-
2
-
-
0026345013
-
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein
-
Gill, S. R. et al. Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J. Cell Biol. 115, 1639-1650 (1991).
-
(1991)
J. Cell Biol.
, vol.115
, pp. 1639-1650
-
-
Gill, S.R.1
-
3
-
-
0028304474
-
Ultrastructural analysis of the dynactin complex: An actin-related protein is a component of a filament that resembles F-actin
-
Schafer, D. A., Gill, S. R., Cooper, J. A., Heuser, J. E. & Schroer, T. A. Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J. Cell Biol. 126, 403-412 (1994).
-
(1994)
J. Cell Biol.
, vol.126
, pp. 403-412
-
-
Schafer, D.A.1
Gill, S.R.2
Cooper, J.A.3
Heuser, J.E.4
Schroer, T.A.5
-
4
-
-
0025891138
-
Homology of a 150 K cytoplasmic dynein- associated polypeptide with the Drosophila gene Glued
-
Holzbaur, E. L. F. et al. Homology of a 150 K cytoplasmic dynein- associated polypeptide with the Drosophila gene Glued. Nature 351, 579-583 (1991).
-
(1991)
Nature
, vol.351
, pp. 579-583
-
-
Holzbaur, E.L.F.1
-
5
-
-
0028806377
-
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
-
Karki, S. & Holzbaur, E. L. F. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J. Biol. Chem. 270, 28806-28811 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28806-28811
-
-
Karki, S.1
Holzbaur, E.L.F.2
-
7
-
-
0028986631
-
Gluedcomponent of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)
-
Gluedcomponent of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proc. Natl Acad. Sci. USA 92, 1634-1638 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1634-1638
-
-
Waterman-Storer, C.M.1
Karki, S.2
Holzbaur, E.L.3
-
8
-
-
33644747344
-
A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules
-
Culver-Hanlon, T. L., Lex, S. A., Stephens, A. D., Quintyne, N. J. & King, S. J. A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules. Nat. Cell Biol. 8, 264-270 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 264-270
-
-
Culver-Hanlon, T.L.1
Lex, S.A.2
Stephens, A.D.3
Quintyne, N.J.4
King, S.J.5
-
10
-
-
0033789351
-
Dynactin increases the processivity of the cytoplasmic dynein motor
-
King, S. J. & Schroer, T. A. Dynactin increases the processivity of the cytoplasmic dynein motor. Nat. Cell Biol. 2, 20-24 (2000).
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 20-24
-
-
King, S.J.1
Schroer, T.A.2
-
11
-
-
84886750648
-
Teamwork in microtubule motors
-
Mallik, R., Rai, A. K., Barak, P., Rai, A. & Kunwar, A. Teamwork in microtubule motors. Trends Cell Biol. 23, 575-582 (2013).
-
(2013)
Trends Cell Biol.
, vol.23
, pp. 575-582
-
-
Mallik, R.1
Rai, A.K.2
Barak, P.3
Rai, A.4
Kunwar, A.5
-
12
-
-
65249170094
-
Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin
-
Kardon, J. R., Reck-Peterson, S. L. & Vale, R. D. Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proc. Natl Acad. Sci. USA 106, 5669-5674 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5669-5674
-
-
Kardon, J.R.1
Reck-Peterson, S.L.2
Vale, R.D.3
-
13
-
-
65249126818
-
Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration
-
Moore, J. K., Sept, D. & Cooper, J. A. Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration. Proc. Natl Acad. Sci. USA 106, 5147-5152 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5147-5152
-
-
Moore, J.K.1
Sept, D.2
Cooper, J.A.3
-
14
-
-
33847343375
-
Microtubule binding by dynactin is required for microtubule organization but not cargo transport
-
Kim, H. et al. Microtubule binding by dynactin is required for microtubule organization but not cargo transport. J. Cell Biol. 176, 641-651 (2007).
-
(2007)
J. Cell Biol.
, vol.176
, pp. 641-651
-
-
Kim, H.1
-
15
-
-
57749110732
-
Regulation of dynactin through the differential expression of p150 Glued isoforms
-
Dixit, R., Levy, J. R., Tokito, M., Ligon, L. A. & Holzbaur, E. L. F. Regulation of dynactin through the differential expression of p150 Glued isoforms. J. Biol. Chem. 283, 33611-33619 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33611-33619
-
-
Dixit, R.1
Levy, J.R.2
Tokito, M.3
Ligon, L.A.4
Holzbaur, E.L.F.5
-
16
-
-
84860303904
-
Glued CAP-Gly domain regulates initiation of retrograde transport at synaptic termini
-
Glued CAP-Gly domain regulates initiation of retrograde transport at synaptic termini. Neuron 74, 344-360 (2012).
