메뉴 건너뛰기




Volumn 12, Issue 3, 2015, Pages 462-473

Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 5; DYNEIN ADENOSINE TRIPHOSPHATASE; LIS1 PROTEIN; NDEL1 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; 1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; CARRIER PROTEIN; CDK5 PROTEIN, HUMAN; CDK5 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NDEL1 PROTEIN, HUMAN; NDEL1 PROTEIN, MOUSE; PAFAH1B1 PROTEIN, HUMAN; PAFAH1B1 PROTEIN, MOUSE;

EID: 84937513345     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.06.032     Document Type: Article
Times cited : (57)

References (44)
  • 3
    • 84888073509 scopus 로고    scopus 로고
    • NDE1 and NDEL1: twinneurodevelopmental proteins with similar 'nature' but different 'nurture'
    • Bradshaw N.J., Hennah W., Soares D.C. NDE1 and NDEL1: twinneurodevelopmental proteins with similar 'nature' but different 'nurture'. Biomol Concepts 2013, 4:447-464.
    • (2013) Biomol Concepts , vol.4 , pp. 447-464
    • Bradshaw, N.J.1    Hennah, W.2    Soares, D.C.3
  • 4
    • 84865654196 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention
    • Cozzolino M., Pesaresi M.G., Gerbino V., Grosskreutz J., Carrì M.T. Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention. Antioxid. Redox Signal. 2012, 17:1277-1330.
    • (2012) Antioxid. Redox Signal. , vol.17 , pp. 1277-1330
    • Cozzolino, M.1    Pesaresi, M.G.2    Gerbino, V.3    Grosskreutz, J.4    Carrì, M.T.5
  • 7
    • 84908488959 scopus 로고    scopus 로고
    • Integrated regulation of motor-driven organelle transport by scaffolding proteins
    • Fu M.M., Holzbaur E.L.F. Integrated regulation of motor-driven organelle transport by scaffolding proteins. Trends Cell Biol. 2014, 24:564-574.
    • (2014) Trends Cell Biol. , vol.24 , pp. 564-574
    • Fu, M.M.1    Holzbaur, E.L.F.2
  • 8
    • 84862253302 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons
    • Goodwin P.R., Sasaki J.M., Juo P. Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. J.Neurosci. 2012, 32:8158-8172.
    • (2012) J.Neurosci. , vol.32 , pp. 8158-8172
    • Goodwin, P.R.1    Sasaki, J.M.2    Juo, P.3
  • 9
    • 0344011447 scopus 로고    scopus 로고
    • Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice
    • Hallows J.L., Chen K., DePinho R.A., Vincent I. Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice. J.Neurosci. 2003, 23:10633-10644.
    • (2003) J.Neurosci. , vol.23 , pp. 10633-10644
    • Hallows, J.L.1    Chen, K.2    DePinho, R.A.3    Vincent, I.4
  • 10
    • 84906933847 scopus 로고    scopus 로고
    • Bidirectional cargo transport: moving beyond tug of war
    • Hancock W.O. Bidirectional cargo transport: moving beyond tug of war. Nat. Rev. Mol. Cell Biol. 2014, 15:615-628.
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , pp. 615-628
    • Hancock, W.O.1
  • 11
    • 52249097215 scopus 로고    scopus 로고
    • Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
    • Hebbar S., Mesngon M.T., Guillotte A.M., Desai B., Ayala R., Smith D.S. Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. J.Cell Biol. 2008, 182:1063-1071.
    • (2008) J.Cell Biol. , vol.182 , pp. 1063-1071
    • Hebbar, S.1    Mesngon, M.T.2    Guillotte, A.M.3    Desai, B.4    Ayala, R.5    Smith, D.S.6
  • 12
    • 78649723621 scopus 로고    scopus 로고
    • Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?
    • Henriques A., Pitzer C., Schneider A. Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?. Front Neurosci 2010, 4:32.
    • (2010) Front Neurosci , vol.4 , pp. 32
    • Henriques, A.1    Pitzer, C.2    Schneider, A.3
  • 13
    • 84865679752 scopus 로고    scopus 로고
    • Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor
    • Huang J., Roberts A.J., Leschziner A.E., Reck-Peterson S.L. Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor. Cell 2012, 150:975-986.
    • (2012) Cell , vol.150 , pp. 975-986
    • Huang, J.1    Roberts, A.J.2    Leschziner, A.E.3    Reck-Peterson, S.L.4
  • 14
    • 84857788913 scopus 로고    scopus 로고
    • Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    • Kiyomitsu T., Cheeseman I.M. Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation. Nat. Cell Biol. 2012, 14:311-317.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 311-317
    • Kiyomitsu, T.1    Cheeseman, I.M.2
  • 16
    • 0034595834 scopus 로고    scopus 로고
    • Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
    • Kusakawa G., Saito T., Onuki R., Ishiguro K., Kishimoto T., Hisanaga S. Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J.Biol. Chem. 2000, 275:17166-17172.
