Influence of phospholipid types and animal models on the accelerated blood clearance phenomenon of PEGylated liposomes upon repeated injection

Drug Delivery

Volumn 22, Issue 5, 2015, Pages 598-607

  Xu, Huan ^a   Ye, Feifei ^a   Hu, Meina ^a   Yin, Pengpeng ^a   Zhang, Wei ^a   Li, Yan ^a   Yu, Xiu ^a   Deng, Yihui ^b  

^a LIAONING NORMAL UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Accelerated blood clearance phenomenon; Animal models; Liposome; Phospholipid types; Polyethylene glycol

Indexed keywords

DIPALMITOYLPHOSPHATIDYLCHOLINE; EGG PHOSPHATIDYLCHOLINE; EGG SPHINGOMYELIN; HYDROGENATED SOY PHOSPHATIDYLCHOLINE; IMMUNOGLOBULIN M ANTIBODY; LIPOSOME; MACROGOL; PHOSPHOLIPID DERIVATIVE; SOYBEAN PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG; ANTIBODY; IMMUNOGLOBULIN M; MACROGOL DERIVATIVE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; SPHINGOMYELIN;

ACCELERATED BLOOD CLEARANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CIRCULATION TIME; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; GUINEA PIG MODEL; LIPOSOMAL DELIVERY; LIVER; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PHOSPHOLIPID MEMBRANE; PLASMA CLEARANCE; PRIORITY JOURNAL; RABBIT MODEL; RAT; REPEATED DRUG DOSE; SPLEEN; TISSUE DISTRIBUTION; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL MODEL; GUINEA PIG; IMMUNOLOGY; METABOLIC CLEARANCE RATE; METABOLISM; OVUM; RABBIT; SOYBEAN;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ANIMALS; ANTIBODIES; GUINEA PIGS; IMMUNOGLOBULIN M; LIPOSOMES; LIVER; METABOLIC CLEARANCE RATE; MICE; MODELS, ANIMAL; OVUM; PHOSPHATIDYLCHOLINES; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; RABBITS; RATS; SOYBEANS; SPHINGOMYELINS;

EID: 84937879935     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2014.885998     Document Type: Article

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