-
1
-
-
70349274478
-
Adverse effects associated with persistent stimulation of Leydig cells with hCG in vitro
-
Aggarwal A., Misro M.M., Maheshwari A., Sehgal N., Nandan D. Adverse effects associated with persistent stimulation of Leydig cells with hCG in vitro. Mol. Reprod. Dev 2009, 76:1076-1083.
-
(2009)
Mol. Reprod. Dev
, vol.76
, pp. 1076-1083
-
-
Aggarwal, A.1
Misro, M.M.2
Maheshwari, A.3
Sehgal, N.4
Nandan, D.5
-
2
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:7915-7922.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
3
-
-
10344243498
-
Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study
-
Araujo A.B., O'Donnell A.B., Brambilla D.J., Simpson W.B., Longcope C., Matsumoto A.M., et al. Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study. J. Clin. Endocrinol. Metab 2004, 89:5920-5926.
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, pp. 5920-5926
-
-
Araujo, A.B.1
O'Donnell, A.B.2
Brambilla, D.J.3
Simpson, W.B.4
Longcope, C.5
Matsumoto, A.M.6
-
4
-
-
0029125737
-
Alteration of the adrenal antioxidant defense system during aging in rats
-
Azhar S., Cao L., Reaven E. Alteration of the adrenal antioxidant defense system during aging in rats. J. Clin. Invest 1995, 96:1414-1424.
-
(1995)
J. Clin. Invest
, vol.96
, pp. 1414-1424
-
-
Azhar, S.1
Cao, L.2
Reaven, E.3
-
5
-
-
84877013644
-
Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells
-
Beattie M.C., Chen H., Fan J., Papadopoulos V., Miller P., Zirkin B.R. Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells. Biol. Reprod 2013, 88:101-107.
-
(2013)
Biol. Reprod
, vol.88
, pp. 101-107
-
-
Beattie, M.C.1
Chen, H.2
Fan, J.3
Papadopoulos, V.4
Miller, P.5
Zirkin, B.R.6
-
6
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev 1998, 78:547-581.
-
(1998)
Physiol. Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
7
-
-
1542329063
-
Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells
-
Cao L., Leers-Sucheta S., Azhar S. Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells. J. Steroid Biochem. Mol. Biol 2004, 88:61-67.
-
(2004)
J. Steroid Biochem. Mol. Biol
, vol.88
, pp. 61-67
-
-
Cao, L.1
Leers-Sucheta, S.2
Azhar, S.3
-
8
-
-
0033592972
-
Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging
-
Chen H., Zirkin B.R. Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:14877-14881.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 14877-14881
-
-
Chen, H.1
Zirkin, B.R.2
-
9
-
-
0028558510
-
Age-related decreased Leydig cell testosterone production in the brown Norway rat
-
Chen H., Hardy M.P., Huhtaniemi I., Zirkin B.R. Age-related decreased Leydig cell testosterone production in the brown Norway rat. J. Androl 1994, 15:551-557.
-
(1994)
J. Androl
, vol.15
, pp. 551-557
-
-
Chen, H.1
Hardy, M.P.2
Huhtaniemi, I.3
Zirkin, B.R.4
-
10
-
-
0034899370
-
Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: relationship to reduced steroidogenic function?
-
Chen H., Cangello D., Benson S., Folmer J., Zhu H., Trush M.A., et al. Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: relationship to reduced steroidogenic function?. Exp. Gerontol 2001, 36:1361-1373.
-
(2001)
Exp. Gerontol
, vol.36
, pp. 1361-1373
-
-
Chen, H.1
Cangello, D.2
Benson, S.3
Folmer, J.4
Zhu, H.5
Trush, M.A.6
-
11
-
-
0036227563
-
Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro
-
Chen H., Hardy M.P., Zirkin B.R. Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro. Endocrinology 2002, 143:1637-1642.
-
(2002)
Endocrinology
, vol.143
, pp. 1637-1642
-
-
Chen, H.1
Hardy, M.P.2
Zirkin, B.R.3
-
12
-
-
4644300593
-
Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells
-
Chen H., Liu J., Luo L., Zirkin B.R. Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells. Endocrinology 2004, 145:4441-4446.