-
(2012)
Neuron
, vol.74
, pp. 344-360
-
-
Lloyd, T.E.1
-
17
-
-
84860272533
-
Dynactin is required for transport initiation from the distal axon
-
Moughamian, A. J. & Holzbaur, E. L. F. Dynactin is required for transport initiation from the distal axon. Neuron 74, 331-343 (2012).
-
(2012)
Neuron
, vol.74
, pp. 331-343
-
-
Moughamian, A.J.1
Holzbaur, E.L.F.2
-
18
-
-
84881159743
-
Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport
-
Moughamian, A. J., Osborn, G. E., Lazarus, J. E., Maday, S. & Holzbaur, E. L. F. Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. J. Neurosci. 33, 13190-13203 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 13190-13203
-
-
Moughamian, A.J.1
Osborn, G.E.2
Lazarus, J.E.3
Maday, S.4
Holzbaur, E.L.F.5
-
19
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
Puls, I. et al. Mutant dynactin in motor neuron disease. Nat. Genet. 33, 455-456 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 455-456
-
-
Puls, I.1
-
20
-
-
59149097039
-
DCTN1 mutations in Perry syndrome
-
Farrer, M. J. et al. DCTN1 mutations in Perry syndrome. Nat. Genet. 41, 163-165 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 163-165
-
-
Farrer, M.J.1
-
21
-
-
33644551565
-
Gluedperturbs dynactin function and induces protein aggregation
-
Gluedperturbs dynactin function and induces protein aggregation. J. Cell Biol. 172, 733-745 (2006).
-
(2006)
J. Cell Biol.
, vol.172
, pp. 733-745
-
-
Levy, J.R.1
-
22
-
-
84876312705
-
Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions
-
Zhang, J. et al. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken) 70, 215-227 (2013).
-
(2013)
Cytoskeleton (Hoboken)
, vol.70
, pp. 215-227
-
-
Zhang, J.1
-
23
-
-
33744826279
-
Processive bidirectional motion of dynein-dynactin complexes in vitro
-
Ross, J. L., Wallace, K., Shuman, H., Goldman, Y. E. & Holzbaur, E. L. F. Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat. Cell Biol. 8, 562-570 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 562-570
-
-
Ross, J.L.1
Wallace, K.2
Shuman, H.3
Goldman, Y.E.4
Holzbaur, E.L.F.5
-
24
-
-
28444456051
-
Building complexity: An in vitro study of cytoplasmic dynein with in vivo implications
-
Mallik, R., Petrov, D., Lex, S. A., King, S. J. & Gross, S. P. Building complexity: an in vitro study of cytoplasmic dynein with in vivo implications. Curr. Biol. 15, 2075-2085 (2005).
-
(2005)
Curr. Biol.
, vol.15
, pp. 2075-2085
-
-
Mallik, R.1
Petrov, D.2
Lex, S.A.3
King, S.J.4
Gross, S.P.5
-
25
-
-
84872506411
-
Molecular adaptations allow dynein to generate large collective forces inside cells
-
Rai, A. K., Rai, A., Ramaiya, A. J., Jha, R. & Mallik, R. Molecular adaptations allow dynein to generate large collective forces inside cells. Cell 152, 172-182 (2013).
-
(2013)
Cell
, vol.152
, pp. 172-182
-
-
Rai, A.K.1
Rai, A.2
Ramaiya, A.J.3
Jha, R.4
Mallik, R.5
-
26
-
-
84868559187
-
Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors
-
Hendricks, A. G., Holzbaur, E. L. F. & Goldman, Y. E. Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc. Natl Acad. Sci. USA 109, 18447-18452 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 18447-18452
-
-
Hendricks, A.G.1
Holzbaur, E.L.F.2
Goldman, Y.E.3
-
27
-
-
84875923534
-
Dynein and dynactin leverage their bivalent character to form a high-affinity interaction
-
Siglin, A. E. et al. Dynein and dynactin leverage their bivalent character to form a high-affinity interaction. PLoS ONE 8, e59453 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e59453
-
-
Siglin, A.E.1
-
28
-
-
84865679752
-
Lis1 Acts as a "Clutch" between the ATPase and microtubule-binding domains of the dynein motor
-
Huang, J., Roberts, A. J., Leschziner, A. E. & Reck-peterson, S. L. Lis1 Acts as a "Clutch" between the ATPase and microtubule-binding domains of the dynein motor. Cell 150, 975-986 (2012).
