Silicon nanostructures for cancer diagnosis and therapy

Nanomedicine

Volumn 10, Issue 13, 2015, Pages 2109-2123

  Peng, Fei ^a   Cao, Zhaohui ^a   Ji, Xiaoyuan ^a   Chu, Binbin ^a   Su, Yuanyuan ^a   He, Yao ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

cancer diagnosis and therapy; chemotherapy; field effect transistors; hyperthermia agents; nanocarriers; phototherapy; porous silicon; silicon nanostructures; silicon nanowires; surface enhanced Raman scattering

Indexed keywords

ATORVASTATIN; CARBON NANOTUBE; CELECOXIB; DAUNORUBICIN; DOXORUBICIN; GRAPHENE; INDOMETACIN; NANOCARRIER; NANOMATERIAL; NANOPARTICLE; NANOWIRE; PACLITAXEL; QUANTUM DOT; SILICON; TUMOR MARKER; VINCRISTINE; DRUG CARRIER;

BIOSENSOR; CANCER DIAGNOSIS; CANCER THERAPY; DRUG DELIVERY SYSTEM; EARLY DIAGNOSIS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NANOBIOTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEMICONDUCTOR; ANIMAL; CHEMISTRY; DEVICES; EQUIPMENT DESIGN; GENETIC PROCEDURES; NANOMEDICINE; NEOPLASMS; PROCEDURES;

ANIMALS; BIOSENSING TECHNIQUES; DRUG CARRIERS; EQUIPMENT DESIGN; HUMANS; NANOMEDICINE; NANOSTRUCTURES; NEOPLASMS; SILICON;

EID: 84937469101     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.53     Document Type: Review

References (83)