-
(2004)
Endocrinology
, vol.145
, pp. 4441-4446
-
-
Chen, H.1
Liu, J.2
Luo, L.3
Zirkin, B.R.4
-
13
-
-
24644476532
-
Vitamin E, aging and Leydig cell steroidogenesis
-
Chen H., Liu J., Luo L., Baig M.U., Kim J.M., Zirkin B.R. Vitamin E, aging and Leydig cell steroidogenesis. Exp. Gerontol 2005, 40:728-736.
-
(2005)
Exp. Gerontol
, vol.40
, pp. 728-736
-
-
Chen, H.1
Liu, J.2
Luo, L.3
Baig, M.U.4
Kim, J.M.5
Zirkin, B.R.6
-
14
-
-
42449098527
-
Effect of glutathione depletion on Leydig cell steroidogenesis in young and old brown Norway rats
-
Chen H., Pechenino A.S., Liu J., Beattie M.C., Brown T.R., Zirkin B.R. Effect of glutathione depletion on Leydig cell steroidogenesis in young and old brown Norway rats. Endocrinology 2008, 149:2612-2619.
-
(2008)
Endocrinology
, vol.149
, pp. 2612-2619
-
-
Chen, H.1
Pechenino, A.S.2
Liu, J.3
Beattie, M.C.4
Brown, T.R.5
Zirkin, B.R.6
-
15
-
-
77952958235
-
Effect of glutathione redox state on Leydig cell susceptibility to acute oxidative stress
-
Chen H., Zhou L., Lin C.Y., Beattie M.C., Liu J., Zirkin B.R. Effect of glutathione redox state on Leydig cell susceptibility to acute oxidative stress. Mol. Cell. Endocrinol 2010, 323:147-154.
-
(2010)
Mol. Cell. Endocrinol
, vol.323
, pp. 147-154
-
-
Chen, H.1
Zhou, L.2
Lin, C.Y.3
Beattie, M.C.4
Liu, J.5
Zirkin, B.R.6
-
16
-
-
11444261268
-
Gene expression profiling of NRF2-mediated protection against oxidative injury
-
Cho H.Y., Reddy S.P., Debiase A., Yamamoto M., Kleeberger S.R. Gene expression profiling of NRF2-mediated protection against oxidative injury. Free Radic. Biol. Med 2005, 38:325-343.
-
(2005)
Free Radic. Biol. Med
, vol.38
, pp. 325-343
-
-
Cho, H.Y.1
Reddy, S.P.2
Debiase, A.3
Yamamoto, M.4
Kleeberger, S.R.5
-
18
-
-
0036220150
-
Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells
-
Culty M., Luo L., Yao Z.X., Chen H., Papadopoulos V., Zirkin B.R. Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells. J. Androl 2002, 23:439-447.
-
(2002)
J. Androl
, vol.23
, pp. 439-447
-
-
Culty, M.1
Luo, L.2
Yao, Z.X.3
Chen, H.4
Papadopoulos, V.5
Zirkin, B.R.6
-
19
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
20
-
-
0023637369
-
Steroid synthesis-dependent, oxygen-mediated damage of mitochondrial and microsomal cytochrome P-450 enzymes in rat Leydig cell cultures
-
Georgiou M., Perkins L.M., Payne A.H. Steroid synthesis-dependent, oxygen-mediated damage of mitochondrial and microsomal cytochrome P-450 enzymes in rat Leydig cell cultures. Endocrinology 1987, 121:1390-1399.
-
(1987)
Endocrinology
, vol.121
, pp. 1390-1399
-
-
Georgiou, M.1
Perkins, L.M.2
Payne, A.H.3
-
21
-
-
33644501791
-
Activation of the Nrf2-ARE signaling pathway: a promising strategy in cancer prevention
-
Giudice A., Montella M. Activation of the Nrf2-ARE signaling pathway: a promising strategy in cancer prevention. Bioessays 2006, 28:169-181.
-
(2006)
Bioessays
, vol.28
, pp. 169-181
-
-
Giudice, A.1
Montella, M.2
-
22
-
-
33646701679
-
Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells
-
Hanukoglu I. Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells. Drug Metab. Rev 2006, 38:171-196.
