메뉴 건너뛰기




Volumn 26, Issue 2, 2015, Pages 423-431

SND-117, a sinomenine bivalent alleviates type II collagen-induced arthritis in mice

Author keywords

Collagen induced arthritis; Cytokines; Fibroblast like synovial cells; NF B; Sinomenine bivalent; SND 117

Indexed keywords

ANTIRHEUMATIC AGENT; AUTACOID; COLLAGEN TYPE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MORPHINAN DERIVATIVE; SINOMENINE;

EID: 84937760220     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.04.006     Document Type: Article
Times cited : (25)

References (52)
  • 2
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNFα therapy of rheumatoid arthritis: What have we learned?
    • M. Feldmann, and R.N. Maini Anti-TNFα therapy of rheumatoid arthritis: what have we learned? Annu Rev Immunol. 19 2001 163 196
    • (2001) Annu Rev Immunol. , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 4
    • 84906097535 scopus 로고    scopus 로고
    • Rheumatoid arthritis susceptibility genes: An overview
    • I. Korczowska Rheumatoid arthritis susceptibility genes: an overview World J. Orthop. 5 4 2014 544 549
    • (2014) World J. Orthop. , vol.5 , Issue.4 , pp. 544-549
    • Korczowska, I.1
  • 5
    • 20244385126 scopus 로고    scopus 로고
    • New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility
    • S.T. du Montcel, L. Michou, E. Petit-Teixeira, J. Osorio, I. Lemaire, and S. Lasbleiz New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility Arthritis Rheum. 52 2005 1063 1068
    • (2005) Arthritis Rheum. , vol.52 , pp. 1063-1068
    • Du Montcel, S.T.1    Michou, L.2    Petit-Teixeira, E.3    Osorio, J.4    Lemaire, I.5    Lasbleiz, S.6
  • 6
    • 84855928565 scopus 로고    scopus 로고
    • Associations of HLA-shared epitope, anti-citrullinated peptide antibodies and lifestyle-related factors in Hungarian patients with rheumatoid arthritis: Data from the first Central-Eastern European cohort
    • T. Besenyei, A. Gyetvai, Z. Szabó, A. Fekete, A. Kapitány, and P. Szodoray Associations of HLA-shared epitope, anti-citrullinated peptide antibodies and lifestyle-related factors in Hungarian patients with rheumatoid arthritis: data from the first Central-Eastern European cohort Joint Bone Spine 78 2011 652 653
    • (2011) Joint Bone Spine , vol.78 , pp. 652-653
    • Besenyei, T.1    Gyetvai, A.2    Szabó, Z.3    Fekete, A.4    Kapitány, A.5    Szodoray, P.6
  • 7
    • 33645317378 scopus 로고    scopus 로고
    • The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis
    • A. Hinks, J. Worthington, and W. Thomson The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis Rheumatology (Oxford) 45 2006 365 368
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 365-368
    • Hinks, A.1    Worthington, J.2    Thomson, W.3
  • 8
    • 69449090215 scopus 로고    scopus 로고
    • Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody negative rheumatoid arthritis in a large UK Caucasian population
    • A.W. Morgan, W. Thomson, S.G. Martin, A.M. Carter, H.A. Erlich, and A. Barton Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody negative rheumatoid arthritis in a large UK Caucasian population Arthritis Rheum. 60 2009 2565 2576
    • (2009) Arthritis Rheum. , vol.60 , pp. 2565-2576
    • Morgan, A.W.1    Thomson, W.2    Martin, S.G.3    Carter, A.M.4    Erlich, H.A.5    Barton, A.6
  • 9
    • 34250183488 scopus 로고    scopus 로고
    • PADI4 polymorphisms and rheumatoid arthritis susceptibility
    • Y.H. Lee, Y.H. Rho, S.J. Choi, J.D. Ji, and G.G. Song PADI4 polymorphisms and rheumatoid arthritis susceptibility Rheumatol. Int. 27 2007 827 833
    • (2007) Rheumatol. Int. , vol.27 , pp. 827-833
    • Lee, Y.H.1    Rho, Y.H.2    Choi, S.J.3    Ji, J.D.4    Song, G.G.5
  • 11
    • 84906076440 scopus 로고    scopus 로고
    • Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications
    • L. Magyari, D. Varszegi, E. Kovesdi, P. Sarlos, B. Farago, and A. Javorhazy Interleukins and interleukin receptors in rheumatoid arthritis: research, diagnostics and clinical implications World J. Orthop. 5 4 2014 516 536
    • (2014) World J. Orthop. , vol.5 , Issue.4 , pp. 516-536
    • Magyari, L.1    Varszegi, D.2    Kovesdi, E.3    Sarlos, P.4    Farago, B.5    Javorhazy, A.6
  • 12
    • 84908083191 scopus 로고    scopus 로고
    • Defining populations at risk of rheumatoid arthritis: The first steps to prevention
    • L. Hunt, and P. Emery Defining populations at risk of rheumatoid arthritis: the first steps to prevention Nat. Rev. Rheumatol. 10 2014 521 530
    • (2014) Nat. Rev. Rheumatol. , vol.10 , pp. 521-530
    • Hunt, L.1    Emery, P.2
  • 13
    • 84973273197 scopus 로고    scopus 로고
    • Exciting times for RA research
    • P. Emery Exciting times for RA research Nat. Rev. Rheumatol. 2014 10.1038/nrrheum
    • (2014) Nat. Rev. Rheumatol.