    • (2000) J.Biol. Chem. , vol.275 , pp. 17166-17172
    • Kusakawa, G.1    Saito, T.2    Onuki, R.3    Ishiguro, K.4    Kishimoto, T.5    Hisanaga, S.6
  • 17
    • 84857858536 scopus 로고    scopus 로고
    • Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
    • Maday S., Wallace K.E., Holzbaur E.L.F. Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J.Cell Biol. 2012, 196:407-417.
    • (2012) J.Cell Biol. , vol.196 , pp. 407-417
    • Maday, S.1    Wallace, K.E.2    Holzbaur, E.L.F.3
  • 18
    • 84908246114 scopus 로고    scopus 로고
    • Axonal transport: cargo-specific mechanisms of motility and regulation
    • Maday S., Twelvetrees A.E., Moughamian A.J., Holzbaur E.L.F. Axonal transport: cargo-specific mechanisms of motility and regulation. Neuron 2014, 84:292-309.
    • (2014) Neuron , vol.84 , pp. 292-309
    • Maday, S.1    Twelvetrees, A.E.2    Moughamian, A.J.3    Holzbaur, E.L.F.4
  • 19
    • 84894387057 scopus 로고    scopus 로고
    • Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models
    • Magrané J., Cortez C., Gan W.B., Manfredi G. Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models. Hum. Mol. Genet. 2014, 23:1413-1424.
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 1413-1424
    • Magrané, J.1    Cortez, C.2    Gan, W.B.3    Manfredi, G.4
  • 20
    • 77951701022 scopus 로고    scopus 로고
    • LIS1 and NudE induce a persistent dynein force-producing state
    • McKenney R.J., Vershinin M., Kunwar A., Vallee R.B., Gross S.P. LIS1 and NudE induce a persistent dynein force-producing state. Cell 2010, 141:304-314.
    • (2010) Cell , vol.141 , pp. 304-314
    • McKenney, R.J.1    Vershinin, M.2    Kunwar, A.3    Vallee, R.B.4    Gross, S.P.5
  • 21
  • 22
    • 77957860649 scopus 로고    scopus 로고
    • Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits invivo CDK5 activity increase in animal stroke models
    • Menn B., Bach S., Blevins T.L., Campbell M., Meijer L., Timsit S. Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits invivo CDK5 activity increase in animal stroke models. PLoS ONE 2010, 5:e12117.
    • (2010) PLoS ONE , vol.5 , pp. e12117
    • Menn, B.1    Bach, S.2    Blevins, T.L.3    Campbell, M.4    Meijer, L.5    Timsit, S.6
  • 25
    • 84866385935 scopus 로고    scopus 로고
    • Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons
    • Modi P.K., Komaravelli N., Singh N., Sharma P. Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons. Mol. Biol. Cell 2012, 23:3722-3730.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 3722-3730
    • Modi, P.K.1    Komaravelli, N.2    Singh, N.3    Sharma, P.4
  • 26
    • 77952548853 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta and the p25 activator of cyclin dependent kinase 5 increase pausing of mitochondria in neurons
    • Morel M., Authelet M., Dedecker R., Brion J.P. Glycogen synthase kinase-3beta and the p25 activator of cyclin dependent kinase 5 increase pausing of mitochondria in neurons. Neuroscience 2010, 167:1044-1056.
    • (2010) Neuroscience , vol.167 , pp. 1044-1056
    • Morel, M.1    Authelet, M.2    Dedecker, R.3    Brion, J.P.4
  • 27
    • 3042634127 scopus 로고    scopus 로고
    • A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons
    • Morfini G., Szebenyi G., Brown H., Pant H.C., Pigino G., DeBoer S., Beffert U., Brady S.T. A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J. 2004, 23:2235-2245.
    • (2004) EMBO J. , vol.23 , pp. 2235-2245
    • Morfini, G.1    Szebenyi, G.2    Brown, H.3    Pant, H.C.4    Pigino, G.5    DeBoer, S.6    Beffert, U.7    Brady, S.T.8
  • 28
    • 84860272533 scopus 로고    scopus 로고
    • Dynactin is required for transport initiation from the distal axon
    • Moughamian A.J., Holzbaur E.L.F. Dynactin is required for transport initiation from the distal axon. Neuron 2012, 74:331-343.
