Vasodilatation induced by sinomenine lowers blood pressure in spontaneously hypertensive rats

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 10, 2007, Pages 979-984

  Lee, Ping Ying ^a   Chen, Wency ^b   Liu, I Min ^c   Cheng, Juei Tang ^d  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

^c TAJEN UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Aortic rings; ATP sensitive K+ channels; Cultured aortic smooth muscle cells; Intracellular calcium concentrations; Sinomenine

Indexed keywords

CALCIUM ION; FURA 2; GLIBENCLAMIDE; PHENYLEPHRINE; POTASSIUM CHANNEL; POTASSIUM CHLORIDE; SINOMENINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; HYPERTENSION; MALE; NONHUMAN; RAT; SMOOTH MUSCLE FIBER; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; VASCULAR RING; VASODILATATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AORTA, THORACIC; BLOOD PRESSURE; CELL LINE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUORESCENT DYES; FURA-2; GLYBURIDE; HYPOGLYCEMIC AGENTS; MALE; MORPHINANS; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, INBRED SHR; RATS, WISTAR; VASODILATION;

EID: 34547970699     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04668.x     Document Type: Article

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