    • Emery, P.1
  • 14
    • 84863261665 scopus 로고    scopus 로고
    • Activation of PI3K/Akt and ERK signaling pathways antagonized sinomenine-induced lung cancer cell apoptosis
    • L. Zhou, H. Luan, Q. Liu, T. Jiang, H. Liang, and X. Dong Activation of PI3K/Akt and ERK signaling pathways antagonized sinomenine-induced lung cancer cell apoptosis Mol. Med. Rep. 5 5 2012 1256 1260
    • (2012) Mol. Med. Rep. , vol.5 , Issue.5 , pp. 1256-1260
    • Zhou, L.1    Luan, H.2    Liu, Q.3    Jiang, T.4    Liang, H.5    Dong, X.6
  • 15
    • 84873659641 scopus 로고    scopus 로고
    • Sinomenine hydrochloride inhibits human hepatocellular carcinoma cell growth in vitro and in vivo: Involvement of cell cycle arrest and apoptosis induction
    • X.L. Lu, J. Zeng, Y.L. Chen, P.M. He, M.X. Wen, and M.D. Ren Sinomenine hydrochloride inhibits human hepatocellular carcinoma cell growth in vitro and in vivo: involvement of cell cycle arrest and apoptosis induction Int. J. Oncol. 42 1 2013 229 238
    • (2013) Int. J. Oncol. , vol.42 , Issue.1 , pp. 229-238
    • Lu, X.L.1    Zeng, J.2    Chen, Y.L.3    He, P.M.4    Wen, M.X.5    Ren, M.D.6
  • 16
    • 84886771776 scopus 로고    scopus 로고
    • Sinomenine sensitizes gastric cancer cells to 5-fluorouracil in vitro and in vivo
    • F. Liao, Z. Yang, X. Lu, X. Guo, and W. Dong Sinomenine sensitizes gastric cancer cells to 5-fluorouracil in vitro and in vivo Oncol. Lett. 6 6 2013 1604 1610
    • (2013) Oncol. Lett. , vol.6 , Issue.6 , pp. 1604-1610
    • Liao, F.1    Yang, Z.2    Lu, X.3    Guo, X.4    Dong, W.5
  • 17
    • 84889577438 scopus 로고    scopus 로고
    • Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma
    • J. Wang, Z.R. Yang, W.G. Dong, J.X. Zhang, X.F. Guo, and J. Song Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma World J. Gastroenterol. 19 45 2013 8292 8300
    • (2013) World J. Gastroenterol. , vol.19 , Issue.45 , pp. 8292-8300
    • Wang, J.1    Yang, Z.R.2    Dong, W.G.3    Zhang, J.X.4    Guo, X.F.5    Song, J.6
  • 18
    • 84893086918 scopus 로고    scopus 로고
    • Sinomenine reverses multidrug resistance in bladder cancer cells via P-glycoprotein-dependent and independent manners
    • Y. Chen, L. Zhang, X. Lu, K. Wu, J. Zeng, and Y. Gao Sinomenine reverses multidrug resistance in bladder cancer cells via P-glycoprotein-dependent and independent manners Pharmazie 69 1 2014 48 54
    • (2014) Pharmazie , vol.69 , Issue.1 , pp. 48-54
    • Chen, Y.1    Zhang, L.2    Lu, X.3    Wu, K.4    Zeng, J.5    Gao, Y.6
  • 19
    • 34547970699 scopus 로고    scopus 로고
    • Vasodilatation induced by sinomenine lowers blood pressure in spontaneously hypertensive rats
    • P.Y. Lee, W. Chen, I.M. Liu, and J.T. Cheng Vasodilatation induced by sinomenine lowers blood pressure in spontaneously hypertensive rats Clin. Exp. Pharmacol. Physiol. 34 10 2007 979 984
    • (2007) Clin. Exp. Pharmacol. Physiol. , vol.34 , Issue.10 , pp. 979-984
    • Lee, P.Y.1    Chen, W.2    Liu, I.M.3    Cheng, J.T.4
  • 20
    • 0037446705 scopus 로고    scopus 로고
    • Sinomenine blocks tissue remodeling in a rat model of chronic cardiac allograft rejection