1. He Y, Su YY. Silicon Nano-biotechnology. Springer, Berlin, Germany (2014).
2. Ji SR, Liu C, Zhang B et al. Carbon nanotubes in cancer diagnosis and therapy. BBA-Rev. Cancer 1806(1), 29-35 (2010).
3. Lee DE, Koo H, Sun IC, Ryu JH, Kim K, Kwon IC. Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem. Soc. Rev. 41(7), 2656-2672 (2012).
4. Li Z, Barnes JC, Bosoy A, Stoddart JF, Zink JI. Mesoporous silica nanoparticles in biomedical applications. Chem. Soc. Rev. 41(7), 2590-2605 (2012).
5. Peng F, Su Y, Zhong Y, Fan C, Lee S-T, He Y. Silicon nanomaterials platform for bioimaging, biosensing, and cancer therapy. Acc. Chem. Res. 47(2), 612-623 (2014).
6. Zhong Y, Peng F, Bao F et al. Large-scale aqueous synthesis of fluorescent and biocompatible silicon nanoparticles and their use as highly photostable biological probes. J. Am. Chem. Soc. 135(22), 8350-8356 (2013).
7. He Y, Su S, Xu T et al. Silicon nanowires-based highlyefficient SERS-active platform for ultrasensitive DNA detection. Nano Today 6(2), 122-130 (2011).
8. Bonanno LM, Segal E. Nanostructured porous siliconpolymer-based hybrids: from biosensing to drug delivery. Nanomedicine 6(10), 1755-1770 (2011).
9. Barnes TJ, Jarvis KL, Prestidge CA. Recent advances in porous silicon technology for drug delivery. Ther. Deliv. 4(7), 811-823 (2013).
10. Cheng X, Lowe SB, Reece PJ, Gooding JJ. Colloidal silicon quantum dots: from preparation to the modification of selfassembled monolayers (SAMs) for bio-applications. Chem. Soc. Rev. 43(8), 2680-2700 (2014).
11. McVey BFP, Tilley RD. Solution synthesis, optical properties, and bioimaging applications of silicon nanocrystals. Acc. Chem. Res. 47(10), 3045-3051 (2014).
12. Howes PD, Chandrawati R, Stevens MM. Colloidal nanoparticles as advanced biological sensors. Science 346(6205), 1247390 (2014).
13. Peng F, Su Y, Wei X et al. Silicon-nanowire-based nanocarriers with ultrahigh drug-loading capacity for in vitro and in vivo cancer therapy. Angew. Chem. Int. Ed. Engl. 52(5), 1457-1461 (2013).
14. Jiang K, Coffer JL, Gillen JG, Brewer TM. Incorporation of cesium borocaptate onto silicon nanowires as a delivery vehicle for boron neutron capture therapy. Chem. Mater. 22(2), 279-281 (2009).
15. Gu L, Hall DJ, Qin Z et al. In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles. Nat. Commun. 4, 2326 (2013).
16. Park JH, Gu L, Von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nat. Mater. 8(4), 331-336 (2009).
17. Santos HA, Mäkilä E, Airaksinen AJ, Bimbo LM, Hirvonen J. Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications. Nanomedicine 9(4), 535-554 (2014).
18. Wang HY, Jiang XX, Lee ST, He Y. Silicon nanohybridsbased surface-enhanced Raman scattering sensors. Small 10(22), 4455-4468 (2014).
19. Ji XY, Peng F, Zhong YL et al. Highly fluorescent, photostable, and ultrasmall silicon drug nanocarriers for long-term tumor cell tracking and in vivo cancer therapy. Adv. Mater. 27(6), 1029-1034 (2015).
20. Wang H, Jiang X, Wang X et al. A hairpin DNA-assisted silicon/silver-based surface-enhanced Raman scattering sensing platform for ultrahighly sensitive and specific discrimination of deafness mutations in a real system. Anal. Chem. 86(15), 7368-7376 (2014).
21. Wei X, Su S, Guo Y et al. A molecular beacon-based signaloff surface-enhanced Raman scattering strategy for highly sensitive, reproducible, and multiplexed DNA detection. Small 9(15), 2493-2499 (2013).
22. Xie J, Jiang X, Zhong Y et al. Stem-loop DNA-assisted silicon nanowires-based biochemical sensors with ultrahigh sensitivity, specificity, and multiplexing capability. Nanoscale 6(15), 9215-9222 (2014).
23. Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat. Biotechnol. 23(10), 1294-1301 (2005).
24. Peng F, Su Y, Ji X, Zhong Y, Wei X, He Y. Doxorubicinloaded silicon nanowires for the treatment of drug-resistant cancer cells. Biomaterials 35(19), 5188-5195 (2014).
25. Su Y, Wei X, Peng F et al. Gold nanoparticles-decorated silicon nanowires as highly efficient near-infrared hyperthermia agents for cancer cells destruction. Nano Lett. 12(4), 1845-1850 (2012).
26. Park GS, Kwon H, Kwak DW et al. Full surface embedding of gold clusters on silicon nanowires for efficient capture and photothermal therapy of crculating tumor cells. Nano Lett. 12(3), 1638-1642 (2012).
27. Su Y, Peng F, Ji X et al. Silicon nanowire-based therapeutic agents for in vivo tumor near-infrared photothermal ablation. J. Mater. Chem. B 2(19), 2892-2898 (2014).
28. Lee C, Kim H, Hong C et al. Porous silicon as an agent for cancer thermotherapy based on near-infrared light irradiation. J. Mater. Chem. 18(40), 4790-4795 (2008).
