The adenylyl cyclase inhibitor MDL-12,330A potentiates insulin secretion via blockade of voltage-dependent K(+) channels in pancreatic beta cells.

PloS one

Volumn 8, Issue 10, 2013, Pages

  Li, Xiaodong ^a   Guo, Qing ^b   Gao, Jingying ^b   Yang, Jing ^b   Zhang, Wan ^b   Liang, Yueqin ^b   Wu, Dongmei ^b   Liu, Yunfeng ^b   Weng, Jianping ^b   Li, Qingshan ^b   Zhang, Y ^b  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CYCLIC AMP; GLUCOSE; IMINE; INSULIN; N (2 PHENYLCYCLOPENTYL)AZACYCLOTRIDECAN 2 IMINE; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL; ARTICLE; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ELECTROPHYSIOLOGY; MALE; METABOLISM; PANCREAS ISLET BETA CELL; PATHOLOGY; RAT; SECRETION (PROCESS); SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CELLS, CULTURED; CYCLIC AMP; ELECTROPHYSIOLOGY; GLUCOSE; IMINES; INSULIN; INSULIN-SECRETING CELLS; MALE; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84906921621     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077934     Document Type: Article

References (0)