    • W. Mark, S. Schneeberger, R. Seiler, D.M. Stroka, A. Amberger, and F. Offner Sinomenine blocks tissue remodeling in a rat model of chronic cardiac allograft rejection Transplantation 75 7 2003 940 945
    • (2003) Transplantation , vol.75 , Issue.7 , pp. 940-945
    • Mark, W.1    Schneeberger, S.2    Seiler, R.3    Stroka, D.M.4    Amberger, A.5    Offner, F.6
  • 22
    • 84890118264 scopus 로고    scopus 로고
    • Analgesic effect of sinomenine in rodents after inflammation and nerve injury
    • T. Gao, J. Hao, Z. Wiesenfeld-Hallin, D.Q. Wang, and X.J. Xu Analgesic effect of sinomenine in rodents after inflammation and nerve injury Eur. J. Pharmacol. 721 3 2013 5 11
    • (2013) Eur. J. Pharmacol. , vol.721 , Issue.3 , pp. 5-11
    • Gao, T.1    Hao, J.2    Wiesenfeld-Hallin, Z.3    Wang, D.Q.4    Xu, X.J.5
  • 23
    • 84885416408 scopus 로고    scopus 로고
    • Sinomenine protects mice against ischemia reperfusion induced renal injury by attenuating inflammatory response and tubular cell apoptosis
    • Z. Zhao, R. Guan, S. Song, M. Zhang, F. Liu, and M. Guo Sinomenine protects mice against ischemia reperfusion induced renal injury by attenuating inflammatory response and tubular cell apoptosis Int. J. Clin. Exp. Pathol. 6 9 2013 1702 1712
    • (2013) Int. J. Clin. Exp. Pathol. , vol.6 , Issue.9 , pp. 1702-1712
    • Zhao, Z.1    Guan, R.2    Song, S.3    Zhang, M.4    Liu, F.5    Guo, M.6
  • 24
    • 84867932436 scopus 로고    scopus 로고
    • Anti-inflammatory effect of sinomenine by inhibition of pro-inflammatory mediators in PMA plus A23187-stimulated HMC-1 cells
    • Y.C. Oh, O.H. Kang, S.B. Kim, S.H. Mun, C.B. Park, and Y.G. Kim Anti-inflammatory effect of sinomenine by inhibition of pro-inflammatory mediators in PMA plus A23187-stimulated HMC-1 cells Eur. Rev. Med. Pharmacol. Sci. 16 9 2012 1184 1191
    • (2012) Eur. Rev. Med. Pharmacol. Sci. , vol.16 , Issue.9 , pp. 1184-1191
    • Oh, Y.C.1    Kang, O.H.2    Kim, S.B.3    Mun, S.H.4    Park, C.B.5    Kim, Y.G.6
  • 26
    • 54249103265 scopus 로고    scopus 로고
    • Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: A systematic review and meta-analysis
    • M. Xu, L. Liu, C. Qi, B. Deng, and X. Cai Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: a systematic review and meta-analysis Planta Med. 74 12 2008 1423 1429
    • (2008) Planta Med. , vol.74 , Issue.12 , pp. 1423-1429
    • Xu, M.1    Liu, L.2    Qi, C.3    Deng, B.4    Cai, X.5
  • 27
    • 71649110020 scopus 로고    scopus 로고
    • Modification of poorly bioactive sinomenine into more potent immunosuppressive agents by embedding of drug-like fragments
    • Y. Lou, H. Zhou, J. Zou, L. Yan, E. Bi, and B. Sun Modification of poorly bioactive sinomenine into more potent immunosuppressive agents by embedding of drug-like fragments Tetrahedron Lett. 51 2010 485 488
    • (2010) Tetrahedron Lett. , vol.51 , pp. 485-488
    • Lou, Y.1    Zhou, H.2    Zou, J.3    Yan, L.4    Bi, E.5    Sun, B.6
  • 28
    • 72949115494 scopus 로고    scopus 로고
    • Novel sinomenine derivative 1032 improves immune suppression in experimental autoimmune encephalomyelitis
    • L.C. Yan, E.G. Bi, Y.T. Lou, X.D. Wu, Z.D. Liu, and J. Zou Novel sinomenine derivative 1032 improves immune suppression in experimental autoimmune encephalomyelitis Biochem. Biophys. Res. Commun. 391 1 2010 1093 1098
