-
1
-
-
3643130143
-
A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotrophin-releasing hormone antagonist ganirelix (Org 37462) to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant follicle stimulating hormone (Puregon)
-
The ganirelix dose-finding study group
-
The Ganivelix Dose-Finding Study Group. A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotrophin-releasing hormone antagonist ganirelix (Org 37462) to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant follicle stimulating hormone (Puregon). The ganirelix dose-finding study group. Hum Reprod 13: 3023-3031, 1998.
-
(1998)
Hum Reprod
, vol.13
, pp. 3023-3031
-
-
-
2
-
-
0031594725
-
Aging results in attenuated gonadotropin releasing hormone-luteinizing hormone axis responsiveness to glutamate receptor agonist N-methyl-D-aspartate
-
Bonavera JJ, SwerdlolT RS, Sinha Hakim AP, Lue YH, and Wang C. Aging results in attenuated gonadotropin releasing hormone-luteinizing hormone axis responsiveness to glutamate receptor agonist N-methyl-D-aspartate. J Neuroendocrinol 10: 93-99, 1998.
-
(1998)
J Neuroendocrinol
, vol.10
, pp. 93-99
-
-
Bonavera, J.J.1
Swerdlolt, R.S.2
Sinha Hakim, A.P.3
Lue, Y.H.4
Wang, C.5
-
3
-
-
0021274804
-
Age-related difference in the effect of castration upon hypothalamic LHRH content in male rat
-
Bourguignon JP, Gerard A, and Franchimont P. Age-related difference in the effect of castration upon hypothalamic LHRH content in male rat. Neuroendocrinology. 38: 376-381, 1984.
-
(1984)
Neuroendocrinology
, vol.38
, pp. 376-381
-
-
Bourguignon, J.P.1
Gerard, A.2
Franchimont, P.3
-
4
-
-
0029828126
-
In vivo bioactivities and clearance patterns of highly purified luteinizing hormone isoforms
-
Burgon PG, Stanton PG, and Robertson DM. In vivo bioactivities and clearance patterns of highly purified luteinizing hormone isoforms. Endocrinology 137: 4827-4836, 1996.
-
(1996)
Endocrinology
, vol.137
, pp. 4827-4836
-
-
Burgon, P.G.1
Stanton, P.G.2
Robertson, D.M.3
-
5
-
-
0033592972
-
Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging
-
Chen H and Zirkin BR. Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging. Proc Natl Acad Sci USA 96: 14877-14881, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14877-14881
-
-
Chen, H.1
Zirkin, B.R.2
-
6
-
-
33645477736
-
Testicular function and neuroendocrine activity in senescent mice
-
Chubb CE and Desjardins C. Testicular function and neuroendocrine activity in senescent mice. Am J Physiol Endocrinol Metab 247: E410-E415, 1984.
-
(1984)
Am J Physiol Endocrinol Metab
, vol.247
-
-
Chubb, C.E.1
Desjardins, C.2
-
7
-
-
0015388725
-
Kinetics of [3H]-testosterone metabolism in normal young men: Effects of medroxyprogesterone acetate (provera) administration
-
Clark AF, Calandra KS, and Bird CK. Kinetics of [3H]-testosterone metabolism in normal young men: effects of medroxyprogesterone acetate (provera) administration. J Steroid Biochem 3: 837-842, 1972.
-
(1972)
J Steroid Biochem
, vol.3
, pp. 837-842
-
-
Clark, A.F.1
Calandra, K.S.2
Bird, C.K.3
-
8
-
-
0019452776
-
Autoregulation of testosterone secretion in perfused rat testes
-
Darney, KJ Jr and Ewing L. Autoregulation of testosterone secretion in perfused rat testes. Endocrinology 109: 993-995, 1981.
-
(1981)
Endocrinology
, vol.109
, pp. 993-995
-
-
Darney Jr., K.J.1
Ewing, L.2
-
9
-
-
0023188313
-
Sustained inhibitory actions of a potent antagonist of gonadotropin-releasing hormone in postmenopausal women
-
Davis MR, Veldhuis JD, Rogol AD, Dufau ML, and Catt KJ. Sustained inhibitory actions of a potent antagonist of gonadotropin-releasing hormone in postmenopausal women. J Clin Endocrinol Metab 64: 1268-1274, 1987.
