-
1
-
-
84871990888
-
Emergence and global spread of epidemic healthcare-associated Clostridium difficile
-
He, M. et al. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat. Genet. 45, 109-113 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 109-113
-
-
He, M.1
-
2
-
-
55249105923
-
Clostridium difficile-more difficult than ever
-
Kelly, C. P. & LaMont, J. T. Clostridium difficile-more difficult than ever. New Engl. J. Med. 359, 1932-1940 (2008).
-
(2008)
New Engl. J. Med.
, vol.359
, pp. 1932-1940
-
-
Kelly, C.P.1
LaMont, J.T.2
-
3
-
-
35048865459
-
Prospective study of Clostridium difficile-associated disease in Europe with phenotypic and genotypic characterization of the isolates
-
Barbut, F. et al. Prospective study of Clostridium difficile-associated disease in Europe with phenotypic and genotypic characterization of the isolates. Clin. Microbiol. Infect. 13, 1048-1057 (2007).
-
(2007)
Clin. Microbiol. Infect.
, vol.13
, pp. 1048-1057
-
-
Barbut, F.1
-
4
-
-
62249088494
-
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe
-
Kuijper, E. J. et al. Update of Clostridium difficile infection due to PCR ribotype 027 in Europe. Eurosurveil. 13, e18942 (2008).
-
(2008)
Eurosurveil.
, vol.13
-
-
Kuijper, E.J.1
-
5
-
-
77954581650
-
The Changing Epidemiology of Clostridium difficile Infections
-
Freeman, J. et al. The Changing Epidemiology of Clostridium difficile Infections. Clin. Microbiol. Rev. 23, 529-549 (2010).
-
(2010)
Clin. Microbiol. Rev.
, vol.23
, pp. 529-549
-
-
Freeman, J.1
-
6
-
-
0019503053
-
Epidemiology of antibiotic-associated colitis: Isolation of Clostridium difficile from the hospital environment
-
Fekety, R. et al. Epidemiology of antibiotic-associated colitis: isolation of Clostridium difficile from the hospital environment. Am. J. Med. 70, 906-908 (1981).
-
(1981)
Am. J. Med.
, vol.70
, pp. 906-908
-
-
Fekety, R.1
-
7
-
-
39749111479
-
Measures to Control and Prevent Clostridium difficile Infection
-
Gerding, D. N., Muto, C. A. & Owens, R. C. Measures to Control and Prevent Clostridium difficile Infection. Clin. Infect. Dis. 46, S43-S49 (2008).
-
(2008)
Clin. Infect. Dis.
, vol.46
, pp. S43-S49
-
-
Gerding, D.N.1
Muto, C.A.2
Owens, R.C.3
-
8
-
-
77957376775
-
Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production
-
Merrigan, M. et al. Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production. J. Bacteriol. 192, 4904-4911 (2010).
-
(2010)
J. Bacteriol.
, vol.192
, pp. 4904-4911
-
-
Merrigan, M.1
-
9
-
-
84869222966
-
Association of Relapse of Clostridium difficile Disease with BI/NAP1/027
-
Marsh, J. W. et al. Association of Relapse of Clostridium difficile Disease with BI/NAP1/027. J. Clin. Microbiol. 50, 4078-4082 (2012).
-
(2012)
J. Clin. Microbiol.
, vol.50
, pp. 4078-4082
-
-
Marsh, J.W.1
-
10
-
-
80052859469
-
Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027
-
Burns, D. A., Heeg, D., Cartman, S. T. & Minton, N. P. Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027. PLoS ONE 6, e24894 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Burns, D.A.1
Heeg, D.2
Cartman, S.T.3
Minton, N.P.4
-
11
-
-
84903612457
-
Clostridium difficile spore biology: Sporulation, germination, and spore structural proteins
-
Paredes-Sabja, D., Shen, A. & Sorg, J. A. Clostridium difficile spore biology: sporulation, germination, and spore structural proteins. Trends Microbiol. 22, 406-16 (2014).
-
(2014)
Trends Microbiol.
, vol.22
, pp. 406-416
-
-
Paredes-Sabja, D.1
Shen, A.2
Sorg, J.A.3
-
12
-
-
41549142775
-
Bile salts and glycine as co-germinants for Clostridium difficile spores
-
Sorg, J. A. & Sonenshein, A. L. Bile salts and glycine as co-germinants for Clostridium difficile spores. J. Bacteriol. 190, 2505-2512 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 2505-2512
-
-
Sorg, J.A.1
Sonenshein, A.L.2
-
13
-
-
17444366186
-
Clostridium difficile toxins: Mechanism of action and role in disease
-
Voth, D. & Ballard, J. Clostridium difficile toxins: mechanism of action and role in disease. Clin. Microbiol. Rev. 18, 247-263 (2005).
