Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression

Journal of Trauma and Acute Care Surgery

Volumn 75, Issue 1, 2013, Pages 24-31

  Villarroel, Jose Paul Perales ^a   Guan, Yuxia ^a   Werlin, Evan ^b   Selak, Mary A ^b   Becker, Lance B ^b   Sims, Carrie A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Hemorrhagic shock; Immune function; Long Evans rats; Mitochondrial function; Peripheral blood mononuclear cell; Rats

Indexed keywords

ADENOSINE TRIPHOSPHATE; ENDOTOXIN; INFUSION FLUID; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BREATHING; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FLOW CYTOMETRY; HEMORRHAGIC SHOCK; IMMUNOSUPPRESSIVE TREATMENT; LONG EVANS RAT; MALE; MEAN ARTERIAL PRESSURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA; PRIORITY JOURNAL; RAT; RESPIROMETRY; RESUSCITATION;

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOSUPPRESSION; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALE; MITOCHONDRIA; OXYGEN CONSUMPTION; RANDOM ALLOCATION; RATS; RATS, LONG-EVANS; REACTIVE OXYGEN SPECIES; RESUSCITATION; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SHOCK, HEMORRHAGIC; SURVIVAL RATE;

EID: 84880264094     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182988b1f     Document Type: Article

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