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 1268-1274
-
-
Davis, M.R.1
Veldhuis, J.D.2
Rogol, A.D.3
Dufau, M.L.4
Catt, K.J.5
-
10
-
-
0009606688
-
Secretion of testosterone in anesthetized dogs
-
Eik-Nes KB. Secretion of testosterone in anesthetized dogs. Endocrinology 71: 101-106, 1962.
-
(1962)
Endocrinology
, vol.71
, pp. 101-106
-
-
Eik-Nes, K.B.1
-
11
-
-
0036170745
-
Age trends in the level of serum testosterone and other hormones in middle-aged men: Longitudinal results from the Massachusetts male aging study
-
Feldman HA, Longcope C, Derby CA, Johannes CB, Araujo AB, Coviello AD, Bremner WJ, and McKinlay JB. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab 87: 589-598, 2002.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 589-598
-
-
Feldman, H.A.1
Longcope, C.2
Derby, C.A.3
Johannes, C.B.4
Araujo, A.B.5
Coviello, A.D.6
Bremner, W.J.7
McKinlay, J.B.8
-
12
-
-
0030921610
-
Specific linkages among luteinizing hormone, follicle stimulating hormone, and testosterone release in the peripheral blood and human spermatic vein: Evidence for both positive (feed-forward) and negative (feedback) within-axis regulation
-
Foresta C, Bordon P, Rossato M, Mioni R, and Veldhuis JD. Specific linkages among luteinizing hormone, follicle stimulating hormone, and testosterone release in the peripheral blood and human spermatic vein: evidence for both positive (feed-forward) and negative (feedback) within-axis regulation. J Clin Endocrinol Metab 82: 3040-3046, 1997.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3040-3046
-
-
Foresta, C.1
Bordon, P.2
Rossato, M.3
Mioni, R.4
Veldhuis, J.D.5
-
13
-
-
0028194849
-
The Brown Norway rat as a model of male reproductive aging: Evidence for both primary and secondary testicular failure
-
Gruenewald DA, Naai MA, Hess DL, and Matsumoto AM. The Brown Norway rat as a model of male reproductive aging: evidence for both primary and secondary testicular failure. J Gerontol R Psychol Sci Soc Sci 49: B42-B50, 1994.
-
(1994)
J Gerontol R Psychol Sci Soc Sci
, vol.49
-
-
Gruenewald, D.A.1
Naai, M.A.2
Hess, D.L.3
Matsumoto, A.M.4
-
14
-
-
0031736458
-
Does age-associated reduced Leydig cell testosterone production in Brown Norway rats result from under-stimulation by luteinizing hormone?
-
Grzywacz FW, Chen H, Allegretti J, and Zirkin BR. Does age-associated reduced Leydig cell testosterone production in Brown Norway rats result from under-stimulation by luteinizing hormone? J Androl 19: 625-630, 1998.
-
(1998)
J Androl
, vol.19
, pp. 625-630
-
-
Grzywacz, F.W.1
Chen, H.2
Allegretti, J.3
Zirkin, B.R.4
-
15
-
-
0035097033
-
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
-
Harman SM, Metter FJ, Tobin JD, Pearson J, and Blackman MR. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 86: 724-731, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 724-731
-
-
Harman, S.M.1
Metter, F.J.2
Tobin, J.D.3
Pearson, J.4
Blackman, M.R.5
-
16
-
-
0018950079
-
Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin
-
Harman SM and Tsitouras PD. Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin. J Clin Endocrinol Metab 51: 35-40, 1980.
-
(1980)
J Clin Endocrinol Metab
, vol.51
, pp. 35-40
-
-
Harman, S.M.1
Tsitouras, P.D.2
-
17
-
-
0000799546
-
Testosterone production and metabolic clearance rules with volumes of distribution in normal adult men and women
-
Horton R, Shinsnko J, and Forsham PH. Testosterone production and metabolic clearance rules with volumes of distribution in normal adult men and women. Acta Endocrinol 48: 446-458, 1965.