29. Shen H, You J, Zhang G et al. Cooperative, nanoparticleenabled thermal therapy of breast cancer. Adv. Health Mater. 1(1), 84-89 (2012).
30. Shahbazi M-A, Almeida PV, Mäkilä EM et al. Augmented cellular trafficking and endosomal escape of porous silicon nanoparticles via zwitterionic bilayer polymer surface engineering. Biomaterials 35(26), 7488-7500 (2014).
31. Liu D, Zhang H, Herranz-Blanco B et al. Microfluidic assembly of monodisperse multistage pH-responsive polymer/porous silicon composites for precisely controlled multi-drug delivery. Small 10(10), 2029-2038 (2014).
32. Yang K, Feng LZ, Shi XZ, Liu Z. Nano-graphene in biomedicine: theranostic applications. Chem. Soc. Rev. 42(2), 530-547 (2013).
33. Chen H, Zhen Z, Todd T, Chu PK, Xie J. Nanoparticles for improving cancer diagnosis. Mat. Sci. Eng. R 74(3), 35-69 (2013).
34. Blasiak B, Van Veggel FC, Tomanek B. Applications of nanoparticles for MRI cancer diagnosis and therapy. J. Nanomater. 2013, 12 (2013).
35. Bailey VJ, Keeley BP, Razavi CR, Griffiths E, Carraway HE, Wang TH. DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay. Methods 52(3), 237-241 (2010).
36. Hu M, Yan J, He Y et al. Ultrasensitive, multiplexed detection of cancer biomarkers directly in serum by using a quantum dot-based microfluidic protein chip. ACS Nano 4(1), 488-494 (2009).
37. Li N, Chang C, Pan W, Tang B. A multicolor nanoprobe for detection and imaging of tumor-related mRNAs in living cells. Angew. Chem. Int. Ed. Engl. 51(30), 7426-7430 (2012).
38. Myung S, Solanki A, Kim C, Park J, Kim KS, Lee KB. Graphene-encapsulated nanoparticle-based biosensor for the selective detection of cancer biomarkers. Adv. Mater. 23(19), 2221-2225 (2011).
39. Lerner MB, D'souza J, Pazina T et al. Hybrids of a genetically engineered antibody and a carbon nanotube transistor for detection of prostate cancer biomarkers. ACS Nano 6(6), 5143-5149 (2012).
40. Zheng G, Gao XP, Lieber CM. Frequency domain detection of biomolecules using silicon nanowire biosensors. Nano Lett. 10(8), 3179-3183 (2010).
41. Duan X, Rajan NK, Izadi MH, Reed MA. Complementary metal oxide semiconductor-compatible silicon nanowire biofield-effect transistors as affinity biosensors. Nanomedicine 8(11), 1839-1851 (2013).
42. Cui Y, Wei Q, Park H, Lieber CM. Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species. Science 293(5533), 1289-1292 (2001).
43. Lee HS, Kim KS, Kim CJ, Hahn SK, Jo MH. Electrical detection of VEGFs for cancer diagnoses using anti-vascular endotherial growth factor aptamer-modified Si nanowire FETs. Biosens. Bioelectron. 24(6), 1801-1805 (2009).
44. Stern E, Vacic A, Rajan NK et al. Label-free biomarker detection from whole blood. Nat. Nanotechnol. 5(2), 138-142 (2010).
45. Zhang GJ, Chua JH, Chee RE, Agarwal A, Wong SM. Label-free direct detection of miRNAs with silicon nanowire biosensors. Biosens. Bioelectron. 24(8), 2504-2508 (2009).
46. Shehada N, Brönstrup G, Funka K, Christiansen S, Leja M, Haick H. Ultrasensitive silicon nanowire for real-world gas sensing: noninvasive diagnosis of cancer from breath volatolome. Nano Lett. 15(2), 1288-1295 (2014).
47. Calin GA, Croce CM. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res. 66(15), 7390-7394 (2006).
48. Su S, Wei X, Zhong Y et al. Silicon nanowire-based molecular beacons for high-sensitivity and sequence-specific DNA multiplexed analysis. ACS Nano 6(3), 2582-2590 (2012).
49. Jiang ZY, Jiang XX, Su S, Wei XP, Lee ST, He Y. Siliconbased reproducible and active surface-enhanced Raman scattering substrates for sensitive, specific, and multiplex DNA detection. Appl. Phys. Lett. 100(20), 203104 (2012).
50. Jiang XX, Jiang ZY, Xu TT et al. Surface-enhanced Raman scattering-based sensing in vitro: facile and label-free detection of apoptotic cells at the single-cell level. Anal. Chem. 85(5), 2809-2816 (2013).
51. Liu H, Li Y, Sun K et al. Dual-responsive surfaces modified with phenylboronic acid-containing polymer brush to reversibly capture and release cancer cells. J. Am. Chem. Soc. 135(20), 7603-7609 (2013).
52. Shen Q, Xu L, Zhao L et al. Specific capture and release of circulating tumor cells using aptamer-modified nanosubstrates. Adv. Mater. 25(16), 2368-2373 (2013).
53. Hou S, Zhao H, Zhao L et al. Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures. Adv. Mater. 25(11), 1547-1551 (2013).
54. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2(12), 751-760 (2007).
55. Huang X, El-Sayed IH, Qian W, El-Sayed MA. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J. Am. Chem. Soc. 128(6), 2115-2120 (2006).
56. Naito K, Tachikawa T, Cui SC, Sugimoto A, Fujitsuka M, Majima T. Single-molecule detection of airborne singlet oxygen. J. Am. Chem. Soc. 128(51), 16430-16431 (2006).
