-
1
-
-
33645215637
-
Deaths: Injuries, 2002. National vital statistics reports: From the Centers for Disease Control and Prevention, National Center for Health Statistics
-
Minino AM, Anderson RN, Fingerhut LA, Boudreault MA, Warner M. (2006) Deaths: injuries, 2002. National vital statistics reports: from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System 54:1-124.
-
(2006)
National Vital Statistics System
, vol.54
, pp. 1-124
-
-
Minino, A.M.1
Erson, R.N.2
Fingerhut, L.A.3
Boudreault, M.A.4
Warner, M.5
-
2
-
-
70350029080
-
Resuscitation and transfusion principles for traumatic hemorrhagic shock
-
Spinella PC, Holcomb JB. (2009) Resuscitation and transfusion principles for traumatic hemorrhagic shock. Blood Rev. 23:231-40.
-
(2009)
Blood Rev
, vol.23
, pp. 231-240
-
-
Spinella, P.C.1
Holcomb, J.B.2
-
3
-
-
33745155396
-
Impact of hemorrhage on trauma outcome: An overview of epidemiology, clinical presentations, and therapeutic considerations
-
Kauvar DS, Lefering R, Wade CE. (2006) Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations. J. Trauma. 60:S3-11.
-
(2006)
J. Trauma
, vol.60
-
-
Kauvar, D.S.1
Lefering, R.2
Wade, C.E.3
-
4
-
-
79952337188
-
The acute management of trauma hemorrhage: A systematic review of randomized controlled trials
-
Curry N, et al. (2011) The acute management of trauma hemorrhage: a systematic review of randomized controlled trials. Crit. Care. 15:R92.
-
(2011)
Crit. Care
, vol.15
-
-
Curry, N.1
-
5
-
-
78751635896
-
Improved survival after hemostatic resuscitation: Does the emperor have no clothes
-
Magnotti LJ, et al. (2011) Improved survival after hemostatic resuscitation: does the emperor have no clothes? J. Trauma. 70:97-102.
-
(2011)
J. Trauma
, vol.70
, pp. 97-102
-
-
Magnotti, L.J.1
-
6
-
-
79955817385
-
State of the art of fluid resuscitation 2010: Prehospital and immediate transition to the hospital
-
McSwain NE, et al. (2011) State of the art of fluid resuscitation 2010: prehospital and immediate transition to the hospital. J. Trauma. 70:S2-10.
-
(2011)
J. Trauma
, vol.70
-
-
McSwain, N.E.1
-
7
-
-
84916940622
-
Aging and injury: Alterations in cellular energetics and organ function
-
Poulose N, Raju R. (2014) Aging and injury: alterations in cellular energetics and organ function. Aging Dis. 5:101-8.
-
(2014)
Aging Dis
, vol.5
, pp. 101-108
-
-
Poulose, N.1
Raju, R.2
-
8
-
-
41649112071
-
Estrogen: A novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations
-
Raju R, Bland KI, Chaudry IH. (2008) Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations. Mol. Med. 14:213-21.
-
(2008)
Mol. Med
, vol.14
, pp. 213-221
-
-
Raju, R.1
Bland, K.I.2
Chaudry, I.H.3
-
9
-
-
84873676655
-
Modulation of the unfolded protein response during hepatocyte and cardiomyocyte apoptosis in trauma/hemorrhagic shock
-
Thacker SA, Robinson P, Abel A, Tweardy DJ. (2013) Modulation of the unfolded protein response during hepatocyte and cardiomyocyte apoptosis in trauma/hemorrhagic shock. Sci. Rep. 3:1187.
-
(2013)
Sci. Rep
, vol.3
, pp. 1187
-
-
Thacker, S.A.1
Robinson, P.2
Abel, A.3
Tweardy, D.J.4
-
10
-
-
0031711449
-
Interleukin-6 production in hemorrhagic shock is accompanied by neutrophil recruitment and lung injury
-
Hierholzer C, et al. (1998) Interleukin-6 production in hemorrhagic shock is accompanied by neutrophil recruitment and lung injury. Am. J. Physiol. 275:L611-621.
-
(1998)
Am. J. Physiol
, vol.275
-
-
Hierholzer, C.1
-
11
-
-
84880264094
-
Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression
-
Villarroel JP, et al. (2013) Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression. J. Trauma Acute Care Surg. 75:24-31.