-
(2005)
Clin. Microbiol. Rev.
, vol.18
, pp. 247-263
-
-
Voth, D.1
Ballard, J.2
-
14
-
-
4444382260
-
Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: A changing pattern of disease severity
-
Pépin, J. et al. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. Canad. Med. Assoc. J. 171, 466-472 (2004).
-
(2004)
Canad. Med. Assoc. J.
, vol.171
, pp. 466-472
-
-
Pépin, J.1
-
15
-
-
33846156548
-
A portrait of the geographic dissemination of the clostridium difficile north American pulsed-field type 1 strain and the epidemiology of C. Difficile-associated disease in québec
-
Hubert, B. et al. A Portrait of the Geographic Dissemination of the Clostridium difficile North American Pulsed-Field Type 1 Strain and the Epidemiology of C. difficile-Associated Disease in Québec. Clin. Infect. Dis. 44, 238-244 (2007).
-
(2007)
Clin. Infect. Dis.
, vol.44
, pp. 238-244
-
-
Hubert, B.1
-
16
-
-
25144469664
-
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
-
Warny, M. et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. The Lancet 366, 1079-1084 (2005).
-
(2005)
The Lancet
, vol.366
, pp. 1079-1084
-
-
Warny, M.1
-
17
-
-
79955752437
-
Comparison of toxin and spore production in clinically relevant strains of Clostridium difficile
-
Vohra, P. & Poxton, I. Comparison of toxin and spore production in clinically relevant strains of Clostridium difficile. Microbiol. 157, 1343-1353 (2011).
-
(2011)
Microbiol.
, vol.157
, pp. 1343-1353
-
-
Vohra, P.1
Poxton, I.2
-
18
-
-
77958132074
-
Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile
-
Lanis, J., Barua, S. & Ballard, J. Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Path. 6, e1001061 (2010).
-
(2010)
PLoS Path.
, vol.6
-
-
Lanis, J.1
Barua, S.2
Ballard, J.3
-
19
-
-
46349087809
-
Clinical Severity of Clostridium difficile PCR Ribotype 027: A Case-Case Study
-
Morgan, O. W. et al. Clinical Severity of Clostridium difficile PCR Ribotype 027: A Case-Case Study. PLoS ONE 3, e1812 (2008).
-
(2008)
PLoS ONE
, vol.3
, pp. e1812
-
-
Morgan, O.W.1
-
20
-
-
82455209353
-
Lack of Association between Clinical Outcome of Clostridium difficile Infections, Strain Type, and Virulence-Associated Phenotypes
-
Sirard, S., Valiquette, L. & Fortier, L.-C. Lack of Association between Clinical Outcome of Clostridium difficile Infections, Strain Type, and Virulence-Associated Phenotypes. J. Clin. Microbiol. 49, 4040-4046 (2011).
-
(2011)
J. Clin. Microbiol.
, vol.49
, pp. 4040-4046
-
-
Sirard, S.1
Valiquette, L.2
Fortier, L.-C.3
-
21
-
-
84903191942
-
Epidemic Clostridium difficile strains demonstrate increased competitive fitness over non-epidemic isolates
-
Robinson, C. D., Auchtung, J. M., Collins, J. & Britton, R. Epidemic Clostridium difficile strains demonstrate increased competitive fitness over non-epidemic isolates. Infect. Immun. 82, 2815-25 (2014).
-
(2014)
Infect. Immun.
, vol.82
, pp. 2815-2825
-
-
Robinson, C.D.1
Auchtung, J.M.2
Collins, J.3
Britton, R.4
-
22
-
-
0035436310
-
Mathematical modeling of Clostridium difficile infection
-
Starr, J. M. & Campbell, A. Mathematical modeling of Clostridium difficile infection. Clin. Microbiol. Infect. 7, 432-437 (2001).
-
(2001)
Clin. Microbiol. Infect.
, vol.7
, pp. 432-437
-
-
Starr, J.M.1
Campbell, A.2
-
23
-
-
57149141496
-
Spatio-temporal stochastic modelling of Clostridium difficile
-
Starr, J. M., Campbell, A., Renshaw, E., Poxton, I. R. & Gibson, G. J. Spatio-temporal stochastic modelling of Clostridium difficile. J. Hosp. Infect. 71, 49-56 (2009).