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , Issue.1 , pp. 1093-1098
    • Yan, L.C.1    Bi, E.G.2    Lou, Y.T.3    Wu, X.D.4    Liu, Z.D.5    Zou, J.6
  • 29
    • 84862779901 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory agents
    • P. Teng, H.L. Liu, L. Zhang, Y. Sun, Q. Xu, and J.X. Li Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory agents Eur. J. Med. Chem. 50 2012 63 74
    • (2012) Eur. J. Med. Chem. , vol.50 , pp. 63-74
    • Teng, P.1    Liu, H.L.2    Zhang, L.3    Sun, Y.4    Xu, Q.5    Li, J.X.6
  • 32
    • 84889660793 scopus 로고    scopus 로고
    • Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice
    • D. Impellizzeri, E. Esposito, R. Di Paola, A. Ahmad, M. Campolo, and A. Peli Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice Arthritis Res. Ther. 15 6 2013 R192
    • (2013) Arthritis Res. Ther. , vol.15 , Issue.6 , pp. R192
    • Impellizzeri, D.1    Esposito, E.2    Di Paola, R.3    Ahmad, A.4    Campolo, M.5    Peli, A.6
  • 33
    • 84919619450 scopus 로고    scopus 로고
    • Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products
    • J. Ma, H. Hui Shi, C. Mi, H.L. Li, J.J. Lee, and X. Jin Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products Int. Immunopharmacol. 24 2015 147 152
    • (2015) Int. Immunopharmacol. , vol.24 , pp. 147-152
    • Ma, J.1    Hui Shi, H.2    Mi, C.3    Li, H.L.4    Lee, J.J.5    Jin, X.6
  • 34
    • 84894237586 scopus 로고    scopus 로고
    • Targeting TNF-A and NF-kB activation by bee venom: Role in suppressing adjuvant induced arthritis and methotrexate hepatotoxicity in rats
    • S.F. Darwish, W.M. El-Bakly, H.M. Arafa, and E. El-Demerdash Targeting TNF-a and NF-kB activation by bee venom: role in suppressing adjuvant induced arthritis and methotrexate hepatotoxicity in rats PLoS ONE 8 11 2013 e79284
    • (2013) PLoS ONE , vol.8 , Issue.11 , pp. e79284
    • Darwish, S.F.1    El-Bakly, W.M.2    Arafa, H.M.3    El-Demerdash, E.4
  • 35
    • 33645230648 scopus 로고    scopus 로고
    • Isolation and characterization of synovial cells from the human temporomandibular joint
    • H. Nagai, Y. Miyamoto, A. Nakata, S. Hatakeyama, Y. Iwanami, and M. Fukuda Isolation and characterization of synovial cells from the human temporomandibular joint J. Oral Pathol. Med. 35 2 2006 104 110
    • (2006) J. Oral Pathol. Med. , vol.35 , Issue.2 , pp. 104-110
    • Nagai, H.1    Miyamoto, Y.2    Nakata, A.3    Hatakeyama, S.4    Iwanami, Y.5    Fukuda, M.6
  • 36
    • 34247581709 scopus 로고    scopus 로고
    • Fibroblast-like synovial cells from normal and inflamed knee joints differently affect the expression of pain-related receptors in sensory neurons: A co-culture study
    • G.S. von Banchet, J. Richter, M. Hückel, C. Rose, R. Bräuer, and H.G. Schaible Fibroblast-like synovial cells from normal and inflamed knee joints differently affect the expression of pain-related receptors in sensory neurons: a co-culture study Arthritis Res. Ther. 9 1 2007 R6
    • (2007) Arthritis Res. Ther. , vol.9 , Issue.1 , pp. R6
    • Von Banchet, G.S.1    Richter, J.2    Hückel, M.3    Rose, C.4    Bräuer, R.5    Schaible, H.G.6
  • 37
    • 84910086589 scopus 로고    scopus 로고