-
(2013)
J. Trauma Acute Care Surg
, vol.75
, pp. 24-31
-
-
Villarroel, J.P.1
-
12
-
-
84871861721
-
Oxidative modification of the intestinal mucus layer is a critical but unrecognized component of trauma hemorrhagic shock-induced gut barrier failure
-
Fishman JE, et al. (2013) Oxidative modification of the intestinal mucus layer is a critical but unrecognized component of trauma hemorrhagic shock-induced gut barrier failure. Am. J. Physiol. Gastrointest. Liver Physiol. 304: G57-63.
-
(2013)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.304
-
-
Fishman, J.E.1
-
13
-
-
73449108046
-
Trauma-hemorrhage and hypoxia differentially influence kupffer cell phagocytic capacity: Role of hypoxia-induciblefactor-1alpha and phosphoinositide 3-kinase/Akt activation
-
Hsieh CH, et al. (2009) Trauma-hemorrhage and hypoxia differentially influence kupffer cell phagocytic capacity: role of hypoxia-induciblefactor-1alpha and phosphoinositide 3-kinase/Akt activation. Ann. Surg. 250:995-1001.
-
(2009)
Ann. Surg
, vol.250
, pp. 995-1001
-
-
Hsieh, C.H.1
-
14
-
-
53449097985
-
Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apoptosis
-
Kan WH, et al. (2008) Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apoptosis. J. Appl. Physiol. (1985) 105:595-602.
-
(2008)
J. Appl. Physiol. (1985)
, vol.105
, pp. 595-602
-
-
Kan, W.H.1
-
15
-
-
84911954088
-
The role of intrinsic apoptotic signaling in hemorrhagic shock-induced microvascular endothelial cell barrier dysfunction
-
Sawant DA, Tharakan B, Hunter FA, Childs EW. (2014) The role of intrinsic apoptotic signaling in hemorrhagic shock-induced microvascular endothelial cell barrier dysfunction. J. Cardiovasc. Transl. Res. 7:711-18.
-
(2014)
J. Cardiovasc. Transl. Res
, vol.7
, pp. 711-718
-
-
Sawant, D.A.1
Tharakan, B.2
Hunter, F.A.3
Childs, E.W.4
-
16
-
-
84908670174
-
Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats
-
Escobales N, et al. (2014) Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats. J. Mol. Cell. Cardiol. 77:136-46.
-
(2014)
J. Mol. Cell. Cardiol
, vol.77
, pp. 136-146
-
-
Escobales, N.1
-
17
-
-
84901697863
-
Mitochondria in lung biology and pathology: More than just a powerhouse
-
Schumacker PT, et al. (2014) Mitochondria in lung biology and pathology: more than just a powerhouse. Am. J. Physiol. Lung Cell. Mol. Physiol. 306:L962-74.
-
(2014)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.306
-
-
Schumacker, P.T.1
-
18
-
-
84867417361
-
Bioenergetic origins of complexity and disease
-
Wallace DC. (2011) Bioenergetic origins of complexity and disease. Cold Spring Harb. Symp. Quant. Biol. 76:1-16.
-
(2011)
Cold Spring Harb. Symp. Quant. Biol
, vol.76
, pp. 1-16
-
-
Wallace, D.C.1
-
19
-
-
84894165975
-
Cardiac mitochondria and reactive oxygen species generation
-
Chen YR, Zweier JL. (2014) Cardiac mitochondria and reactive oxygen species generation. Circ. Res. 114:524-37.
-
(2014)
Circ. Res
, vol.114
, pp. 524-537
-
-
Chen, Y.R.1
Zweier, J.L.2
-
20
-
-
84928635872
-
Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via TGF-β/Smad3 pathway
-
Chen T, et al. (2014) Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via TGF-β/Smad3 pathway. Am. J. Physiol. Heart Circ. Physiol. 308:H424-34.
-
(2014)
Am. J. Physiol. Heart Circ. Physiol
, vol.308
-
-
Chen, T.1
-
22
-
-
84927137211
-
Resveratrol protects neurons and the myocardium by reducing oxidative stress and ameliorating mitochondria damage in a cerebral ischemia rat model
-
Wang R, et al. (2014) Resveratrol protects neurons and the myocardium by reducing oxidative stress and ameliorating mitochondria damage in a cerebral ischemia rat model. Cell. Physiol. Biochem. 34:854-64.
-
(2014)
Cell. Physiol. Biochem
, vol.34
, pp. 854-864
-
-
Wang, R.1
-
23
-
-
84859067589
-
Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1
-
Jian B, Yang S, Chaudry IH, Raju R. (2012) Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1. Mol. Med. 18:209-14.
