Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1

Molecular Medicine

Volumn 18, Issue 2, 2012, Pages 209-214

  Jian, Bixi ^a   Yang, Shaolong ^a   Chaudry, Irshad H ^a,b,c   Raju, Raghavan ^a,b,c  

^a Kentucky   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C; MYC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RESVERATROL; SIRTINOL; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; CYTOSOL; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE FUNCTION; INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; RESUSCITATION; SHAM PROCEDURE;

ANIMALS; BENZAMIDES; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMORRHAGE; MALE; MYOCARDIAL CONTRACTION; NAPHTHOLS; RATS; RATS, SPRAGUE-DAWLEY; SIRTUIN 1; STILBENES; WOUNDS AND INJURIES;

EID: 84859067589     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2011.00365     Document Type: Article

References (52)

1. Mizushima Y, et al. (2000). Estradiol administration after trauma-hemorrhage improves cardiovascular and hepatocellular functions in male animals. Ann. Surg. 232:673-9.
2. Yarlagadda S, et al. (2006). Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage. Neurocrit. Care. 5:102-7.
3. Sayeed MM, Zhu M, Maitra SR. (1989). Alterations in cellular calcium and magnesium during circulatory/septic shock. Magnesium. 8:179-89.
4. Ayala A, Ertel W, Chaudry IH. (1996). Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes. Shock. 5:79-90.
5. Ba ZF, et al. (2000). Alterations in tissue oxygen consumption and extraction after trauma and hemorrhagic shock. Crit. Care Med. 28:2837-42.
6. Bulger EM, Cuschieri J, Warner K, Maier RV. (2007). Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock. Ann. Surg. 245:635-41.
7. Dewar D, Moore FA, Moore EE, Balogh Z. (2009). Postinjury multiple organ failure. Injury. 40:912-8.
8. Raju R, Bland KI, Chaudry IH. (2008). Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations. Mol. Med. 14:213-21.
9. Rushing GD, Britt LD. (2008). Reperfusion injury after hemorrhage: a collective review. Ann. Surg. 247:929-37.
10. Spinella PC, Holcomb JB. (2009). Resuscitation and transfusion principles for traumatic hemorrhagic shock. Blood Rev. 23:231-40.
11. Ambrosio G, Flaherty JT. (1992). Effects of the superoxide radical scavenger superoxide dismutase, and of the hydroxyl radical scavenger mannitol, on reperfusion injury in isolated rabbit hearts. Cardiovasc. Drugs Ther. 6:623-32.
12. Chen Q, Lesnefsky EJ. (2006). Depletion of cardiolipin and cytochrome c during ischemia increases hydrogen peroxide production from the electron transport chain. Free Radic. Biol. Med. 40:976-82.
13. Childs EW, et al. (2002). In vivo visualization of reactive oxidants and leukocyte-endothelial adherence following hemorrhagic shock. Shock. 18:423-7.
14. Hsieh YC, et al. (2006) Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1. Am. J. Physiol. Heart Circ. Physiol. 290:H416-23.
15. Jian B, Yang, S, Chen Q, Chaudry I, Raju R. (2011) Influence of aging and hemorrhage injury on Sirt1 expression: possible role of myc-Sirt1 regulation in mitochondrial function. Biochim. Biophys. Acta.1812:1445-51.
16. Petrovski G, Gurusamy N, Das DK. (2011). Resveratrol in cardiovascular health and disease. Ann. N. Y. Acad. Sci. 1215:22-33.
17. Renaud S, de LM. (1992). Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet. 339:1523-6.
18. Koo SH, Montminy M. (2006). In vino veritas: a tale of two sirt1s? Cell. 127:1091-3.
19. Park SK, et al. (2009). Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants. Aging Cell. 8:484-95.
20. Csiszar A, et al. (2006). Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am. J. Physiol. Heart Circ. Physiol. 291:H1694-9.
21. Das S, et al. (2005). Coordinated induction of iNOS-VEGF-KDR-eNOS after resveratrol consumption: a potential mechanism for resveratrol preconditioning of the heart. Vascul. Pharmacol. 42:281-9.