-
(1965)
Acta Endocrinol
, vol.48
, pp. 446-458
-
-
Horton, R.1
Shinsnko, J.2
Forsham, P.H.3
-
18
-
-
0022541149
-
Effects of aging on the in vitro release of gonadotropin-releasing hormone
-
Jarjour LT, Handelsman DJ, and Swerdloff RS. Effects of aging on the in vitro release of gonadotropin-releasing hormone. Endocrinology 119: 1113-1117, 1986.
-
(1986)
Endocrinology
, vol.119
, pp. 1113-1117
-
-
Jarjour, L.T.1
Handelsman, D.J.2
Swerdloff, R.S.3
-
19
-
-
0020731767
-
Diminished luteinizing hormone pulse frequency and amplitude with aging in the male rat
-
Karpas AE, Bremner WJ, Clifton DK, Steiner RA, and Dorsa DM. Diminished luteinizing hormone pulse frequency and amplitude with aging in the male rat. Endocrinology 112: 788-791, 1983.
-
(1983)
Endocrinology
, vol.112
, pp. 788-791
-
-
Karpas, A.E.1
Bremner, W.J.2
Clifton, D.K.3
Steiner, R.A.4
Dorsa, D.M.5
-
20
-
-
2342509139
-
Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements in interglandular signaling
-
Keenan DM, Alexander SL, Irvine CHG, Clarke IJ, Canny BJ, Scott CJ, Tilbrook AJ, Turner AI, and Veldhuis JD. Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements in interglandular signaling. Proc Natl Acad Sci USA 101: 6740-6745, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6740-6745
-
-
Keenan, D.M.1
Alexander, S.L.2
Irvine, C.H.G.3
Clarke, I.J.4
Canny, B.J.5
Scott, C.J.6
Tilbrook, A.J.7
Turner, A.I.8
Veldhuis, J.D.9
-
21
-
-
0030759141
-
Stochastic model of admixed basal and pulsatile hormone secretion as modulated by a deterministic oscillator
-
Keenan DM and Veldhuis JD. Stochastic model of admixed basal and pulsatile hormone secretion as modulated by a deterministic oscillator. Am J Physiol Regul Integr Comp Physiol 273: R1182-R1192, 1997.
-
(1997)
Am J Physiol Regul Integr Comp Physiol
, vol.273
-
-
Keenan, D.M.1
Veldhuis, J.D.2
-
22
-
-
0031876840
-
A biomathematical model of time-delayed feedback in the human male hypothalamic-pituitary-Leydig cell axis
-
Keenan DM and Veldhuis JD. A biomathematical model of time-delayed feedback in the human male hypothalamic-pituitary-Leydig cell axis. Am J Physiol Endocrinol Metab 275: E157-E176, 1998.
-
(1998)
Am J Physiol Endocrinol Metab
, vol.275
-
-
Keenan, D.M.1
Veldhuis, J.D.2
-
23
-
-
0035665125
-
Disruption of the hypothalamic luteinizing-hormone pulsing mechanism in aging men
-
Keenan DM and Veldhuis JD. Disruption of the hypothalamic luteinizing-hormone pulsing mechanism in aging men. Am J Physiol Regul Integr Comp Physiol 281: R1917-R1924, 2001.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.281
-
-
Keenan, D.M.1
Veldhuis, J.D.2
-
24
-
-
0034968016
-
Hypothesis testing of the aging male gonadal axis via a biomathematical construct
-
Keenan DM and Veldhuis JD. Hypothesis testing of the aging male gonadal axis via a biomathematical construct. Am J Physiol Regul Integr Comp Physiol 280: R1755-R1771, 2001.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.280
-
-
Keenan, D.M.1
Veldhuis, J.D.2
-
25
-
-
0942298219
-
Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men
-
Keenan DM and Veldhuis JD. Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men. Am J Physiol Regul Integr Comp Physiol 286: R381-R389, 2004.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.286
-
-
Keenan, D.M.1
Veldhuis, J.D.2
-
26
-
-
0026702302
-
Abrogation by a potent GnRH antagonist of the estrogen/progesterone- stimulated surge-like release of LH and FSH in postmenopausal women
-
Kolp LA, Pavlou SN, Urban RJ, Rivier JC, Vale WW, and Veldhuis JD. Abrogation by a potent GnRH antagonist of the estrogen/progesterone-stimulated surge-like release of LH and FSH in postmenopausal women. J Clin Endocrinol Metab 75: 993-997, 1992.
