Repeated injections of PEGylated liposomal topotecan induces accelerated blood clearance phenomenon in rats

European Journal of Pharmaceutical Sciences

Volumn 45, Issue 5, 2012, Pages 539-545

  Ma, Yanling ^a   Yang, Qiang ^a   Wang, Long ^a   Zhou, Xinyu ^a   Zhao, Yongxue ^a   Deng, Yihui ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Accelerate blood clearance (ABC) phenomenon; PEGylated liposomes; Polyethylene glycol (PEG); Topotecan

Indexed keywords

MACROGOL; TOPOTECAN;

ACCELERATED BLOOD CLEARANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG LIVER LEVEL; DRUG SPLEEN LEVEL; DRUG TISSUE LEVEL; MALE; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; RAT;

ANIMALS; DOXORUBICIN; IMMUNOGLOBULIN M; LIPOSOMES; MALE; METABOLIC CLEARANCE RATE; MITOXANTRONE; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; TOPOTECAN;

EID: 84862780803     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.11.014     Document Type: Article

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