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Volumn 460, Issue 3, 2015, Pages 850-856

P2Y purinergic receptor-regulated insulin secretion is mediated by a cAMP/Epac/Kv channel pathway

Author keywords

Cyclic AMP; Diabetes; Insulin secretion; P2Y purinergic receptor; Voltage dependent potassium channels

Indexed keywords

CALCIUM; CYCLIC AMP; EPAC PROTEIN, RAT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INSULIN; POTASSIUM CHANNEL; PURINERGIC P2Y RECEPTOR;

EID: 84937759021     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.121     Document Type: Article
Times cited : (11)

References (23)
  • 1
    • 0027406884 scopus 로고
    • Stimulation of insulin secretion and improvement of glucose tolerance in rat and dog by the P2y-purinoceptor agonist, adenosine-5′-O-(2-thiodiphosphate)
    • D. Hillaire-Buys, G. Bertrand, J. Chapal, R. Puech, G. Ribes, and M.M. Loubatieres-Mariani Stimulation of insulin secretion and improvement of glucose tolerance in rat and dog by the P2y-purinoceptor agonist, adenosine-5′-O-(2-thiodiphosphate) Br. J. Pharmacol. 109 1993 183 187
    • (1993) Br. J. Pharmacol. , vol.109 , pp. 183-187
    • Hillaire-Buys, D.1    Bertrand, G.2    Chapal, J.3    Puech, R.4    Ribes, G.5    Loubatieres-Mariani, M.M.6
  • 3
    • 62649114002 scopus 로고    scopus 로고
    • P2 purinergic signalling in the pancreatic beta-cell: control of insulin secretion and pharmacology
    • P. Petit, A.D. Lajoix, and R. Gross P2 purinergic signalling in the pancreatic beta-cell: control of insulin secretion and pharmacology Eur. J. Pharm. Sci. 37 2009 67 75
    • (2009) Eur. J. Pharm. Sci. , vol.37 , pp. 67-75
    • Petit, P.1    Lajoix, A.D.2    Gross, R.3
  • 6
    • 0042879894 scopus 로고    scopus 로고
    • Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets
    • P.E. MacDonald, and M.B. Wheeler Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets Diabetologia 46 2003 1046 1062
    • (2003) Diabetologia , vol.46 , pp. 1046-1062
    • MacDonald, P.E.1    Wheeler, M.B.2
  • 7
    • 84906921621 scopus 로고    scopus 로고
    • The adenylyl cyclase inhibitor MDL-12,330A potentiates insulin secretion via blockade of voltage-dependent K(+) channels in pancreatic beta cells
    • X. Li, Q. Guo, J. Gao, J. Yang, W. Zhang, Y. Liang, D. Wu, Y. Liu, J. Weng, Q. Li, and Y. Zhang The adenylyl cyclase inhibitor MDL-12,330A potentiates insulin secretion via blockade of voltage-dependent K(+) channels in pancreatic beta cells PloS One 8 2013 e77934
    • (2013) PloS One , vol.8
    • Li, X.1    Guo, Q.2    Gao, J.3    Yang, J.4    Zhang, W.5    Liang, Y.6    Wu, D.7    Liu, Y.8    Weng, J.9    Li, Q.10    Zhang, Y.11
  • 8
    • 0026031105 scopus 로고
    • Adenosine-5′-O-(2-thiodiphosphate) is a potent agonist at P2 purinoceptors mediating insulin secretion from perfused rat pancreas
    • G. Bertrand, J. Chapal, R. Puech, and M.M. Loubatieres-Mariani Adenosine-5′-O-(2-thiodiphosphate) is a potent agonist at P2 purinoceptors mediating insulin secretion from perfused rat pancreas Br. J. Pharmacol. 102 1991 627 630
    • (1991) Br. J. Pharmacol. , vol.102 , pp. 627-630
    • Bertrand, G.1    Chapal, J.2    Puech, R.3    Loubatieres-Mariani, M.M.4
  • 9
    • 9444240944 scopus 로고    scopus 로고
    • P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism
    • A. Farret, M. Vignaud, S. Dietz, J. Vignon, P. Petit, and R. Gross P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism Diabetes 53 Suppl.3 2004 S63 S66
    • (2004) Diabetes , vol.53 , pp. S63-S66
    • Farret, A.1    Vignaud, M.2    Dietz, S.3    Vignon, J.4    Petit, P.5    Gross, R.6
  • 10
    • 0036033776 scopus 로고    scopus 로고
    • P2Y receptor activation enhances insulin release from pancreatic beta-cells by triggering the cyclic AMP/protein kinase A pathway