    • Experience with subcutaneous abatacept for rheumatoid arthritis: An update for clinicians
    • M.M. Khraishi Experience with subcutaneous abatacept for rheumatoid arthritis: an update for clinicians Ther. Adv. Musculoskelet. Dis. 6 5 2014 159 168
    • (2014) Ther. Adv. Musculoskelet. Dis. , vol.6 , Issue.5 , pp. 159-168
    • Khraishi, M.M.1
  • 38
    • 84907225912 scopus 로고    scopus 로고
    • Effect of combination therapy on joint destruction in rheumatoid arthritis: A network meta-analysis of randomized controlled trials
    • N. Graudal, T. Hubeck-Graudal, S. Tarp, R. Christensen, and G. Jürgens Effect of combination therapy on joint destruction in rheumatoid arthritis: a network meta-analysis of randomized controlled trials PLoS ONE 9 2014 e106408
    • (2014) PLoS ONE , vol.9 , pp. e106408
    • Graudal, N.1    Hubeck-Graudal, T.2    Tarp, S.3    Christensen, R.4    Jürgens, G.5
  • 39
    • 84907023509 scopus 로고    scopus 로고
    • Arthritis, a complex connective and synovial joint destructive autoimmune disease: Animal models of arthritis with varied etiopathology and their significance
    • S.R. Naik, and S.M. Wala Arthritis, a complex connective and synovial joint destructive autoimmune disease: animal models of arthritis with varied etiopathology and their significance J. Postgrad. Med. 60 2014 309 317
    • (2014) J. Postgrad. Med. , vol.60 , pp. 309-317
    • Naik, S.R.1    Wala, S.M.2
  • 40
    • 0242417566 scopus 로고    scopus 로고
    • Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a shiga-like toxin
    • P.I. Kitov, H. Shimizu, S.W. Homans, and D.R. Bundle Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a shiga-like toxin J. Am. Chem. Soc. 125 2003 3284 3294
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 3284-3294
    • Kitov, P.I.1    Shimizu, H.2    Homans, S.W.3    Bundle, D.R.4
  • 41
    • 79956208522 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of unique stereodimers of sinomenine analogues as potential inhibitors of NO production
    • P. Teng, H.L. Liu, Z.S. Deng, Z.B. Shi, Y.M. He, L.L. Feng, Q. Xu, and J.X. Li Synthesis and biological evaluation of unique stereodimers of sinomenine analogues as potential inhibitors of NO production Bioorg. Med. Chem. 19 2011 3096 3104
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 3096-3104
    • Teng, P.1    Liu, H.L.2    Deng, Z.S.3    Shi, Z.B.4    He, Y.M.5    Feng, L.L.6    Xu, Q.7    Li, J.X.8
  • 42
    • 79955713628 scopus 로고    scopus 로고
    • Evaluation of inflammatory change and bone erosion using a murine type II collagen-induced arthritis model
    • S. Choi, Y.A. Lee, S.J. Hong, G.J. Lee, S.W. Kang, and J.H. Park Evaluation of inflammatory change and bone erosion using a murine type II collagen-induced arthritis model Rheumatol. Int. 31 2011 595 603
    • (2011) Rheumatol. Int. , vol.31 , pp. 595-603
    • Choi, S.1    Lee, Y.A.2    Hong, S.J.3    Lee, G.J.4    Kang, S.W.5    Park, J.H.6
  • 43
    • 84906827120 scopus 로고    scopus 로고
    • Rheumatoid arthritis pathophysiology: Update on emerging cytokine and cytokine-associated cell, targets
    • D.E. Furst, and P. Emery Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell, targets Rheumatology (Oxford) 53 2014 1560 1569