-
(2009)
J. Hosp. Infect.
, vol.71
, pp. 49-56
-
-
Starr, J.M.1
Campbell, A.2
Renshaw, E.3
Poxton, I.R.4
Gibson, G.J.5
-
24
-
-
84894370790
-
A simulation-based assessment of strategies to control clostridium difficile transmission and infection
-
Rubin, M. A. et al. A Simulation-Based Assessment of Strategies to Control Clostridium Difficile Transmission and Infection. PLoS ONE 8, e80671 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Rubin, M.A.1
-
25
-
-
84921345769
-
An Agent-based Simulation Model for Clostridium difficile Infection Control
-
Codella, J., Safdar, N., Heffernan, R. & Alagoz, O. An Agent-based Simulation Model for Clostridium difficile Infection Control. Med. Dec. Making 35, 211-29 (2015).
-
(2015)
Med. Dec. Making
, vol.35
, pp. 211-229
-
-
Codella, J.1
Safdar, N.2
Heffernan, R.3
Alagoz, O.4
-
26
-
-
84904406665
-
Effectiveness of screening hospital admissions to detect asymptomatic carriers of Clostridium difficile: A modeling evaluation
-
Lanzas, C. & Dubberke, D. Effectiveness of screening hospital admissions to detect asymptomatic carriers of Clostridium difficile: a modeling evaluation. Infect. Control Hosp. Epidemiol. 35, 1043-1050 (2014).
-
(2014)
Infect. Control Hosp. Epidemiol.
, vol.35
, pp. 1043-1050
-
-
Lanzas, C.1
Dubberke, D.2
-
27
-
-
79957940848
-
Epidemiological Model for Clostridium difficile Transmission in Healthcare Settings
-
Lanzas, C., Dubberke, E. Lu, Z., Reske, K. & Gröhn, Y. Epidemiological Model for Clostridium difficile Transmission in Healthcare Settings. Infect. Control Hosp. Epidemiol. 32, 553-561 (2011).
-
(2011)
Infect. Control Hosp. Epidemiol.
, vol.32
, pp. 553-561
-
-
Lanzas, C.1
Dubberke Lu E, Z.2
Reske, K.3
Gröhn, Y.4
-
28
-
-
84881529136
-
Clostridium difficile exposure as an insidious source of infection in healthcare settings: An epidemiological model
-
Yakob, L., Riley, T., Paterson, D. & Clements, A. Clostridium difficile exposure as an insidious source of infection in healthcare settings: an epidemiological model. BMC Infect. Dis. 13, 376 (2013).
-
(2013)
BMC Infect. Dis.
, vol.13
, pp. 376
-
-
Yakob, L.1
Riley, T.2
Paterson, D.3
Clements, A.4
-
29
-
-
84901976695
-
Assessing control bundles for Clostridium difficile: A review and mathematical model
-
Yakob, L., Riley, T. V., Paterson, D. L., Marquess, J. & Clements, A. C. A. Assessing control bundles for Clostridium difficile: a review and mathematical model. Emerg Microbes Infect 3, e43; doi: 10.1038/emi.2014.43 (2014).
-
(2014)
Emerg Microbes Infect
, vol.3
, pp. e43
-
-
Yakob, L.1
Riley, T.V.2
Paterson, D.L.3
Marquess, J.4
Clements, A.C.A.5
-
30
-
-
84857741366
-
Characterisation of Clostridium difficile Hospital Ward-Based Transmission Using Extensive Epidemiological Data and Molecular Typing
-
Walker, A. S. et al. Characterisation of Clostridium difficile Hospital Ward-Based Transmission Using Extensive Epidemiological Data and Molecular Typing. PLoS Med 9, e1001172 (2012).
-
(2012)
PLoS Med
, vol.9
-
-
Walker, A.S.1
-
31
-
-
84884510020
-
Diverse sources of C. Difficile Infection identified on whole-genome sequencing
-
Eyre, D. W. et al. Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing. New Engl. J. Med. 369, 1195-1205 (2013).
-
(2013)
New Engl. J. Med.
, vol.369
, pp. 1195-1205
-
-
Eyre, D.W.1
-
32
-
-
48749126211
-
Different ribotypes in community-acquired Clostridium difficile
-
Bignardi, G. E. & Settle, C. Different ribotypes in community-acquired Clostridium difficile. J. Hosp. Infect. 70, 96-98 (2008).
