P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic β-cell metabolism

Diabetes

Volumn 53, Issue SUPPL. 3, 2004, Pages

  Farret, A ^a   Vignaud, M ^a   Dietz, S ^b   Vignon, J ^a   Petit, P ^a   Gross, René ^a  

^a CNRS   (France)

^b INNODIA SAS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; BOVINE SERUM ALBUMIN; POTASSIUM CHANNEL BLOCKING AGENT; PURINE NUCLEOTIDE; PURINE P2Y RECEPTOR; TOLBUTAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL METABOLISM; CITRIC ACID CYCLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG POTENTIATION; EXTRACELLULAR CALCIUM; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN RELEASE; INSULIN RESPONSE; MALE; MEMBRANE CONDUCTANCE; NONHUMAN; PANCREAS ISLET BETA CELL; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE;

ADENOSINE DIPHOSPHATE; ANIMALS; DIAZOXIDE; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MALE; NITROPRUSSIDE; POTASSIUM CHANNELS; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; THIONUCLEOTIDES;

EID: 9444240944     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.suppl_3.S63     Document Type: Conference Paper

References (28)

1. Loubatières-Mariani MM, Petit P, Chapal J, Hillaire-Buys D, Bertrand G, Ribes G: Effects of purinoceptor agonists on insulin secretion. In Adenosine and Adenine Nucleotides: From Molecular Biology to Integrate Physiology. Belardinelli L, Pelleg A, Eds. Boston, Kluwer Academic Publishers, 1995, p. 337-345
2. 2-purinoceptors on β cell and pancreatic vascular bed. Br J Pharmacol 91:783-787, 1987
3. 2 purinoceptors mediating insulin secretion from perfused rat pancreas. Br J Pharmacol 102:627-630, 1991
4. Petit P, Hillaire-Buys D, Loubatières-Mariani MM, Chapal J: Purinergic receptors and the pharmacology of type 2 diabetes. In Handbook of Experimental Pharmacology: Purinergic and Pyrimidinergic Signaling. Abbrachio MP, Williams M, Eds. Berlin, Springer-Verlag, 2001, p. 377-391
5. 2Y purinoceptor agonist, adenosine-5′-O-(2-thiodiphosphate). Br J Pharmacol 109:183-187, 1993
6. Petit P, Hillaire-Buys D, Manteghetti M, Debrus S, Chapal J, Loubatières-Mariani MM: Evidence for two different types of P2-receptors stimulating insulin secretion from pancreatic B cell. Br J Pharmacol 125:1368-1374, 1998
7. Fernandez-Alvarez J, Hillaire-Buys D, Loubatières-Mariani MM, Gomis R, Petit P: P2 receptor agonists stimulate insulin release from human pancreatic islets. Pancreas 22:69-71, 2001
8. Petit P, Manteghetti M, Puech R, Loubatieres-Mariani MM: ATP and phosphate-modified adenine nucleotide analogs: effects on insulin secretion and calcium uptake. Biochem Pharmacol 36:377-380, 1987
9. Gylfe E, Hellman B: External ATP mimics carbachol in initiating calcium mobilization from pancreatic β-cells conditioned by previous exposure to glucose. Br J Pharmacol 92:281-289, 1987
10. 2+ concentration in clonal insulin-producing RINm5F cells. Biochem J 265:203-211, 1990
11. 2+ concentration in human pancreatic islets and insulinoma cells. FEBS Lett 291:310-314, 1991
12. Petit P, Bertrand G, Schmeer W, Henquin JC: Effects of extracellular nucleotides on the electrical, ionic and secretory events in mouse pancreatic β-cells. Br J Pharmacol 98:875-882, 1989
13. +-dependent and -independent insulin secretion in RINmSF cells. J Biol Chem 266:3449-3457, 1991
14. Chevassus H, Roig A, Belloc C, Lajoix AD, Manteghetti M, Petit P: P2Y-receptor activation enhances insulin release from pancreatic β-cells by triggering the cyclic AMP/protein kinase A pathway. Naunyn Schmiedebergs Arch Pharmacol 366:464-469, 2002
15. Loubatières-Mariani MM, Demalbosc H, Ribes G, Chapal J: Etude expérimentale d'un nouveau sulfamide hypoglycémiant particulièrement actif, le HB 419 ou glibenclamide. Diabetologia 5:1-10, 1969
16. Herbert V, Law KS, Gotlieb CW, Blachier SJ: Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab 25:1375-1384, 1965
17. Tsuura Y, Ishida H, Shinomura T, Nishimura M, Seino Y: Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets. Biochem Biophys Res Commun 252:34-38, 1998
18. Dimmeler S, Lottspeich F, Brune B: Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 267:16771-16774, 1992
19. Brown GC, Cooper CE: Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 356:295-298, 1994
20. Henquin JC: Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 49:1751-1760, 2000
21. + channels in mouse B cells. J Clin Invest 89:1288-1295, 1992
22. Brayden JE: Functional roles of KATP channels in vascular smooth muscle. Clin Exp Pharmacol Physiol 29:312-316, 2002
23. Light PE, Manning Fox JE, Riedel MJ, Wheeler MB: Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism. Mol Endocrinol 16:2135-2144, 2002
24. Lembert N, Joos HC, Wahl LA, Ammon HP, Wahl MA: Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP. Biochem J 354:345-350, 2001
25. Dufer M, Krippeit-Drews P, Buntinas L, Siemen D, Drews G: Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate. Biochem J 368:817-825, 2002
26. Fahien LA, MacDonald MJ: The succinate mechanism of insulin release. Diabetes 51:2669-2676, 2002
27. Metz SA, Rabaglia ME, Stock JB, Kowluru A: Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins. Biochem J 295:31-40, 1993
28. Li G, Regazzi R, Roche E, Wollheim CB: Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells: probable involvement of small GTP-binding proteins. Biochem J 289:379-385, 1993