesca, D.2    Lay, A.R.3    Kershaw, K.M.4    Wu, N.5    Donahue, T.R.6    Dawson, D.W.7
  • 57
    • 84938069305 scopus 로고    scopus 로고
    • Inhibition of β-catenin/p300 interaction proximalizes mouse embryonic lung epithelium
    • PMID: 25505699
    • Sasaki T, Kahn M. Inhibition of β-catenin/p300 interaction proximalizes mouse embryonic lung epithelium. Transl Respir Med 2014; 2: 8 [PMID: 25505699 DOI: 10.1186/s40247-014-0008]
    • (2014) Transl Respir Med , vol.2 , pp. 8
    • Sasaki, T.1    Kahn, M.2


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