Selenocysteine oxidation in glutathione peroxidase catalysis: An MS-supported quantum mechanics study

Free Radical Biology and Medicine

Volumn 87, Issue , 2015, Pages 1-14

  Orian, Laura ^a   Mauri, Pierluigi ^b   Roveri, Antonella ^a   Toppo, Stefano ^a   Benazzi, Louise ^b   Bosello Travain, Valentina ^a   De Palma, Antonella ^b   Maiorino, Matilde ^a   Miotto, Giovanni ^a   Zaccarin, Mattia ^a   Polimeno, Antonino ^a   Flohé, Leopold ^a   Ursini, Fulvio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

Author keywords

DFT calculation; Glutathione peroxidases; MS MS analysisofcatalyticintermediates; Selenenylamideformation; Selenium catalysis

Indexed keywords

AMIDE; ARGININE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; NITROGEN; OXYGEN; PEROXIREDOXIN; PROTEIN TYROSINE PHOSPHATASE 1B; SELENIUM; SELENOCYSTEINE; SELENOPROTEIN P; SULFUR; THIOREDOXIN; WATER; HYDROGEN PEROXIDE;

ANIMAL CELL; ARTICLE; BOVINE; CALCULATION; CATALYSIS; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; ENZYME SUBSTRATE; LIQUID CHROMATOGRAPHY; MALE; MOLECULAR WEIGHT; NONHUMAN; NUCLEOPHILICITY; OXIDATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; QUANTUM MECHANICS; RAT; SITE DIRECTED MUTAGENESIS; SURFACE PROPERTY; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; QUANTUM THEORY;

RATTUS;

ANIMALS; CATALYSIS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; KINETICS; OXIDATION-REDUCTION; QUANTUM THEORY; RATS; SELENIUM; SELENOCYSTEINE; SULFUR; TANDEM MASS SPECTROMETRY;

EID: 84938087516     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.06.011     Document Type: Article

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