Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

Cell Reports

Volumn 11, Issue 10, 2015, Pages 1529-1534

  Solon Biet, Samantha M ^a   Mitchell, Sarah J ^b   Coogan, Sean C P ^a   Cogger, Victoria C ^a   Gokarn, Rahul ^a   McMahon, Aisling C ^a   Raubenheimer, David ^a   de Cabo, Rafael ^b   Simpson, Stephen J ^a   Le Couteur, David G ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LIPID; CARBOHYDRATE DIET; PROTEIN INTAKE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY MASS; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; DIET; ENERGY EXPENDITURE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HOMEOSTASIS; LOW PROTEIN HIGH CARBOHYDRATE DIET; LUNG GAS EXCHANGE; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; ADMINISTRATION AND DOSAGE; ANIMAL; C57BL MOUSE; CARBOHYDRATE DIET; COMPARATIVE STUDY; METABOLISM; PROTEIN INTAKE; RANDOMIZATION;

MUS;

ANIMALS; CALORIC RESTRICTION; DIETARY CARBOHYDRATES; DIETARY PROTEINS; ENERGY INTAKE; GLUCOSE; MALE; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION;

EID: 84937634400     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.05.007     Document Type: Article

References (37)

1. Ajala O., English P., Pinkney J. Systematic review and meta-analysis of different dietary approaches to the management of type 2 diabetes. Am. J. Clin. Nutr. 2013, 97:505-516.
2. Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
3. Cogger V.C., O'Reilly J., Warren A., Le Couteur D.G. A standardized method for the analysis of liver sinusoidal endothelial cells and their fenestrations by scanning electron microscopy. J. Vis. Exp. 2015, e52698. 10.3791/52698.
4. Dietrich P., Hellerbrand C. Non-alcoholic fatty liver disease, obesity and the metabolic syndrome. Best Pract. Res. Clin. Gastroenterol. 2014, 28:637-653.
5. Eisenstein A.B., Strack I., Steiner A. Glucagon stimulation of hepatic gluconeogenesis in rats fed a high-protein, carbohydrate-free diet. Metabolism 1974, 23:15-23.
6. Everitt A.V., Rattan S.I., Le Couteur D.G., de Cabo R. Calorie Restriction, Aging and Longevity 2010, Springer.
7. Fontana L., Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell 2015, 161:106-118.
8. Fontana L., Partridge L., Longo V.D. Extending healthy life span-from yeast to humans. Science 2010, 328:321-326.
9. Fung T.T., van Dam R.M., Hankinson S.E., Stampfer M., Willett W.C., Hu F.B. Low-carbohydrate diets and all-cause and cause-specific mortality: two cohort studies. Ann. Intern. Med. 2010, 153:289-298.
10. Gosby A.K., Conigrave A.D., Lau N.S., Iglesias M.A., Hall R.M., Jebb S.A., Brand-Miller J., Caterson I.D., Raubenheimer D., Simpson S.J. Testing protein leverage in lean humans: a randomised controlled experimental study. PLoS ONE 2011, 6:e25929.
11. Gosby A.K., Conigrave A.D., Raubenheimer D., Simpson S.J. Protein leverage and energy intake. Obes. Rev. 2014, 15:183-191.
12. Huang X., Hancock D.P., Gosby A.K., McMahon A.C., Solon S.M., Le Couteur D.G., Conigrave A.D., Raubenheimer D., Simpson S.J. Effects of dietary protein to carbohydrate balance on energy intake, fat storage, and heat production in mice. Obesity (Silver Spring) 2013, 21:85-92.
13. Lagiou P., Sandin S., Lof M., Trichopoulos D., Adami H.O., Weiderpass E. Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study. BMJ 2012, 344:e4026.
14. Le Couteur D.G., McLachlan A.J., Quinn R.J., Simpson S.J., de Cabo R. Aging biology and novel targets for drug discovery. J. Gerontol. A Biol. Sci. Med. Sci. 2012, 67:168-174.
15. Le Couteur D.G., Tay S.S., Solon-Biet S., Bertolino P., McMahon A.C., Cogger V.C., Colakoglu F., Warren A., Holmes A.J., Pichaud N., et al. The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice. J. Gerontol. A Biol. Sci. Med. Sci. 2014, Published online October 21, 2014. 10.1093/gerona/glu196.
