Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice

Journal of Controlled Release

Volumn 95, Issue 3, 2004, Pages 403-412

  Ishida, Tatsuhiro ^a   Ichikawa, Takako ^a   Ichihara, Masako ^a   Sadzuka, Yasuyuki ^b   Kiwada, Hiroshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

3H cholesterylhexadecyl ether; 3H CHE; Accelerated blood clearance; CHOL; Cholesterol; Dipalmitoyl phosphatidylcholine; Dipalmitoyl phosphatidylglycerol; DPPC; DPPG; HEPC; Liposomes; Polyethylene glycol (PEG); Repeated injection

Indexed keywords

BLOOD; DRUG THERAPY; LIPIDS; PHARMACOKINETICS; POLYETHYLENE GLYCOLS;

LIPOSOMES; PHYSIOCHEMICAL PROPERTIES;

LIVING SYSTEMS STUDIES;

1,2 DISTEAROYLGLYCERO 3 PHOSPHOETHANOLAMINE[METHOXY(POLYETHYLENEGLYCOL) 2000]; 1,2 DISTEAROYLGLYCERO 3 PHOSPHOETHANOLAMINE[METHOXY(POLYETHYLENEGLYCOL) 5000]; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLGLYCEROL; LIPOSOME; MACROGOL; MACROGOL 2000; OCTADECYLAMINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG COATING; DRUG DISTRIBUTION; DRUG FORMULATION; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; MALE; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PLASMA CLEARANCE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SURFACE CHARGE; SURFACE PROPERTY;

ANIMALS; CHEMISTRY, PHYSICAL; DRUG ADMINISTRATION SCHEDULE; INJECTIONS, INTRAVENOUS; JAPAN; LIPOSOMES; LIVER; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; POLYETHYLENE GLYCOLS; RADIOPHARMACEUTICALS; TIME FACTORS;

EID: 1542614051     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2003.12.011     Document Type: Article

References (44)

