Nano-sized water-in-oil-in-water emulsion enhances intestinal absorption of calcein, a high solubility and low permeability compound

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 223-232

  Koga, Kenjiro ^a   Takarada, Nobuo ^a   Takada, Kanji ^b  

^a HOKURIKU UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

BCS class III; Emulsifier; Intestinal absorption; Nanoparticle; w o w emulsion

Indexed keywords

CALCEIN; ESTER DERIVATIVE; GELUCIRE; POLYVINYL ALCOHOL; RICINOLEIC ACID TETRAGLYCERIN ESTER; SOYBEAN OIL; STEARIC ACID HEXAGLYCERIN ESTER; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL MEMBRANE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; INTESTINE ABSORPTION; MALE; NANOEMULSION; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; EMULSIFYING AGENTS; EMULSIONS; FLUORESCEINS; INTESTINAL ABSORPTION; JEJUNUM; MALE; NANOPARTICLES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 75449099531     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.09.004     Document Type: Article

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