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 993-997
-
-
Kolp, L.A.1
Pavlou, S.N.2
Urban, R.J.3
Rivier, J.C.4
Vale, W.W.5
Veldhuis, J.D.6
-
28
-
-
0036828155
-
Anatomical and functional evidence for a neural hypothalamic-testicular pathway that is independent of the pituitary
-
Lee S, Miselis R, and Rivier C. Anatomical and functional evidence for a neural hypothalamic-testicular pathway that is independent of the pituitary. Endocrinology 143: 4447-4454, 2002.
-
(2002)
Endocrinology
, vol.143
, pp. 4447-4454
-
-
Lee, S.1
Miselis, R.2
Rivier, C.3
-
29
-
-
16544393215
-
The rationale, efficacy and safety of androgen therapy in older men: Future research and current practice recommendations
-
Liu PY, Swerdloff RS, and Veldhuis JD. The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations. J Clin Endocrinol Metab 89: 4789-4796, 2004.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4789-4796
-
-
Liu, P.Y.1
Swerdloff, R.S.2
Veldhuis, J.D.3
-
30
-
-
0015608662
-
The effect of human chorionic gonadotropin on plasma steroid levels in young and old men
-
Longcope C. The effect of human chorionic gonadotropin on plasma steroid levels in young and old men. Steroids 21: 583-592, 1973.
-
(1973)
Steroids
, vol.21
, pp. 583-592
-
-
Longcope, C.1
-
31
-
-
0018763704
-
Production of testosterone, 5 alpha-androstane-3 alpha, 17 beta-diol and androsterone by dispersed testicular interstitial cells and whole testes in vitro
-
Moger WH. Production of testosterone, 5 alpha-androstane-3 alpha, 17 beta-diol and androsterone by dispersed testicular interstitial cells and whole testes in vitro. J Endocrinol 80: 321-332, 1979.
-
(1979)
J Endocrinol
, vol.80
, pp. 321-332
-
-
Moger, W.H.1
-
32
-
-
0030744143
-
Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: Progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone
-
Morley JE, Kaiser F, Raum WJ, Perry 3rd HM, Flood JF, Jensen J, Silver AJ, and Roberts E. Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone. Proc Natl Acad Sci USA 94: 7537-7542, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7537-7542
-
-
Morley, J.E.1
Kaiser, F.2
Raum, W.J.3
Perry III, H.M.4
Flood, J.F.5
Jensen, J.6
Silver, A.J.7
Roberts, E.8
-
33
-
-
0028787967
-
Amplified nocturnal luteinizing hormone (LH) secretory burst frequency with selective attenuation of pulsatile (but not basal) testosterone secretion in healthy aged men: Possible Leydig cell desensitization to endogenous LH signaling-a clinical research center study
-
Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, and Veldhuis JD. Amplified nocturnal luteinizing hormone (LH) secretory burst frequency with selective attenuation of pulsatile (but not basal) testosterone secretion in healthy aged men: possible Leydig cell desensitization to endogenous LH signaling-a clinical research center study. J Clin Endocrinol Metab 80: 3025-3031, 1995.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3025-3031
-
-
Mulligan, T.1
Iranmanesh, A.2
Gheorghiu, S.3
Godschalk, M.4
Veldhuis, J.D.5
-
34
-
-
0030723197
-
Aging alters feedforward and feedback linkages between LH and testosterone in healthy men
-
Mulligan T, Iranmanesh A, Johnson ML, Straume M, and Veldhuis JD. Aging alters feedforward and feedback linkages between LH and testosterone in healthy men. Am J Physiol Regul Integr Comp Physiol 273: R1407-R1413, 1997.
-
(1997)
Am J Physiol Regul Integr Comp Physiol
, vol.273
-
-
Mulligan, T.1
Iranmanesh, A.2
Johnson, M.L.3
Straume, M.4
Veldhuis, J.D.5
-
35
-
-
0032879225
-
Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig-cell) defects in the healthy aging male gonadotropic axis
-
Mulligan T, Iranmanesh A, Kerzner R, Demers LW, and Veldhuis JD. Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig-cell) defects in the healthy aging male gonadotropic axis. Eur J Endocrinol 141: 257-266, 1999.