22. Lekli I, et al. (2008). Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin. Am. J. Physiol. Heart Circ. Physiol. 294: H859-66.
23. Hao HD, He LR. (2004). Mechanisms of cardiovascular protection by resveratrol. J. Med. Food. 7:290-8.
24. Lagouge M, et al. (2006). Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 127:1109-22.
25. la-Morte D, et al. (2009). Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway. Neuroscience. 159:993-1002.
26. Lopez-Lluch G, Irusta PM, Navas P, de CR. (2008). Mitochondrial biogenesis and healthy aging. Exp. Gerontol. 43:813-9.
27. Pervaiz S, Holme AL. (2009). Resveratrol: its biologic targets and functional activity. Antioxid. Redox. Signal. 11:2851-97.
28. Vingtdeux V, et al. (2010). AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J. Biol. Chem. 285:9100-13.
29. Jian B, et al. (2011). Aging influences cardiac mitochondrial gene expression and cardiovascular function following hemorrhage injury. Mol. Med. 17(5-6):542-9.
30. Jian B, et al. (2008). Activation of endoplasmic reticulum stress response following traumahemorrhage. Biochim. Biophys. Acta. 1782:621-6.
31. Yuan J, Minter-Dykhouse K, Lou Z. (2009). A c-Myc-SIRT1 feedback loop regulates cell growth and transformation. J. Cell Biol. 185:203-11.
32. Ghanim H, et al. (2011). A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J. Clin. Endocrinol. Metab. 96:1409-14.
33. Alcain FJ, Villalba JM. (2009). Sirtuin activators. Expert Opin. Ther. Pat. 19:403-14.
34. Zingarelli B, et al. (2009). Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Crit. Care Med. 37:1978-87.
35. Hsieh YC, et al. (2006). Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage. J. Mol. Cell. Cardiol. 41:511-21.
36. Wang P, et al. (2010). Peroxisome proliferatoractivated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart. Circ. Res. 106:911-9.
37. Zou L, et al. (2009). Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. Am. J. Physiol. Heart Circ. Physiol. 296:H515-23.
38. Raju R, Jian B, Hubbard W, Chaudry I. (2011). The mitoscriptome in aging and disease. Aging Dis. 2:174-80.
39. Kan WH, et al. (2008). Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis. J. Appl. Physiol. 105:595-602.
40. Yang R, et al. (2006). Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol. Med. 12:105-14.
41. Meldrum DR, et al. (1997). Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart. J. Mol. Cell. Cardiol. 29:2849-54.
42. Singh UP, et al. (2010). Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis. J. Pharmacol. Exp. Ther. 332:829-39.
43. Yu HP, Yang SC, Lau YT, Hwang TL. (2010). Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. Surgery. 148:103-9.
44. Picard F, et al. (2004). Sirt1 promotes fat mobilization in white adipocytes by repressing PPARgamma. Nature. 429:771-6.
45. Pruitt K, et al. (2006). Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2:e40.
46. Finkel T, Deng CX, Mostoslavsky R. (2009). Recent progress in the biology and physiology of sirtuins. Nature. 460:587-91.
47. Wang C, et al. (2006). Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat. Cell. Biol. 8:1025-31.
48. Lindstrom MS, Wiman KG. (2003). Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts. Oncogene. 22:4993-5005.
49. Anekonda TS, Reddy PH. (2006). Neuronal protection by sirtuins in Alzheimer's disease. J. Neurochem. 96:305-13.
50. Voelter-Mahlknecht S, Mahlknecht U. (2006). Cloning, chromosomal characterization and mapping of the NAD-dependent histone deacetylases gene sirtuin 1. Int. J. Mol. Med. 17:59-67.
51. Ahuja P, et al. (2010). Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J. Clin. Invest. 120:1494-505.
52. Wang C, Tai Y, Lisanti MP, Liao DJ. (2011). c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis. Cancer Biol. Ther. 11:615-26.