    • H. Chevassus, A. Roig, C. Belloc, A.D. Lajoix, C. Broca, M. Manteghetti, and P. Petit P2Y receptor activation enhances insulin release from pancreatic beta-cells by triggering the cyclic AMP/protein kinase A pathway Naunyn Schmiedeb. Arch. Pharmacol. 366 2002 464 469
    • (2002) Naunyn Schmiedeb. Arch. Pharmacol. , vol.366 , pp. 464-469
    • Chevassus, H.1    Roig, A.2    Belloc, C.3    Lajoix, A.D.4    Broca, C.5    Manteghetti, M.6    Petit, P.7
  • 11
    • 34548266670 scopus 로고    scopus 로고
    • Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion
    • D.A. Jacobson, A. Kuznetsov, J.P. Lopez, S. Kash, C.E. Ammala, and L.H. Philipson Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion Cell. Metab. 6 2007 229 235
    • (2007) Cell. Metab. , vol.6 , pp. 229-235
    • Jacobson, D.A.1    Kuznetsov, A.2    Lopez, J.P.3    Kash, S.4    Ammala, C.E.5    Philipson, L.H.6
  • 13
    • 84907044034 scopus 로고    scopus 로고
    • Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca in female mouse islets stimulated by glucose and tolbutamide
    • J.C. Henquin, and M. Nenquin Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca in female mouse islets stimulated by glucose and tolbutamide Endocrinology 2014 en20141247
    • (2014) Endocrinology
    • Henquin, J.C.1    Nenquin, M.2
  • 17
    • 0037424363 scopus 로고    scopus 로고
    • Epac-selective cAMP analog 8-pCPT-2′-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells
    • G. Kang, J.W. Joseph, O.G. Chepurny, M. Monaco, M.B. Wheeler, J.L. Bos, F. Schwede, H.G. Genieser, and G.G. Holz Epac-selective cAMP analog 8-pCPT-2′-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells J. Biol. Chem. 278 2003 8279 8285
    • (2003) J. Biol. Chem. , vol.278 , pp. 8279-8285
    • Kang, G.1    Joseph, J.W.2    Chepurny, O.G.3    Monaco, M.4    Wheeler, M.B.5    Bos, J.L.6    Schwede, F.7    Genieser, H.G.8    Holz, G.G.9
  • 19
    • 84874088506 scopus 로고    scopus 로고
    • Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle
    • F. Brette, E. Blandin, C. Simard, R. Guinamard, and L. Salle Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle J. Mol. Cell. Cardiol. 57 2013 96 105
    • (2013) J. Mol. Cell. Cardiol. , vol.57 , pp. 96-105
    • Brette, F.1    Blandin, E.2    Simard, C.3    Guinamard, R.4    Salle, L.5
  • 20
    • 0034601207 scopus 로고    scopus 로고
    • Inhibition of potassium and calcium currents in neurones by molecularly-defined P2Y receptors
    • D.A. Brown, A.K. Filippov, and E.A. Barnard Inhibition of potassium and calcium currents in neurones by molecularly-defined P2Y receptors J. Auton. Nerv. Syst. 81 2000 31 36
    • (2000) J. Auton. Nerv. Syst. , vol.81 , pp. 31-36
    • Brown, D.A.1    Filippov, A.K.2    Barnard, E.A.3
  • 22
    • 0028030954 scopus 로고
    • In vivo and in vitro effects of adenosine-5′-O-(2-thiodiphosphate) on pancreatic hormones in dogs
    • D. Hillaire-Buys, R. Gross, N. Pares-Herbute, G. Ribes, and M.M. Loubatieres-Mariani In vivo and in vitro effects of adenosine-5′-O-(2-thiodiphosphate) on pancreatic hormones in dogs Pancreas 9 1994 646 651
    • (1994) Pancreas , vol.9 , pp. 646-651
    • Hillaire-Buys, D.1    Gross, R.2    Pares-Herbute, N.3    Ribes, G.4    Loubatieres-Mariani, M.M.5
  • 23
    • 0029918010 scopus 로고    scopus 로고
    • Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats
    • J. Tang, W. Pugh, K.S. Polonsky, and H. Zhang Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats Am. J. Physiol. 270 1996 E504 E512
    • (1996) Am. J. Physiol. , vol.270 , pp. E504-E512
    • Tang, J.1    Pugh, W.2    Polonsky, K.S.3    Zhang, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.