-
(2006)
Drug Metab. Rev
, vol.38
, pp. 171-196
-
-
Hanukoglu, I.1
-
23
-
-
0035097033
-
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
-
Baltimore Longitudinal Study of Aging
-
Harman S.M., Metter E.J., Tobin J.D., Pearson J., Blackman M.R. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J. Clin. Endocrinol. Metab 2001, 86:724-731. Baltimore Longitudinal Study of Aging.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 724-731
-
-
Harman, S.M.1
Metter, E.J.2
Tobin, J.D.3
Pearson, J.4
Blackman, M.R.5
-
24
-
-
15544383555
-
The chemistry behind antioxidant capacity assays
-
Huang D., Ou B., Prior R.L. The chemistry behind antioxidant capacity assays. J. Agric. Food Chem 2005, 53:1841-1856.
-
(2005)
J. Agric. Food Chem
, vol.53
, pp. 1841-1856
-
-
Huang, D.1
Ou, B.2
Prior, R.L.3
-
25
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun 1997, 236:313-322.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
-
26
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
Itoh K., Tong K.I., Yamamoto M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic. Biol. Med 2004, 36:1208-1213.
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
27
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
Itoh K., Tong K.I., Yamamoto M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic. Biol. Med 2004, 36:1208-1213.
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
28
-
-
33748052967
-
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
-
Kobayashi M., Yamamoto M. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv. Enzyme Regul 2006, 46:113-140.
-
(2006)
Adv. Enzyme Regul
, vol.46
, pp. 113-140
-
-
Kobayashi, M.1
Yamamoto, M.2
-
29
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak M.K., Wakabayashi N., Itoh K., Motohashi H., Yamamoto M., Kensler T.W. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem 2003, 278:8135-8145.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
30
-
-
33644857861
-
Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice
-
Lacombe A., Lelievre V., Roselli C.E., Salameh W., Lue Y.H., Lawson G., et al. Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:3793-3798.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 3793-3798
-
-
Lacombe, A.1
Lelievre, V.2
Roselli, C.E.3
Salameh, W.4
Lue, Y.H.5
Lawson, G.6
-
31
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
-
Lee J.M., Calkins M.J., Chan K., Kan Y.W., Johnson J.A. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem 2003, 278:12029-12038.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 12029-12038
-
-
Lee, J.M.1
Calkins, M.J.2
Chan, K.3
Kan, Y.W.4
Johnson, J.A.5
-
32
-
-
0033105616
-
Down-regulation of steroidogenic acute regulatory (StAR) protein in rat Leydig cells: implications for regulation of testosterone production during aging
-
Leers-Sucheta S., Stocco D.M., Azhar S. Down-regulation of steroidogenic acute regulatory (StAR) protein in rat Leydig cells: implications for regulation of testosterone production during aging. Mech. Ageing Dev 1999, 107:197-203.
-
(1999)
Mech. Ageing Dev
, vol.107
, pp. 197-203
-
-
Leers-Sucheta, S.1
Stocco, D.M.2
Azhar, S.3
-
33
-
-
59849113546
-
Molecular mechanisms of Nrf2-mediated antioxidant response
-
Li W., Kong A.N. Molecular mechanisms of Nrf2-mediated antioxidant response. Mol. Carcinog 2009, 48:91-104.
-
(2009)
Mol. Carcinog
, vol.48
, pp. 91-104
-
-
Li, W.1
Kong, A.N.2
-
34
-
-
0027275205
-
Age-related decline in the steroidogenic capacity of isolated rat Leydig cells: a defect in cholesterol mobilization and processing
-
Liao C., Reaven E., Azhar S. Age-related decline in the steroidogenic capacity of isolated rat Leydig cells: a defect in cholesterol mobilization and processing. J. Steroid Biochem. Mol. Biol 1993, 46:39-47.
-
(1993)
J. Steroid Biochem. Mol. Biol
, vol.46
, pp. 39-47
-
-
Liao, C.1
Reaven, E.2
Azhar, S.3
-
35
-
-
23944463647
-
Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men
-
Liu P.Y., Takahashi P.Y., Roebuck P.D., Iranmanesh A., Veldhuis J.D. Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men. Am. J. Physiol. Regul. Integr. Comp. Physiol 2005, 289:R721-R728.