-
(1999)
Eur J Endocrinol
, vol.141
, pp. 257-266
-
-
Mulligan, T.1
Iranmanesh, A.2
Kerzner, R.3
Demers, L.W.4
Veldhuis, J.D.5
-
36
-
-
0035187808
-
Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male
-
Mulligan T, Iranmanesh A, and Veldhuis JD. Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male. J Clin Endocrinol Metab 86: 5547-5553, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5547-5553
-
-
Mulligan, T.1
Iranmanesh, A.2
Veldhuis, J.D.3
-
37
-
-
0019350631
-
Age-related changes in the feedback regulation of gonadotrophin secretion by sex steroids in men
-
Muta K, Kato K, Akamine Y, and Ibayashi H. Age-related changes in the feedback regulation of gonadotrophin secretion by sex steroids in men. Acta Endocrinol 96: 154-162, 1981.
-
(1981)
Acta Endocrinol
, vol.96
, pp. 154-162
-
-
Muta, K.1
Kato, K.2
Akamine, Y.3
Ibayashi, H.4
-
38
-
-
84987592449
-
The aging Leydig cell. III. Gonadotropin stimulation in men
-
Nankin HR, Lin T, and Murono EP. The aging Leydig cell. III. Gonadotropin stimulation in men. J Androl 2: 181-186, 1981.
-
(1981)
J Androl
, vol.2
, pp. 181-186
-
-
Nankin, H.R.1
Lin, T.2
Murono, E.P.3
-
39
-
-
0021123879
-
Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men
-
Neaves WB, Johnson L, Porter JC, Parker, CR Jr, and Petty CS. Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men. J Clin Endocrinol Metab 59: 756-763, 1984.
-
(1984)
J Clin Endocrinol Metab
, vol.59
, pp. 756-763
-
-
Neaves, W.B.1
Johnson, L.2
Porter, J.C.3
Parker Jr., C.R.4
Petty, C.S.5
-
40
-
-
0025269960
-
Persistence of concordant LH, testosterone and alpha subunit pulses following LHRH antagonist administration in normal men
-
Pavlou SN, Veldhuis JD, Lindner J, Souza KH, Urban RJ, Rivier JE, Vale WW, and Stallard DJ. Persistence of concordant LH, testosterone and alpha subunit pulses following LHRH antagonist administration in normal men. J Clin Endocrinol Metab 70: 1472-1478, 1990.
-
(1990)
J Clin Endocrinol Metab
, vol.70
, pp. 1472-1478
-
-
Pavlou, S.N.1
Veldhuis, J.D.2
Lindner, J.3
Souza, K.H.4
Urban, R.J.5
Rivier, J.E.6
Vale, W.W.7
Stallard, D.J.8
-
41
-
-
0030450771
-
Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males
-
Pincus SM, Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, and Veldhuis JD. Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males. Proc Natl Acad Sci USA 93: 14100-14105, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14100-14105
-
-
Pincus, S.M.1
Mulligan, T.2
Iranmanesh, A.3
Gheorghiu, S.4
Godschalk, M.5
Veldhuis, J.D.6
-
42
-
-
0026463874
-
Endocrine effects and pharmacokinetic characteristics of a potent new gonadotropin-releasing hormone antagonist (Ganirelix) with minimal histamine-releasing properties: Studies in postmenopausal women
-
Rabinovici J, Rothman P, Monroe SE, Nerenberg C, and Jaffe RB. Endocrine effects and pharmacokinetic characteristics of a potent new gonadotropin- releasing hormone antagonist (Ganirelix) with minimal histamine-releasing properties: studies in postmenopausal women. J Clin Endocrinol Metab 75: 1220-1225, 1992.
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 1220-1225
-
-
Rabinovici, J.1
Rothman, P.2
Monroe, S.E.3
Nerenberg, C.4
Jaffe, R.B.5
-
43
-
-
0016236849
-
Further studies on Leydig cell response to human choriogonadotropin
-
Reubens R, Dhondt M, and Vermeulen A. Further studies on Leydig cell response to human choriogonadotropin. J Clin Endocrinol Metab 39: 40-45, 1976.