-
(2012)
Mol. Med
, vol.18
, pp. 209-214
-
-
Jian, B.1
Yang, S.2
Chaudry, I.H.3
Raju, R.4
-
24
-
-
84918524934
-
Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock
-
Wang H, et al. (2014) Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock. J. Trauma Acute Care Surg. 77:926-933.
-
(2014)
J. Trauma Acute Care Surg
, vol.77
, pp. 926-933
-
-
Wang, H.1
-
25
-
-
84867239219
-
Attenuation of lung inflammation and pro-inflammatory cytokine production by resveratrol following trauma-hemorrhage
-
Wu CT, Yu HP, Chung CY, Lau YT, Liao SK. (2008) Attenuation of lung inflammation and pro-inflammatory cytokine production by resveratrol following trauma-hemorrhage. Chin. J. Physiol. 51:363-8.
-
(2008)
Chin. J. Physiol
, vol.51
, pp. 363-368
-
-
Wu, C.T.1
Yu, H.P.2
Chung, C.Y.3
Lau, Y.T.4
Liao, S.K.5
-
26
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, et al. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 444:337-42.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
-
27
-
-
84860477354
-
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
-
Price NL, et al. (2012) SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab. 15:675-90.
-
(2012)
Cell Metab
, vol.15
, pp. 675-690
-
-
Price, N.L.1
-
28
-
-
84897429184
-
Effect of resveratrol on mitochondrial function: Implications in parkinassociated familiar Parkinson’s disease
-
Ferretta A, et al. (2014) Effect of resveratrol on mitochondrial function: implications in parkinassociated familiar Parkinson’s disease. Biochim. Biophys. Acta. 1842:902-15.
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 902-915
-
-
Ferretta, A.1
-
29
-
-
84925871294
-
Mitochondrial biogenesis: Pharmacological approaches
-
Valero T. (2014) Mitochondrial biogenesis: pharmacological approaches. Curr. Pharm. Des. 20:5507-9.
-
(2014)
Curr. Pharm. Des
, vol.20
, pp. 5507-5509
-
-
Valero, T.1
-
30
-
-
84860825929
-
Role of Aktdependent pathway in resveratrol-mediated cardioprotection after trauma-hemorrhage
-
Tsai YF, Liu FC, Lau YT, Yu HP. (2012) Role of Aktdependent pathway in resveratrol-mediated cardioprotection after trauma-hemorrhage. J. Surg. Res. 176:171-7.
-
(2012)
J. Surg. Res
, vol.176
, pp. 171-177
-
-
Tsai, Y.F.1
Liu, F.C.2
Lau, Y.T.3
Yu, H.P.4
-
32
-
-
84863011114
-
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
-
Park SJ, et al. (2012) Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell. 148:421-33.
-
(2012)
Cell
, vol.148
, pp. 421-433
-
-
Park, S.J.1
-
33
-
-
84925503952
-
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol
-
Sajish M, Schimmel P. (2014) A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. Nature. 519:370-3.
-
(2014)
Nature
, vol.519
, pp. 370-373
-
-
Sajish, M.1
Schimmel, P.2
-
34
-
-
84861852370
-
Are sirtuins viable targets for improving healthspan and lifespan?
-
Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R. (2012) Are sirtuins viable targets for improving healthspan and lifespan? Nat. Rev. Drug Discov. 11:443-61.
-
(2012)
Nat. Rev. Drug Discov
, vol.11
, pp. 443-461
-
-
Baur, J.A.1
Ungvari, Z.2
Minor, R.K.3
Le Couteur, D.G.4
De Cabo, R.5
-
36
-
-
57049148639
-
Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage
-
Ba ZF, Chaudry IH. (2008) Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage. Am. J. Physiol. Heart. Circ. Physiol. 295:H2061-7.
-
(2008)
Am. J. Physiol. Heart. Circ. Physiol
, vol.295
-
-
Ba, Z.F.1
Chaudry, I.H.2
-
37
-
-
62449166297
-
The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage
-
Yu HP, Chaudry IH. (2009) The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage. Shock. 31:227-37.
-
(2009)
Shock
, vol.31
, pp. 227-237
-
-
Yu, H.P.1
Chaudry, I.H.2
-
38
-
-
84918836448
-
The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice
-
Gano LB, et al. (2014) The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. Am. J. Physiol. Heart. Circ. Physiol. 307:H1754-63.
-
(2014)
Am. J. Physiol. Heart. Circ. Physiol
, vol.307
-
-
Gano, L.B.1
-
39
-
-
84895925833
-
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
-
Mitchell SJ, et al. (2014) The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet. Cell Rep. 6:836-43.