57. Xiao L, Gu L, Howell SB, Sailor MJ. Porous silicon nanoparticle photosensitizers for singlet oxygen and their phototoxicity against cancer cells. ACS Nano 5(5), 3651-3659 (2011).
58. Bakalova R, Ohba H, Zhelev Z, Ishikawa M, Baba Y. Quantum dots as photosensitizers? Nat. Biotechnol. 22(11), 1360-1361 (2004).
59. Canham LT. Silicon quantum wire array fabrication by electrochemical and chemical dissolution of wafers. Appl. Phys. Lett. 57(10), 1046-1048 (1990).
60. Canham LT. Bioactive silicon structure fabrication through nanoetching techniques. Adv. Mater. 7(12), 1033-1037 (1995).
61. Fan D, Akkaraju GR, Couch EF, Canham LT, Coffer JL. The role of nanostructured mesoporous silicon in discriminating in vitro calcification for electrospun composite tissue engineering scaffolds. Nanoscale 3(2), 354-361 (2011).
62. Kashanian S, Harding F, Irani Y et al. Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implants. Acta Biomater. 6(9), 3566-3572 (2010).
63. Guan B, Magenau A, Ciampi S, Gaus K, Reece PJ, Gooding JJ. Antibody modified porous silicon microparticles for the selective capture of cells. Bioconjug. Chem. 25(7), 1282-1289 (2014).
64. Foraker A, Walczak R, Cohen M, Boiarski T, Grove C, Swaan P. Microfabricated porous silicon particles enhance paracellular delivery of insulin across intestinal Caco-2 cell monolayers. Pharm. Res. 20(1), 110-116 (2003).
65. Nan K, Ma F, Hou H, Freeman WR, Sailor MJ, Cheng L. Porous silicon oxide-PLGA composite microspheres for sustained ocular delivery of daunorubicin. Acta Biomater. 10(8), 3505-3512 (2014).
66. Liu D, Bimbo LM, Mäkilä E et al. Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles. J. Control. Release 170(2), 268-278 (2013).
67. Wang CF, Mäkilä EM, Kaasalainen MH et al. Copperfree azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake. Biomaterials 35(4), 1257-1266 (2014).
68. Vaccari L, Canton D, Zaffaroni N, Villa R, Tormen M, di Fabrizio E. Porous silicon as drug carrier for controlled delivery of doxorubicin anticancer agent. Microelectron. Eng. 83(4-9), 1598-1601 (2006).
69. Zhang M, Xu R, Xia X et al. Polycation-functionalized nanoporous silicon particles for gene silencing on breast cancer cells. Biomaterials 35(1), 423-431 (2014).
70. Yokoi K, Godin B, Oborn CJ et al. Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers. Cancer Lett. 334(2), 319-327 (2013).
71. Shrestha N, Shahbazi MA, Araújo F et al. Chitosan-modified porous silicon microparticles for enhanced permeability of insulin across intestinal cell monolayers. Biomaterials 35(25), 7172-7179 (2014).
72. Araújo F, Shrestha N, Shahbazi M-A et al. The impact of nanoparticles on the mucosal translocation and transport of GLP-1 across the intestinal epithelium. Biomaterials 35(33), 9199-9207 (2014).
73. Almeida PV, Shahbazi MA, Makila E et al. Amine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors. Nanoscale 6(17), 10377-10387 (2014).
74. Hou H, Nieto A, Ma F, Freeman WR, Sailor MJ, Cheng L. Tunable sustained intravitreal drug delivery system for daunorubicin using oxidized porous silicon. J. Control. Release 178(28), 46-54 (2014).
75. Tölli MA, Ferreira MPA, Kinnunen SM et al. In vivo biocompatibility of porous silicon biomaterials for drug delivery to the heart. Biomaterials 35(29), 8394-8405 (2014).
76. Tzur-Balter A, Gilert A, Massad-Ivanir N, Segal E. Engineering porous silicon nanostructures as tunable carriers for mitoxantrone dihydrochloride. Acta Biomater. 9(4), 6208-6217 (2013).
77. Mann AP, Tanaka T, Somasunderam A, Liu X, Gorenstein DG, Ferrari M. E-selectin-targeted porous silicon particle for nanoparticle delivery to the bone marrow. Adv. Mater. 23(36), H278-H282 (2011).
78. McInnes SJP, Irani Y, Williams KA, Voelcker NH. Controlled drug delivery from composites of nanostructured porous silicon and poly(l-lactide). Nanomedicine 7(7), 995-1016 (2012).
79. Kaasalainen M, Mäkilä E, Riikonen J et al. Effect of isotonic solutions and peptide adsorption on zeta potential of porous silicon nanoparticle drug delivery formulations. Int. J. Pharm. 431(1-2), 230-236 (2012).
80. Tasciotti E, Liu X, Bhavane R et al. Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications. Nat. Nanotechnol. 3(3), 151-157 (2008).
81. Brammer KS, Choi C, Oh S et al. Antibiofouling, sustained antibiotic release by Si nanowire templates. Nano Lett. 9(10), 3570-3574 (2009).
82. Uskokovi? V, Lee K, Lee PP, Fischer KE, Desai TA. Shape effect in the design of nanowire-coated microparticles as transepithelial drug delivery devices. ACS Nano 6(9), 7832-7841 (2012).
83. Kim W, Ng JK, Kunitake ME, Conklin BR, Yang P. Interfacing silicon nanowires with mammalian cells. J. Am. Chem. Soc. 129(23), 7228-7229 (2007).