-
(2005)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.289
, pp. R721-R728
-
-
Liu, P.Y.1
Takahashi, P.Y.2
Roebuck, P.D.3
Iranmanesh, A.4
Veldhuis, J.D.5
-
36
-
-
0029827114
-
Are Leydig cell steroidogenic enzymes differentially regulated with aging?
-
Luo L., Chen H., Zirkin B.R. Are Leydig cell steroidogenic enzymes differentially regulated with aging?. J. Androl 1996, 17:509-515.
-
(1996)
J. Androl
, vol.17
, pp. 509-515
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
37
-
-
0035189247
-
Leydig cell aging: steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme
-
Luo L., Chen H., Zirkin B.R. Leydig cell aging: steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme. J. Androl 2001, 22:149-156.
-
(2001)
J. Androl
, vol.22
, pp. 149-156
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
38
-
-
10844285662
-
Temporal relationships among testosterone production, steroidogenic acute regulatory protein (StAR), and P450 side-chain cleavage enzyme (P450scc) during Leydig cell aging
-
Luo L., Chen H., Zirkin B.R. Temporal relationships among testosterone production, steroidogenic acute regulatory protein (StAR), and P450 side-chain cleavage enzyme (P450scc) during Leydig cell aging. J. Androl 2005, 26:25-31.
-
(2005)
J. Androl
, vol.26
, pp. 25-31
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
39
-
-
33644534186
-
Aging and the brown Norway rat leydig cell antioxidant defense system
-
Luo L., Chen H., Trush M.A., Show M.D., Anway M.D., Zirkin B.R. Aging and the brown Norway rat leydig cell antioxidant defense system. J. Androl 2006, 27:240-247.
-
(2006)
J. Androl
, vol.27
, pp. 240-247
-
-
Luo, L.1
Chen, H.2
Trush, M.A.3
Show, M.D.4
Anway, M.D.5
Zirkin, B.R.6
-
40
-
-
84884530635
-
Steroid hormone synthesis in mitochondria
-
Miller W.L. Steroid hormone synthesis in mitochondria. Mol. Cell. Endocrinol 2013, 379:62-73.
-
(2013)
Mol. Cell. Endocrinol
, vol.379
, pp. 62-73
-
-
Miller, W.L.1
-
41
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
42
-
-
77957233987
-
Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner
-
Nakamura B.N., Lawson G., Chan J.Y., Banuelos J., Cortes M.M., Hoang Y.D., et al. Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner. Free Radic. Biol. Med 2010, 49:1368-1379.
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 1368-1379
-
-
Nakamura, B.N.1
Lawson, G.2
Chan, J.Y.3
Banuelos, J.4
Cortes, M.M.5
Hoang, Y.D.6
-
43
-
-
47849083585
-
Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults
-
Osburn W.O., Kensler T.W. Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults. Mutat. Res 2008, 659:31-39.
-
(2008)
Mutat. Res
, vol.659
, pp. 31-39
-
-
Osburn, W.O.1
Kensler, T.W.2
-
44
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher P., Beckman J.S., Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev 2007, 87:315-424.
-
(2007)
Physiol. Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
45
-
-
0030024408
-
Induction of lipid peroxidation during steroidogenesis in the rat testis
-
Peltola V., Huhtaniemi I., Metsa-Ketela T., Ahotupa M. Induction of lipid peroxidation during steroidogenesis in the rat testis. Endocrinology 1996, 137:105-112.
-
(1996)
Endocrinology
, vol.137
, pp. 105-112
-
-
Peltola, V.1
Huhtaniemi, I.2
Metsa-Ketela, T.3
Ahotupa, M.4
-
46
-
-
0021361841
-
Oxygen-mediated damage of microsomal cytochrome P-450 enzymes in cultured leydig cells. Role in steroidogenic desensitization
-
Quinn P.G., Payne A.H. Oxygen-mediated damage of microsomal cytochrome P-450 enzymes in cultured leydig cells. Role in steroidogenic desensitization. J. Biol. Chem 1984, 259:4130-4135.
-
(1984)
J. Biol. Chem
, vol.259
, pp. 4130-4135
-
-
Quinn, P.G.1
Payne, A.H.2
-
47
-
-
0023038023
-
High affinity binding of substrate and effector ligands to testicular microsomal cytochrome P-450
-
Quinn P.G., Payne A.H. High affinity binding of substrate and effector ligands to testicular microsomal cytochrome P-450. J. Steroid Biochem 1986, 25:943-949.