-
(1976)
J Clin Endocrinol Metab
, vol.39
, pp. 40-45
-
-
Reubens, R.1
Dhondt, M.2
Vermeulen, A.3
-
44
-
-
0028130155
-
Leydig cells: Endocrine, paracrine, and autocrine regulation
-
Saez JM. Leydig cells: endocrine, paracrine, and autocrine regulation. Endocr Rev 15: 574-626, 1994.
-
(1994)
Endocr Rev
, vol.15
, pp. 574-626
-
-
Saez, J.M.1
-
45
-
-
0016798380
-
Effects of castration and gonadal steroids on serum luteinizing hormone and prolactin in old and young rats
-
Shaar CJ, Euker JS, Riegle GD, and Meites J. Effects of castration and gonadal steroids on serum luteinizing hormone and prolactin in old and young rats. J Endocrinol 66: 45-51, 1974.
-
(1974)
J Endocrinol
, vol.66
, pp. 45-51
-
-
Shaar, C.J.1
Euker, J.S.2
Riegle, G.D.3
Meites, J.4
-
46
-
-
0006171740
-
Different responses of gonadotropin-releasing hormone (GnRH) release to glutamate receptor agonists during aging
-
Sortino MA, Aleppo G, Scapagnini U, and Canonico PL. Different responses of gonadotropin-releasing hormone (GnRH) release to glutamate receptor agonists during aging. Brain Res Bull 41: 359-362, 1996.
-
(1996)
Brain Res Bull
, vol.41
, pp. 359-362
-
-
Sortino, M.A.1
Aleppo, G.2
Scapagnini, U.3
Canonico, P.L.4
-
47
-
-
0016296729
-
Declining testicular function with age, hormonal and clinical correlates
-
Stearns EL, MacDonald JA, Kaufman BJ, Padua R, Lucman T, Winter JSD, and Faiman C. Declining testicular function with age, hormonal and clinical correlates. Am J Med 57: 761-766, 1974.
-
(1974)
Am J Med
, vol.57
, pp. 761-766
-
-
Stearns, E.L.1
MacDonald, J.A.2
Kaufman, B.J.3
Padua, R.4
Lucman, T.5
Winter, J.S.D.6
Faiman, C.7
-
48
-
-
0023550187
-
The effects of aging in normal men on bioavailable testosterone and luteinizing hormone secretion: Response to clomiphene citrate
-
Tenover JS, Matsumoto AM, Plymate SR, and Bremner WJ. The effects of aging in normal men on bioavailable testosterone and luteinizing hormone secretion: response to clomiphene citrate. J Clin Endocrinol Metab 65: 1118-1125, 1987.
-
(1987)
J Clin Endocrinol Metab
, vol.65
, pp. 1118-1125
-
-
Tenover, J.S.1
Matsumoto, A.M.2
Plymate, S.R.3
Bremner, W.J.4
-
49
-
-
0023954666
-
Contemporary aspects of discrete peak detection algorithms. 1. The paradigm of the luteinizing hormone pulse signal in men
-
Urban RJ, Evans WS, Rogol AD, Kaiser DL, Johnson ML, and Veldhuis JD. Contemporary aspects of discrete peak detection algorithms. 1. The paradigm of the luteinizing hormone pulse signal in men. Endocr Rev 9: 3-37, 1988.
-
(1988)
Endocr Rev
, vol.9
, pp. 3-37
-
-
Urban, R.J.1
Evans, W.S.2
Rogol, A.D.3
Kaiser, D.L.4
Johnson, M.L.5
Veldhuis, J.D.6
-
50
-
-
0023448602
-
The pituitary gland secretes in bursts: Appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations
-
Veldhuis JD, Cartoon ML, and Johnson ML. The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci USA 84: 7686-7690, 1987.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7686-7690
-
-
Veldhuis, J.D.1
Cartoon, M.L.2
Johnson, M.L.3
-
51
-
-
0022551868
-
Metabolic clearance of biologically active luteinizing hormone in man
-
Veldhuis JD, Fraioli F, Rogol AD, and Dufau ML. Metabolic clearance of biologically active luteinizing hormone in man. J Clin Invest 77: 1122-1128, 1986.