16. Lee K.P., Simpson S.J., Clissold F.J., Brooks R., Ballard J.W., Taylor P.W., Soran N., Raubenheimer D. Lifespan and reproduction in Drosophila: New insights from nutritional geometry. Proc. Natl. Acad. Sci. USA 2008, 105:2498-2503.
17. Levine M.E., Suarez J.A., Brandhorst S., Balasubramanian P., Cheng C.W., Madia F., Fontana L., Mirisola M.G., Guevara-Aguirre J., Wan J., et al. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 2014, 19:407-417.
18. Linn T., Santosa B., Grönemeyer D., Aygen S., Scholz N., Busch M., Bretzel R.G. Effect of long-term dietary protein intake on glucose metabolism in humans. Diabetologia 2000, 43:1257-1265.
19. Maki K.C., Phillips A.K. Dietary substitutions for refined carbohydrate that show promise for reducing risk of type 2 diabetes in men and women. J. Nutr. 2015, 145:159S-163S.
20. Masoro E.J. Overview of caloric restriction and ageing. Mech. Ageing Dev. 2005, 126:913-922.
21. Mattison J.A., Roth G.S., Beasley T.M., Tilmont E.M., Handy A.M., Herbert R.L., Longo D.L., Allison D.B., Young J.E., Bryant M., et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 2012, 489:318-321.
22. McCay C., Crowell M., Maynard L. The effect of retarded growth upon the length of life and upon ultimate size. J. Nutr. 1935, 10:63-79.
23. Mercken E.M., Carboneau B.A., Krzysik-Walker S.M., de Cabo R. Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Ageing Res. Rev. 2012, 11:390-398.
24. Nseir W., Hellou E., Assy N. Role of diet and lifestyle changes in nonalcoholic fatty liver disease. World J. Gastroenterol. 2014, 20:9338-9344.
25. Piper M.D., Partridge L., Raubenheimer D., Simpson S.J. Dietary restriction and aging: a unifying perspective. Cell Metab. 2011, 14:154-160.
26. Raubenheimer D., Machovsky-Capuska G.E., Gosby A.K., Simpson S. Nutritional ecology of obesity: from humans to companion animals. Br. J. Nutr. 2015, 113:S26-S39.
27. Simpson S.J., Raubenheimer D. Obesity: the protein leverage hypothesis. Obes. Rev. 2005, 6:133-142.
28. Simpson S.J., Le Couteur D.G., Raubenheimer D. Putting the balance back in diet. Cell 2015, 161:18-23.
29. Solon-Biet S.M., McMahon A.C., Ballard J.W.O., Ruohonen K., Wu L.E., Cogger V.C., Warren A., Huang X., Pichaud N., Melvin R.G., et al. The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metab. 2014, 19:418-430.
30. Solon-Biet S.M., Walters K.A., Simanainen U.K., McMahon A.C., Ruohonen K., Ballard J.W.O., Raubenheimer D., Handelsman D.J., Le Couteur D.G., Simpson S.J. Macronutrient balance, reproductive function, and lifespan in aging mice. Proc. Natl. Acad. Sci. USA 2015, 112:3481-3486.
31. Sørensen A., Mayntz D., Raubenheimer D., Simpson S.J. Protein-leverage in mice: the geometry of macronutrient balancing and consequences for fat deposition. Obesity (Silver Spring) 2008, 16:566-571.
32. Stock M.J. Gluttony and thermogenesis revisited. Int. J. Obes. Relat. Metab. Disord. 1999, 23:1105-1117.
33. Storlien L.H., Kraegen E.W., Jenkins A.B., Chisholm D.J. Effects of sucrose vs starch diets on in vivo insulin action, thermogenesis, and obesity in rats. Am. J. Clin. Nutr. 1988, 47:420-427.
34. Thorburn A.W., Storlien L.H., Jenkins A.B., Khouri S., Kraegen E.W. Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am. J. Clin. Nutr. 1989, 49:1155-1163.
35. Thresher J.S., Podolin D.A., Wei Y., Mazzeo R.S., Pagliassotti M.J. Comparison of the effects of sucrose and fructose on insulin action and glucose tolerance. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 279:R1334-R1340.
36. Weindruch R., Walford R.L., Fligiel S., Guthrie D. The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J. Nutr. 1986, 116:641-654.
37. Wylie-Rosett J., Segal-Isaacson C.J., Segal-Isaacson A. Carbohydrates and increases in obesity: does the type of carbohydrate make a difference?. Obes. Res. 2004, 12(Suppl 2):124S-129S.