    • (2014) Rheumatology (Oxford) , vol.53 , pp. 1560-1569
    • Furst, D.E.1    Emery, P.2
  • 44
    • 84988568901 scopus 로고    scopus 로고
    • Therapeutic effect of daphnetin on the autoimmune arthritis through demethylation of proapoptotic genes in synovial cells
    • K. Shu, N. Kuang, Z. Zhang, Z. Hu, Y. Zhang, and Y. Fu Therapeutic effect of daphnetin on the autoimmune arthritis through demethylation of proapoptotic genes in synovial cells J. Transl. Med. 12 2014 287
    • (2014) J. Transl. Med. , vol.12 , pp. 287
    • Shu, K.1    Kuang, N.2    Zhang, Z.3    Hu, Z.4    Zhang, Y.5    Fu, Y.6
  • 45
    • 84908246310 scopus 로고    scopus 로고
    • Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis
    • B.J.E. de Lange-Brokaar, A. Ioan-Facsinay, E. Yusuf, A.W. Visser, H.M. Kroon, and S.N. Andersen Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis Osteoarthr. Cartil. 22 2014 1606 1613
    • (2014) Osteoarthr. Cartil. , vol.22 , pp. 1606-1613
    • De Lange-Brokaar, B.J.E.1    Ioan-Facsinay, A.2    Yusuf, E.3    Visser, A.W.4    Kroon, H.M.5    Andersen, S.N.6
  • 47
    • 34447324890 scopus 로고    scopus 로고
    • Anti-malarial agent artesunate inhibits TNF-α-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes
    • H. Xu, Y. He, X. Yang, L. Liang, Z. Zhan, and Y. Ye Anti-malarial agent artesunate inhibits TNF-α-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes Rheumatology 46 2007 920 926
    • (2007) Rheumatology , vol.46 , pp. 920-926
    • Xu, H.1    He, Y.2    Yang, X.3    Liang, L.4    Zhan, Z.5    Ye, Y.6
  • 48
    • 84875721405 scopus 로고    scopus 로고
    • Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts
    • A. Lee, Y. Qiao, G. Grigoriev, J. Chen, K.-H. Park-Min, and S.H. Park Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts Arthritis Rheum. 65 2013 928 938
    • (2013) Arthritis Rheum. , vol.65 , pp. 928-938
    • Lee, A.1    Qiao, Y.2    Grigoriev, G.3    Chen, J.4    Park-Min, K.-H.5    Park, S.H.6
  • 49
    • 82955227633 scopus 로고    scopus 로고
    • The use of conventional disease-modifying anti-rheumatic drugs in established RA
    • M.S. Jurgens, J.W.G. Jacobs, and J.W.J. Bijlsma The use of conventional disease-modifying anti-rheumatic drugs in established RA Best Pract. Res. Clin. Rheumatol. 25 2011 523 533
    • (2011) Best Pract. Res. Clin. Rheumatol. , vol.25 , pp. 523-533
    • Jurgens, M.S.1    Jacobs, J.W.G.2    Bijlsma, J.W.J.3
  • 51
    • 84930382226 scopus 로고    scopus 로고
    • Trojan horses and guided missiles: Targeted therapies in the war on arthritis
    • M. Ferrari, S.C. Onuoha, and C. Pitzalis Trojan horses and guided missiles: targeted therapies in the war on arthritis Nat. Rev. Rheumatol. 2015 10.1038/nrrheum.2015.17
    • (2015) Nat. Rev. Rheumatol.
    • Ferrari, M.1    Onuoha, S.C.2    Pitzalis, C.3
  • 52
    • 77950487586 scopus 로고    scopus 로고
    • Kinase inhibitors attract attention as oral rheumatoid arthritis drugs
    • A. Opar Kinase inhibitors attract attention as oral rheumatoid arthritis drugs Nat. Rev. Drug Discov. 9 2010 257 258
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 257-258
    • Opar, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.