-
(2008)
J. Hosp. Infect.
, vol.70
, pp. 96-98
-
-
Bignardi, G.E.1
Settle, C.2
-
33
-
-
0000998185
-
A contribution to the mathematical theory of epidemics
-
Kermack, W. O. & McKendrick, A. G. A Contribution to the Mathematical Theory of Epidemics. Proc. Roy. Soc. A 115, 700-721 (1927).
-
(1927)
Proc. Roy. Soc. A
, vol.115
, pp. 700-721
-
-
Kermack, W.O.1
McKendrick, A.G.2
-
34
-
-
33745120517
-
Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from Eastern and Western Canada
-
MacCannell, D. et al. Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from Eastern and Western Canada. J. Clin. Microbiol. 44, 2147-2152 (2006).
-
(2006)
J. Clin. Microbiol.
, vol.44
, pp. 2147-2152
-
-
MacCannell, D.1
-
35
-
-
84866675037
-
Changing Epidemiology of Clostridium difficile Infection Following the Introduction of a National Ribotyping-Based Surveillance Scheme in England
-
Wilcox, M. H. et al. Changing Epidemiology of Clostridium difficile Infection Following the Introduction of a National Ribotyping-Based Surveillance Scheme in England. Clin. Infect. Dis. 55, 1056-1063 (2012).
-
(2012)
Clin. Infect. Dis.
, vol.55
, pp. 1056-1063
-
-
Wilcox, M.H.1
-
36
-
-
78650825355
-
Clostridium difficile infection in Europe: A hospital-based survey
-
Bauer, M. P. et al. Clostridium difficile infection in Europe: a hospital-based survey. The Lancet 377, 63-73 (2011).
-
(2011)
The Lancet
, vol.377
, pp. 63-73
-
-
Bauer, M.P.1
-
37
-
-
65449155189
-
Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain
-
O'Connor, J. R., Johnson, S. & Gerding, D. N. Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain. Gastroenterol. 136, 1913-1924 (2009).
-
(2009)
Gastroenterol.
, vol.136
, pp. 1913-1924
-
-
O'Connor, J.R.1
Johnson, S.2
Gerding, D.N.3
-
38
-
-
84893506501
-
Parameters for the Mathematical Modelling of Clostridium difficile Acquisition and Transmission: A Systematic Review
-
Otete, E. H. et al. Parameters for the Mathematical Modelling of Clostridium difficile Acquisition and Transmission: A Systematic Review. PLoS ONE 8, e84224 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Otete, E.H.1
-
40
-
-
80455173556
-
Host and Pathogen Factors for Clostridium difficile Infection and Colonization
-
Loo, V. G. et al. Host and Pathogen Factors for Clostridium difficile Infection and Colonization. New Engl. J. Med. 365, 1693-1703 (2011).
-
(2011)
New Engl. J. Med.
, vol.365
, pp. 1693-1703
-
-
Loo, V.G.1
-
41
-
-
61549089404
-
Effects of treatment with antimicrobial agents on the human colonic microflora
-
Rafii, F., Sutherland, J. B. & Cerniglia, C. E. Effects of treatment with antimicrobial agents on the human colonic microflora. Therap. Clin. Risk Manag. 4, 1343-1358 (2008).
-
(2008)
Therap. Clin. Risk Manag.
, vol.4
, pp. 1343-1358
-
-
Rafii, F.1
Sutherland, J.B.2
Cerniglia, C.E.3
-
42
-
-
0021397229
-
Treatment of antibiotic-associated pseudomembranous colitis
-
Bartlett, J. G. Treatment of antibiotic-associated pseudomembranous colitis. Rev. Infect. Dis. 6, S235-S241 (1984).
-
(1984)
Rev. Infect. Dis.
, vol.6
, pp. S235-S241
-
-
Bartlett, J.G.1
-
44
-
-
38049084783
-
Update on the changing epidemiology of Clostridium difficile-associated disease
-
McFarland, L. V. Update on the changing epidemiology of Clostridium difficile-associated disease. Nat. Clin. Pract. Gastroenterol. Hepatol. 5, 40-48 (2008).
-
(2008)
Nat. Clin. Pract. Gastroenterol. Hepatol.
, vol.5
, pp. 40-48
-
-
McFarland, L.V.1
-
45
-
-
65449165706
-
Treatment of Clostridium difficile-Associated Disease
-
Leffler, D. A. & Lamont, J. T. Treatment of Clostridium difficile-Associated Disease. Gastroenterol. 136, 1899-1912 (2009).
-
(2009)
Gastroenterol.
, vol.136
, pp. 1899-1912
-
-
Leffler, D.A.1
LaMont, J.T.2
|