Astragalus polysaccharide attenuates lipopolysaccharide-induced inflammatory responses in microglial cells: regulation of protein kinase B and nuclear factor-κB signaling

Inflammation Research

Volumn 64, Issue 3-4, 2015, Pages 205-212

  Luo, Tao ^a   Qin, Jian ^b   Liu, Min ^b   Luo, Jun ^c   Ding, Fang ^a,d   Wang, Mingling ^a   Zheng, Limin ^a  

^a PEKING UNIVERSITY SHENZHEN HOSPITAL   (China)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^d ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Astragalus polysaccharide; Lipopolysaccharide; Microglia; Neuroinflammation

Indexed keywords

ANTIINFLAMMATORY AGENT; ASTRAGALUS EXTRACT; ASTRAGALUS POLYSACCHARIDE; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; POLYSACCHARIDE; PROSTAGLANDIN E; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PROSTAGLANDIN E2; PTGS2 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTRAGALUS MEMBRANACEUS; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE TRANSLOCATION; INFLAMMATION; INTRACELLULAR SIGNALING; MICROGLIA; MOUSE; NEWBORN; NONHUMAN; PROTEIN DEGRADATION; ANIMAL; ANIMAL MODEL; ASTRAGALUS (PLANT); CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ASTRAGALUS PLANT; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; INFLAMMATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MODELS, ANIMAL; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84925533821     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-015-0798-9     Document Type: Article

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