Inhibition of recombinant human mitochondrial and cytosolic aldehyde dehydrogenases by two candidates for the active metabolites of disulfiram

Biochemistry

Volumn 36, Issue 44, 1997, Pages 13748-13754

  Lam, Jennifer P ^a   Mays, Dennis C ^a   Lipsky, James J ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; DISULFIRAM; DRUG METABOLITE; ESTERASE; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; RECOMBINANT PROTEIN; S METHYL N,N DIETHYLTHIOCARBAMATE SULFONE; S METHYL N,N DIETHYLTHIOCARBAMATE SULFOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOSOL; DRUG METABOLISM; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL;

ALDEHYDE DEHYDROGENASE; ANIMALS; CATALYSIS; CYTOSOL; DISULFIRAM; DITIOCARB; HUMANS; ISOENZYMES; MITOCHONDRIA, LIVER; RATS; RECOMBINANT PROTEINS; SULFONES;

EID: 0030828669     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970948e     Document Type: Article

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