    • (2012) Neuron , vol.74 , pp. 331-343
    • Moughamian, A.J.1    Holzbaur, E.L.F.2
  • 29
    • 84881159743 scopus 로고    scopus 로고
    • Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport
    • Moughamian A.J., Osborn G.E., Lazarus J.E., Maday S., Holzbaur E.L.F. Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. J.Neurosci. 2013, 33:13190-13203.
    • (2013) J.Neurosci. , vol.33 , pp. 13190-13203
    • Moughamian, A.J.1    Osborn, G.E.2    Lazarus, J.E.3    Maday, S.4    Holzbaur, E.L.F.5
  • 30
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions
    • Nguyen M.D., Larivière R.C., Julien J.P. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 2001, 30:135-147.
    • (2001) Neuron , vol.30 , pp. 135-147
    • Nguyen, M.D.1    Larivière, R.C.2    Julien, J.P.3
  • 32
    • 0029966469 scopus 로고    scopus 로고
    • Thecdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
    • Nikolic M., Dudek H., Kwon Y.T., Ramos Y.F., Tsai L.H. Thecdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 1996, 10:816-825.
    • (1996) Genes Dev. , vol.10 , pp. 816-825
    • Nikolic, M.1    Dudek, H.2    Kwon, Y.T.3    Ramos, Y.F.4    Tsai, L.H.5
  • 34
    • 81855184645 scopus 로고    scopus 로고
    • A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons
    • Pandey J.P., Smith D.S. A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons. J.Neurosci. 2011, 31:17207-17219.
    • (2011) J.Neurosci. , vol.31 , pp. 17207-17219
    • Pandey, J.P.1    Smith, D.S.2
  • 35
    • 0032508698 scopus 로고    scopus 로고
    • P35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway
    • Patrick G.N., Zhou P., Kwon Y.T., Howley P.M., Tsai L.-H. p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. J.Biol. Chem. 1998, 273:24057-24064.
    • (1998) J.Biol. Chem. , vol.273 , pp. 24057-24064
    • Patrick, G.N.1    Zhou, P.2    Kwon, Y.T.3    Howley, P.M.4    Tsai, L.-H.5
  • 37
    • 77951207269 scopus 로고    scopus 로고
    • Motor number controls cargo switching at actin-microtubule intersections invitro
    • Schroeder H.W., Mitchell C., Shuman H., Holzbaur E.L.F., Goldman Y.E. Motor number controls cargo switching at actin-microtubule intersections invitro. Curr. Biol. 2010, 20:687-696.
    • (2010) Curr. Biol. , vol.20 , pp. 687-696
    • Schroeder, H.W.1    Mitchell, C.2    Shuman, H.3    Holzbaur, E.L.F.4    Goldman, Y.E.5
  • 38
    • 84871649258 scopus 로고    scopus 로고
    • Deregulated Cdk5 activity is involved in inducing Alzheimer's disease
    • Shukla V., Skuntz S., Pant H.C. Deregulated Cdk5 activity is involved in inducing Alzheimer's disease. Arch. Med. Res. 2012, 43:655-662.
    • (2012) Arch. Med. Res. , vol.43 , pp. 655-662
    • Shukla, V.1    Skuntz, S.2    Pant, H.C.3
  • 39
    • 80054045373 scopus 로고    scopus 로고
    • Cyclin-dependent kinases in brain development and disease
    • Su S.C., Tsai L.-H. Cyclin-dependent kinases in brain development and disease. Annu. Rev. Cell Dev. Biol. 2011, 27:465-491.
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27 , pp. 465-491
    • Su, S.C.1    Tsai, L.-H.2
  • 40
    • 0027425599 scopus 로고
    • Activity andexpression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
    • Tsai L.H., Takahashi T., Caviness V.S., Harlow E. Activity andexpression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development 1993, 119:1029-1040.
    • (1993) Development , vol.119 , pp. 1029-1040
    • Tsai, L.H.1    Takahashi, T.2    Caviness, V.S.3    Harlow, E.4
  • 41
    • 34548565750 scopus 로고    scopus 로고
    • Lissencephaly and LIS1: insights into the molecularmechanisms of neuronal migration and development
    • Wynshaw-Boris A. Lissencephaly and LIS1: insights into the molecularmechanisms of neuronal migration and development. Clin. Genet. 2007, 72:296-304.
    • (2007) Clin. Genet. , vol.72 , pp. 296-304
    • Wynshaw-Boris, A.1
  • 42
    • 84870594338 scopus 로고    scopus 로고
    • P10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity
    • Zhang L., Liu W., Szumlinski K.K., Lew J. p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity. Proc. Natl. Acad. Sci. USA 2012, 109:20041-20046.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 20041-20046
    • Zhang, L.1    Liu, W.2    Szumlinski, K.K.3    Lew, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.