-
(1986)
J Clin Invest
, vol.77
, pp. 1122-1128
-
-
Veldhuis, J.D.1
Fraioli, F.2
Rogol, A.D.3
Dufau, M.L.4
-
52
-
-
4544352591
-
Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men
-
Veldhuis JD and Iranmanesh A. Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men. J Clin Endocrinol Metab 89: 4474-4479, 2004.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4474-4479
-
-
Veldhuis, J.D.1
Iranmanesh, A.2
-
53
-
-
0034457243
-
Older men manifest multifold synchrony disruption of reproductive neurohormone outflow
-
Veldhuis JD, Iranmanesh A, Godschalk M, and Mulligan T. Older men manifest multifold synchrony disruption of reproductive neurohormone outflow. J Clin Endocrinol Metab 85: 1477-1486, 2000.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 1477-1486
-
-
Veldhuis, J.D.1
Iranmanesh, A.2
Godschalk, M.3
Mulligan, T.4
-
54
-
-
11244304287
-
An ensemble perspective of aging-related hypoandrogenemia in men
-
edited by Winters SJ. Totowa, NJ: Humana
-
Veldhuis JD, Iranmanesh A, and Keenan DM. An ensemble perspective of aging-related hypoandrogenemia in men. In: Male Hypogonadism: Basic, Clinical, and Theoretical Principles., edited by Winters SJ. Totowa, NJ: Humana, 2004. p. 261-284.
-
Male Hypogonadism: Basic, Clinical, and Theoretical Principles
, vol.2004
, pp. 261-284
-
-
Veldhuis, J.D.1
Iranmanesh, A.2
Keenan, D.M.3
-
55
-
-
0033304566
-
Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men
-
Veldhuis JD, Iranmanesh A, Mulligan T, and Pincus SM. Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men. J Clin Endocrinol Metab 84: 3498-3505, 1999.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3498-3505
-
-
Veldhuis, J.D.1
Iranmanesh, A.2
Mulligan, T.3
Pincus, S.M.4
-
56
-
-
0022447036
-
Cluster analysis: A simple, versatile and robust algorithm for endocrine pulse detection
-
Veldhuis JD and Johnson ML. Cluster analysis: a simple, versatile and robust algorithm for endocrine pulse detection. Am J Physiol Endocrinol Metab 250: E486-E493, 1986.
-
(1986)
Am J Physiol Endocrinol Metab
, vol.250
-
-
Veldhuis, J.D.1
Johnson, M.L.2
-
57
-
-
77957099053
-
Specific methodological approaches to selected contemporary issues in deconvolution analysis of pulsatile neuroendocrine data
-
Veldhuis JD and Johnson ML. Specific methodological approaches to selected contemporary issues in deconvolution analysis of pulsatile neuroendocrine data. Methods Neurosci 28: 25-92, 1995.
-
(1995)
Methods Neurosci
, vol.28
, pp. 25-92
-
-
Veldhuis, J.D.1
Johnson, M.L.2
-
58
-
-
0024827270
-
Pathophysiological features of the pulsatile secretion of biologically active luteinizing hormone in man
-
Veldhuis JD, Urban RJ, Beitins I, Blizzard RM, Johnson ML, and Dufau ML. Pathophysiological features of the pulsatile secretion of biologically active luteinizing hormone in man. J Steroid Biochem 33: 739-750, 1989.
-
(1989)
J Steroid Biochem
, vol.33
, pp. 739-750
-
-
Veldhuis, J.D.1
Urban, R.J.2
Beitins, I.3
Blizzard, R.M.4
Johnson, M.L.5
Dufau, M.L.6
-
59
-
-
0026762786
-
Attenuation of luteinizing hormone secretory burst amplitude is a proximate basis for the hypoandrogenism of healthy aging in men
-
Veldhuis JD, Urban RJ, Lizarralde G, Johnson ML, and Iranmanesh A. Attenuation of luteinizing hormone secretory burst amplitude is a proximate basis for the hypoandrogenism of healthy aging in men. J Clin Endocrinol Metab 75: 52-58, 1992.