-
(2012)
Cell
, vol.150
, pp. 975-986
-
-
Huang, J.1
Roberts, A.J.2
Leschziner, A.E.3
Reck-peterson, S.L.4
-
29
-
-
33845967100
-
Two binding partners cooperate to activate the molecular motor Kinesin-1
-
Blasius, T. L., Cai, D., Jih, G. T., Toret, C. P. & Verhey, K. J. Two binding partners cooperate to activate the molecular motor Kinesin-1. J. Cell Biol. 176, 11-17 (2007).
-
(2007)
J. Cell Biol.
, vol.176
, pp. 11-17
-
-
Blasius, T.L.1
Cai, D.2
Jih, G.T.3
Toret, C.P.4
Verhey, K.J.5
-
30
-
-
80155174991
-
Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility
-
Sun, F., Zhu, C., Dixit, R. & Cavalli, V. Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO J. 30, 3416-3429 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 3416-3429
-
-
Sun, F.1
Zhu, C.2
Dixit, R.3
Cavalli, V.4
-
31
-
-
84881189138
-
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
-
Fu, M. & Holzbaur, E. L. F. JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J. Cell Biol. 202, 495-508 (2013).
-
(2013)
J. Cell Biol.
, vol.202
, pp. 495-508
-
-
Fu, M.1
Holzbaur, E.L.F.2
-
32
-
-
84862531800
-
Evolution of the eukaryotic dynactin complex, the activator of cytoplasmic dynein
-
Hammesfahr, B. & Kollmar, M. Evolution of the eukaryotic dynactin complex, the activator of cytoplasmic dynein. BMC Evol. Biol. 12, 95 (2012).
-
(2012)
BMC Evol. Biol.
, vol.12
, pp. 95
-
-
Hammesfahr, B.1
Kollmar, M.2
-
33
-
-
33746253688
-
Single-molecule analysis of dynein processivity and stepping behavior
-
Reck-Peterson, S. L. et al. Single-molecule analysis of dynein processivity and stepping behavior. Cell 126, 335-348 (2006).
-
(2006)
Cell
, vol.126
, pp. 335-348
-
-
Reck-Peterson, S.L.1
-
34
-
-
1342325553
-
Cytoplasmic dynein functions as a gear in response to load
-
Mallik, R., Carter, B. C., Lex, S. A., King, S. J. & Gross, S. P. Cytoplasmic dynein functions as a gear in response to load. Nature 427, 649-652 (2004).
-
(2004)
Nature
, vol.427
, pp. 649-652
-
-
Mallik, R.1
Carter, B.C.2
Lex, S.A.3
King, S.J.4
Gross, S.P.5
-
35
-
-
69949115962
-
CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport
-
Lomakin, A. J. et al. CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport. Dev. Cell 17, 323-333 (2009).
-
(2009)
Dev. Cell
, vol.17
, pp. 323-333
-
-
Lomakin, A.J.1
-
36
-
-
77955303163
-
Multiple color single molecule TIRF imaging and tracking of MAPs and motors
-
Ross, J. L. & Dixit, R. Multiple color single molecule TIRF imaging and tracking of MAPs and motors. Methods. Cell Biol. 95, 521-542 (2010).
-
(2010)
Methods. Cell Biol.
, vol.95
, pp. 521-542
-
-
Ross, J.L.1
Dixit, R.2
-
37
-
-
84863465158
-
Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections
-
Schroeder, H.W. 3rd et al. Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections. Biophys. J. 103, 48-58 (2012).
-
(2012)
Biophys. J.
, vol.103
, pp. 48-58
-
-
Schroeder, H.W.1
-
38
-
-
84862520770
-
Fiji: An open-source platform for biological-image analysis
-
Schindelin, J. et al. Fiji: an open-source platform for biological-image analysis. Nat. Methods 9, 676-682 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 676-682
-
-
Schindelin, J.1
|