-
(2014)
Cell Rep
, vol.6
, pp. 836-843
-
-
Mitchell, S.J.1
-
40
-
-
85017790529
-
Cardioprotection by estrogen related receptor (ERR)-beta and-gamma agonist DY131 after trauma-hemorrhage (T-H) is via DY131-derived restoration of cardiac sirtuins (SIRT) [Abstract]
-
Yang SH, et al. (2014) Cardioprotection by estrogen related receptor (ERR)-beta and-gamma agonist DY131 after trauma-hemorrhage (T-H) is via DY131-derived restoration of cardiac sirtuins (SIRT) [Abstract]. Shock. 41 Suppl 2:63-4.
-
(2014)
Shock
, vol.41
, pp. 63-64
-
-
Yang, S.H.1
-
41
-
-
0036850294
-
Early antioxidant therapy with Tempol during hemorrhagic shock increases survival in rats
-
Kentner R, et al. (2002) Early antioxidant therapy with Tempol during hemorrhagic shock increases survival in rats. J. Trauma. 53:968-77.
-
(2002)
J. Trauma
, vol.53
, pp. 968-977
-
-
Kentner, R.1
-
42
-
-
84858595301
-
Protecting mitochondrial bioenergetic function during resuscitation from cardiac arrest
-
Gazmuri RJ, Radhakrishnan J. (2012) Protecting mitochondrial bioenergetic function during resuscitation from cardiac arrest. Crit. Care Clin. 28:245-270.
-
(2012)
Crit. Care Clin
, vol.28
, pp. 245-270
-
-
Gazmuri, R.J.1
Radhakrishnan, J.2
-
43
-
-
77955984387
-
Pathophysiological roles of peroxynitrite in circulatory shock
-
Szabo C, Modis K. (2010) Pathophysiological roles of peroxynitrite in circulatory shock. Shock. 34 Suppl 1:4-14.
-
(2010)
Shock. 34 Suppl
, vol.1
, pp. 4-14
-
-
Szabo, C.1
Modis, K.2
-
44
-
-
84924168377
-
MitoQ modulates oxidative stress and decreases inflammation following hemorrhage
-
Powell RD, et al. (2015) MitoQ modulates oxidative stress and decreases inflammation following hemorrhage. J. Trauma Acute Care Surg. 78:573-9.
-
(2015)
J. Trauma Acute Care Surg
, vol.78
, pp. 573-579
-
-
Powell, R.D.1
-
45
-
-
85003474990
-
Ubiquinol decreases hemorrhagic shock/resuscitation-induced microvascular inflammation in rat mesenteric microcirculation
-
pii
-
Shen Q, et al. (2014) Ubiquinol decreases hemorrhagic shock/resuscitation-induced microvascular inflammation in rat mesenteric microcirculation. Physiol. Rep. 2.pii:e12199.
-
(2014)
Physiol. Rep
, vol.2
-
-
Shen, Q.1
-
46
-
-
84878525986
-
Oxidative stress in vascular disease and its pharmacological prevention
-
Li H, Horke S, Forstermann U. (2013) Oxidative stress in vascular disease and its pharmacological prevention. Trends Pharmacol. Sci. 34:313-9.
-
(2013)
Trends Pharmacol. Sci
, vol.34
, pp. 313-319
-
-
Li, H.1
Horke, S.2
Forstermann, U.3
-
47
-
-
9944248650
-
Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells
-
Juan SH, Cheng TH, Lin HC, Chu YL, Lee WS. (2005) Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells. Biochem. Pharmacol. 69:41-8.
-
(2005)
Biochem. Pharmacol
, vol.69
, pp. 41-48
-
-
Juan, S.H.1
Cheng, T.H.2
Lin, H.C.3
Chu, Y.L.4
Lee, W.S.5
-
48
-
-
84888855862
-
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases
-
Carrizzo A, et al. (2013) Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. Food Chem. Toxicol. 61:215-26.
-
(2013)
Food Chem. Toxicol
, vol.61
, pp. 215-226
-
-
Carrizzo, A.1
-
49
-
-
84904665699
-
Resveratrol: Review on therapeutic potential and recent advances in drug delivery
-
Pangeni R, Sahni JK, Ali J, Sharma S, Baboota S. (2014) Resveratrol: review on therapeutic potential and recent advances in drug delivery. Expert Opin. Drug Deliv. 11:1285-98.
-
(2014)
Expert Opin. Drug Deliv
, vol.11
, pp. 1285-1298
-
-
Pangeni, R.1
Sahni, J.K.2
Ali, J.3
Sharma, S.4
Baboota, S.5
|