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 52-58
-
-
Veldhuis, J.D.1
Urban, R.J.2
Lizarralde, G.3
Johnson, M.L.4
Iranmanesh, A.5
-
60
-
-
15444372939
-
Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men
-
Veldhuis JD, Veldhuis NJ, Keenan DM, and Iranmanesh A. Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men. Am J Physiol Endocrinol Metab 288: E775-E781, 2005.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Veldhuis, J.D.1
Veldhuis, N.J.2
Keenan, D.M.3
Iranmanesh, A.4
-
61
-
-
0035095288
-
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men
-
Veldhuis JD, Zwart A, Mulligan T, and Iranmanesh A. Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men. J Clin Endocrinol Metab 86: 529-535, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 529-535
-
-
Veldhuis, J.D.1
Zwart, A.2
Mulligan, T.3
Iranmanesh, A.4
-
62
-
-
0024545519
-
A new look at the andropause: Altered function of the gonadotrophs
-
Vermeulen A, Deslypere JP, and De Meirleir K. A new look at the andropause: altered function of the gonadotrophs. J Steroid Biochem 32: 163-165, 1989.
-
(1989)
J Steroid Biochem
, vol.32
, pp. 163-165
-
-
Vermeulen, A.1
Deslypere, J.P.2
De Meirleir, K.3
-
63
-
-
0018976513
-
Comparison of androgen levels in ram rete testis fluid, testicular lymph and spermatic venous blood plasma: Evidence for a regulatory mechanism in the seminiferous tubules
-
Voglmayr JK, Roberson C, and Musto NA. Comparison of androgen levels in ram rete testis fluid, testicular lymph and spermatic venous blood plasma: evidence for a regulatory mechanism in the seminiferous tubules. Biol Reprod 23: 29-39, 1980.
-
(1980)
Biol Reprod
, vol.23
, pp. 29-39
-
-
Voglmayr, J.K.1
Roberson, C.2
Musto, N.A.3
-
64
-
-
0021713004
-
The gonadotropin-suppressive activity of androgen is increased in elderly men
-
Winters SJ, Sherins RJ, and Troen P. The gonadotropin-suppressive activity of androgen is increased in elderly men. Metabolism 33: 1052-1059, 1984.
-
(1984)
Metabolism
, vol.33
, pp. 1052-1059
-
-
Winters, S.J.1
Sherins, R.J.2
Troen, P.3
-
65
-
-
0020385669
-
Episodic luteinizing hormone (LH) secretion and the response of LH and follicle-stimulating hormone to LH-releasing hormone in aged men: Evidence for coexistent primary testicular insufficiency and an impairment in gonadotropin secretion
-
Winters SJ and Troen P. Episodic luteinizing hormone (LH) secretion and the response of LH and follicle-stimulating hormone to LH-releasing hormone in aged men: evidence for coexistent primary testicular insufficiency and an impairment in gonadotropin secretion. J Clin Endocrinol Metab 55: 560-565, 1982.
-
(1982)
J Clin Endocrinol Metab
, vol.55
, pp. 560-565
-
-
Winters, S.J.1
Troen, P.2
-
66
-
-
0344823859
-
The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis
-
Zhang FP, Pakarainen T, Poutanen M, Toppari J, and Huhtaniemi I. The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. Proc Natl Acad Sci USA 100: 13692-13697, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13692-13697
-
-
Zhang, F.P.1
Pakarainen, T.2
Poutanen, M.3
Toppari, J.4
Huhtaniemi, I.5
-
67
-
-
0029856760
-
Contrasts in the gonadotropin-releasing dose-response relationships for luteinizing hormone, follicle-stimulating hormone, and alpha-subunit release in young versus older men: Appraisal with high-specificity immunodiometric assay and deconvolution analysis
-
Zwart AD, Urban RJ, Odell WD, and Veldhuis JD. Contrasts in the gonadotropin-releasing dose-response relationships for luteinizing hormone, follicle-stimulating hormone, and alpha-subunit release in young versus older men: appraisal with high-specificity immunodiometric assay and deconvolution analysis. Eur J Endocrinol 135: 399-406, 1996.
-
(1996)
Eur J Endocrinol
, vol.135
, pp. 399-406
-
-
Zwart, A.D.1
Urban, R.J.2
Odell, W.D.3
Veldhuis, J.D.4
|