Large-scale qualitative and quantitative characterization of components in Shenfu injection by integrating hydrophilic interaction chromatography, reversed phase liquid chromatography, and tandem mass spectrometry

Journal of Chromatography A

Volumn 1407, Issue , 2015, Pages 106-118

  Song, Yuelin ^a   Zhang, Na ^a,b   Shi, Shepo ^a   Li, Jun ^a   Zhang, Qian ^a   Zhao, Yunfang ^a   Jiang, Yong ^c   Tu, Pengfei ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b BAOTOU MEDICAL COLLEGE   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Column switching hydrophilic interaction reversed phase liquid chromatography; Hydrophilic components; Hydrophobic compounds; Predefined multiple reaction monitoring; Shenfu injection

Indexed keywords

ALKALOIDS; AMINO ACIDS; BIOMOLECULES; COLUMN CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; IONS; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; MEDICINE; QUALITY CONTROL;

HYBRID TRIPLE QUADRUPOLE-LINEAR ION TRAP MASS SPECTROMETER; HYDROPHILIC COMPONENTS; HYDROPHILIC INTERACTION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; HYDROPHOBIC COMPOUNDS; MULTIPLE REACTION MONITORING; REVERSED PHASE LIQUID-CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

4 AMINOBUTYRIC ACID; ADENINE; ADENOSINE; ALANINE; ALKALOID DERIVATIVE; BENZOYLACONINE; BENZOYLHYPACONINE; BENZOYLMESACONINE; CHINESE DRUG; CYSTEINE; CYTIDINE; CYTOSINE; GINSENOSIDE; GLUTAMINE; GUANINE; GUANOSINE; HYPACONITINE; INOSINE; ISOLEUCINE; MESACONITINE; PHENYLALANINE; PROLINE; SHENFU; SONGORINE; THREONINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; URACIL; URIDINE; ALKALOID; HERBACEOUS AGENT; NUCLEOSIDE; SHEN-FU;

ARTICLE; BIOCHEMICAL COMPOSITION; CHINESE MEDICINE; DRUG ANALYSIS; DRUG QUALITY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; ION MONITORING; ION TRAP MASS SPECTROMETRY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; VALIDATION STUDY; CHEMICAL ANALYSIS; CHEMICAL PHENOMENA; CHEMISTRY; DEVICES; PROCEDURES; STANDARDS;

ACONITUM;

ALKALOIDS; CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY, REVERSE-PHASE; DRUGS, CHINESE HERBAL; GINSENOSIDES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NUCLEOSIDES; TANDEM MASS SPECTROMETRY;

EID: 84937522649     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.06.041     Document Type: Article

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