-
(1986)
J. Steroid Biochem
, vol.25
, pp. 943-949
-
-
Quinn, P.G.1
Payne, A.H.2
-
48
-
-
0034306267
-
Mitochondria, oxygen free radicals, disease and ageing
-
Raha S., Robinson B.H. Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem. Sci 2000, 25:502-508.
-
(2000)
Trends Biochem. Sci
, vol.25
, pp. 502-508
-
-
Raha, S.1
Robinson, B.H.2
-
49
-
-
51249104026
-
Pro-oxidant shift in glutathione redox state during aging
-
Rebrin I., Sohal R.S. Pro-oxidant shift in glutathione redox state during aging. Adv. Drug Deliv. Rev 2008, 60:1545-1552.
-
(2008)
Adv. Drug Deliv. Rev
, vol.60
, pp. 1545-1552
-
-
Rebrin, I.1
Sohal, R.S.2
-
50
-
-
0034941860
-
Purification of rat leydig cells: increased yields after unit-gravity sedimentation of collagenase-dispersed interstitial cells
-
Salva A., Klinefelter G.R., Hardy M.P. Purification of rat leydig cells: increased yields after unit-gravity sedimentation of collagenase-dispersed interstitial cells. J. Androl 2001, 22:665-671.
-
(2001)
J. Androl
, vol.22
, pp. 665-671
-
-
Salva, A.1
Klinefelter, G.R.2
Hardy, M.P.3
-
51
-
-
0035039021
-
Protein oxidation in aging and age-related diseases
-
Stadtman E.R. Protein oxidation in aging and age-related diseases. Ann. N. Y. Acad. Sci 2001, 928:22-38.
-
(2001)
Ann. N. Y. Acad. Sci
, vol.928
, pp. 22-38
-
-
Stadtman, E.R.1
-
52
-
-
34547673497
-
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
-
Szabo C., Ischiropoulos H., Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov 2007, 6:662-680.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 662-680
-
-
Szabo, C.1
Ischiropoulos, H.2
Radi, R.3
-
53
-
-
34548722316
-
Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men
-
Takahashi P.Y., Votruba P., Abu-Rub M., Mielke K., Veldhuis J.D. Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men. J. Clin. Endocrinol. Metab 2007, 92:3626-3632.
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 3626-3632
-
-
Takahashi, P.Y.1
Votruba, P.2
Abu-Rub, M.3
Mielke, K.4
Veldhuis, J.D.5
-
54
-
-
83455242982
-
Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men
-
Veldhuis J.D., Liu P.Y., Keenan D.M., Takahashi P.Y. Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men. Am. J. Physiol. Endocrinol. Metab 2012, 302:E117-E122.
-
(2012)
Am. J. Physiol. Endocrinol. Metab
, vol.302
, pp. E117-E122
-
-
Veldhuis, J.D.1
Liu, P.Y.2
Keenan, D.M.3
Takahashi, P.Y.4
-
55
-
-
33845442925
-
Mechanistic studies of the Nrf2-Keap1 signaling pathway
-
Zhang D.D. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab. Rev 2006, 38:769-789.
-
(2006)
Drug Metab. Rev
, vol.38
, pp. 769-789
-
-
Zhang, D.D.1
-
56
-
-
84883728576
-
Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells
-
Zhou L., Beattie M.C., Lin C.Y., Liu J., Traore K., Papadopoulos V., et al. Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells. Reprod. Toxicol 2013, 42:95-101.
-
(2013)
Reprod. Toxicol
, vol.42
, pp. 95-101
-
-
Zhou, L.1
Beattie, M.C.2
Lin, C.Y.3
Liu, J.4
Traore, K.5
Papadopoulos, V.6
-
57
-
-
0033796721
-
Regulation of Leydig cell steroidogenic function during aging
-
Zirkin B.R., Chen H. Regulation of Leydig cell steroidogenic function during aging. Biol. Reprod 2000, 63:977-981.
-
(2000)
Biol. Reprod
, vol.63
, pp. 977-981
-
-
Zirkin, B.R.1
Chen, H.2
|