1. Allen T.M., Hansen C.B. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim. Biophys. Acta. 1068:1991;133-141.
2. Allen T.M. Long-circulating (sterically stabilized) liposomes for targeted drug delivery. Trends Pharmacol. Sci. 15:1994;215-220.
3. Ishida T., Maeda R., Ichihara M., Irimura K., Kiwada H. Accelerated clearance of PEGylated liposomes in rat after repeated injection. J. Control. Release. 88:2003;35-42.
4. Ishida T., Masuda K., Ichikawa T., Ichihara M., Irimura K., Kiwada H. Accelerated clearance of a second injection of PEGylated liposomes in mice. Int. J. Pharm. 255:2003;167-174.
5. Dams E.T.M., Laverman P., Oyen W.J.G., Storm G., Scherphof G.L., Van der Meer J.W.M., Corstens F.H.M., Boerman O.C. Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes. J. Pharmacol. Exp. Ther. 292:2000;1071-1079.
6. Laverman P., Carstens M.G., Boerman O.C., Dams E.T.M., Oyen W.J.G., Rooijen N.V., Corstens F.H.M., Storm G. Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection. J. Pharmacol. Exp. Ther. 298:2001;607-612.
7. Goins B., Phillips W.T., Klippers R. Repeat injection studies of technetium-99m-labeled PEG-liposomes in the same animal. J. Liposome Res. 8:1998;265-281.
8. Oussoren C., Storm G. Effect of repeated intravenous administration on the circulation kinetics of poly(ethyleneglycol)-liposomes in rats. J. Liposome Res. 9:1999;349-355.
9. Vanetten E.W.M., Ottelambillion M., Vanvianen W., Tenkate M.T., Bakkerwoudenberg I.A.J.M. Biodistribution of liposomal amphotericin B (ambisome) and amphotericin B desoxycholate (fungizone) in uninfected immunocompetent mice and leucopenic mice infected with Candida albicans. J. Antimicrob. Chemother. 35:1995;509-519.
10. Vanetten E.W.M., Vanvianen W., Tijhuis R.H.G., Storm G., Bakkerwoudenberg I.A.J.M. Sterically stabilized amphotericin B liposomes: toxicity and biodistribution in mice. J. Control. Release. 37:1995;123-129.
11. Allen T.M. Liposome targeting in animal models: problems and opportunities. J. Liposome Res. 7:1997;315-329.
12. Senior J.H. Fate and behaviour of liposomes in vivo: a review of controlling factors. Crit. Rev. Ther. Drug Carr. Syst. 3:1987;123-193.
13. Allen T.M., Hansen C.B., Lopes de Menezes D.E. Pharmacokinetics of long circulating liposomes. Adv. Drug Deliv. Rev. 16:1995;267-284.
14. Senior J., Gregoriadis G. Stability of small unilamellar liposomes in serum and clearance from the circulation. Life Sci. 30:1982;2123-2136.
15. Senior J.H. Fate and behavior of liposomes in vivo: a review of controlling factors. Crit. Rev. Ther. Drug Carr. Syst. 3:1987;123-193.
16. Papahadjopoulos D., Allen T.M., Gabizon A., Mayhew E., Matthay K., Huang S.K., Lee K.D., Woodle M.C., Lasic D.D., Redemann C., Martin F.J. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. U. S. A. 88:1991;11460-11464.
17. Klibanov A.L., Maruyama K., Beckerleg A.M., Torchilin V.P., Huang L. Activity of amphipathic poly(ethyleneglycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target. Biochim. Biophys. Acta. 1062:1991;142-148.
18. Lopes de Menezes D.E., Pilarski L.M., Allen T.M. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 58:1998;3320-3330.
19. Bartlett G.R. Phosphorus assay in column chromatography. J. Biol. Chem. 234:1959;466-468.
20. Allen T.M. Lopez-Berestein G., Fidler I. Liposomes in the Therapy of Infectious Disease and Cancer. UCLA Symposium in Molecular and Cellular Biology. vol. 3:1984;205-224 CRC Press, Boca Raton, FL.
21. Harashima H., Yamane C., Kume Y., Kiwada H. Kinetic analysis of AUC-dependent saturable clearance of liposomes: mathematical description of AUC dependency. Eur. J. Pharm. Biopharm. 21:1993;299-308.
22. Allen T.M. Liposomal drug formulations. Rationale for development and what we can expect for the future. Drugs. 56:1998;747-756.
23. Sharpe M., Easthope S.E., Keating G.M., Lamb H.M. Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS-related Kaposi's sarcoma. Drugs. 62:2002;2089-2126.
24. Minodier P., Petornaz K., Horelt A., Gernier J.M. Liposomal amphotericin B in the treatment of visceral leishmaniasis immunocompetent patients. Fundam. Clin. Pharmacol. 17:2003;183-188.
25. Dupont B. Overview of the lipid formulations of amphotericin B. J. Antimicrob. Chemother. 49:2002;31-36.
26. Batist G., Barton J., Chaikin P., Swenson C., Welles L. Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy. Expert Opin. Pharmacother. 2002:2003;1739-1751.
27. Goebel F.D., Goldstein D., Goos M., Jablonowski H., Stewart J.S. Efficacy and safety of stealth liposomal doxorubicin in AIDS-related Kaposi's sarcoma. Br. J. Cancer. 73:1996;989-994.
28. Halm U., Etzrodt G., Schiefke I., Schmidt F., Witzigmann H., Mossner J., Berr F. A phase II study of PEGylated liposomal doxorubicin for treatment of advanced hepatocellular carcinoma. Ann. Oncol. 11:2000;113-114.
29. Harrison M., Tomlinson D., Stewart S. Liposomal-entrapped doxorubicin: an active agent in AIDS-related Kaposi's sarcoma. J. Clin. Oncol. 13:1995;914-920.
30. Hubert A., Lyass O., Pode D., Gabison A. Doxil (Caelyx): an exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer. Anticancer Drugs. 11:2000;123-127.
31. Kenworthy A.K., Hristova K., Needham D., Mcintosh T.J. Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol). Biophys. J. 68:1995;1921-1936.
32. Needham D., McIntosh T.J., Lasic D.D. Repulsive interactions and mechanical stability of polymer-grafted lipid membranes. Biochim. Biophys. Acta. 1108:1992;40-48.
33. Woodle M., Lasic D.D. Sterically stabilized liposomes. Biochim. Biophys. Acta. 1113:1992;171-199.
34. Nikolova A.N., Jones M.N. Effect of grafted PEG-2000 on the size and permeability of vesicles. Biochim. Biophys. Acta. 1304:1996;120-128.
35. Nicholas A.R., Scott M.J., Kennedy N.I., Jones M.N. Effect of grafted polyethylene glycol (PEG) on the size, encapsulation efficiency and permeability of vesicles. Biochim. Biophys. Acta. 1463:2000;167-178.
36. Du H., Chandaroy P., Hui S.W. Grafted poly-(ethylene glycol) on lipid surfaces inhibits protein adsorption and cell adhesion. Biochim. Biophys. Acta. 1326:1997;236-248.
37. Lasic D.D., Woodle M.C., Papahadjopoulos D. On the molecular mechanism of steric stabilization of liposomes in biological fluids. J. Liposome Res. 2:1992;335-353.
38. Moghimi S.M., Patel H.M. Serum mediated recognition of liposomes by phagocytic cells of the reticuloendotherial system: the concept of tissue specificity. Adv. Drug Deliv. Rev. 32:1998;45-60.
39. Ishida T., Harashima H., Kiwada H. Liposome clearance. Biosci. Rep. 22:2002;197-224.
40. Devine D.V., Marjan J.M. The role of immunoproteins in the survival of liposomes in the circulation. Crit. Rev. Ther. Drug Carr. Syst. 14:1997;105-131.
41. Moghimi S.M., Patel H.M. Modulation of murine liver macrophage clearance of liposomes by diethylstilbestrol. The effect of vesicle surface charge and a role for the complement receptor Mac-1 (CD11b/CD18) of newly recruited macrophages in liposome recognition. J. Control. Release. 78:2002;55-65.
42. Daemen T., Hofstede G., Ten Kate M.T., Bakker-Woudenberg I.A., Scherphof G.L. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages. Int. J. Cancer. 61:1995;716-721.
43. Daemen T., Hofstede G., Ten Kate M.T., Bakker-Eoundenberg I.A., Scherphof G.L. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages. Int. J. Cancer. 61:1995;666-671.
44. Gordon A.N., Granai C.O., Rose P.G., Hainsworth J., Lopez A., Weissman C., Rosales R., Sharpington T. Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer. J. Clin. Oncol. 18:2000;3093-3100.