Advances in computationally modeling human oral bioavailability

Advanced Drug Delivery Reviews

Volumn 86, Issue , 2015, Pages 11-16

  Wang, Junmei ^a   Hou, Tingjun ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

ADME Tox; Human intestinal absorption (HIA); Human oral bioavailability (HOBA); In silico modeling computer aided drug design; QSAR

Indexed keywords

COMPUTATIONAL CHEMISTRY; DRUG PRODUCTS;

ADME-TOX; COMPUTER AIDED DRUG DESIGN; HUMAN INTESTINAL ABSORPTIONS; ORAL BIOAVAILABILITIES; QSAR;

BIOCHEMISTRY;

DRUG;

AREA UNDER THE CURVE; CLASSIFICATION; CLASSIFIER; COMPUTER MODEL; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG PENETRATION; DRUG SOLUBILITY; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SUPPORT VECTOR MACHINE; ANIMAL; BIOAVAILABILITY; BIOLOGICAL MODEL; COMPUTER SIMULATION; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; PHARMACOKINETICS;

EID: 84937630892     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2015.01.001     Document Type: Review

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