Sesamol suppresses the inflammatory response by inhibiting NF-κB/MAPK activation and upregulating AMP kinase signaling in RAW 264.7 macrophages

Inflammation Research

Volumn 64, Issue 8, 2015, Pages 577-588

  Wu, Xin Ling ^a   Liou, Chian Jiun ^a   Li, Zih Ying ^a   Lai, Xuan Yu ^a   Fang, Li Wen ^b   Huang, Wen Chung ^a  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

Author keywords

AMPK; COX 2; HO 1; MAPK; NF B; Sesamol

Indexed keywords

ADENYLATE KINASE; BETA ACTIN; CYCLOOXYGENASE 2; CYTOKINE; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LAMIN B; LAMIN B1; LIGNAN DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; SESAMOL; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 1,3 BENZODIOXOLE DERIVATIVE; ANTIINFLAMMATORY AGENT; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; PHENOL DERIVATIVE; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; INFLAMMATION; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

ADENYLATE KINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZODIOXOLES; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; HEME OXYGENASE-1; MACROPHAGES; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84937515880     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-015-0836-7     Document Type: Article

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