Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle

Journal of Molecular and Cellular Cardiology

Volumn 57, Issue 1, 2013, Pages 96-105

  Brette, Fabien ^a   Blandin, Erick ^b,c,d   Simard, Christophe ^b,c,d   Guinamard, Romain ^b,c,d   Salle, Laurent ^b,c,d  

^a STANFORD UNIVERSITY   (United States)

^b NORMANDIE UNIVERSITÉ   (France)

^c UNIVERSITÉ DE CAEN   (France)

^d France   (France)

Author keywords

8 CPT AM; Action potential; Calcium current; Cardiac myocyte; Epac; Potassium current

Indexed keywords

CYCLIC AMP BINDING PROTEIN; POTASSIUM ION; PROTEIN EPAC; SODIUM ION; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM TRANSPORT; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART REPOLARIZATION; HEART VENTRICLE; HEART VENTRICLE HYPERTROPHY; ION CURRENT; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; UPREGULATION;

ACTION POTENTIALS; ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM SIGNALING; CARBAZOLES; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG EVALUATION, PRECLINICAL; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEART VENTRICLES; ISOPROTERENOL; MALE; MYOCYTES, CARDIAC; POTASSIUM; PYRROLES; RATS; RATS, WISTAR;

RATTUS;

EID: 84874088506     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.012     Document Type: Article

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