Shape effect in the design of nanowire-coated microparticles as transepithelial drug delivery devices

ACS Nano

Volumn 6, Issue 9, 2012, Pages 7832-7841

  Uskoković, Vuk ^a   Lee, Kunwoo ^a,b   Lee, Phin Peng ^a   Fischer, Kathleen E ^a   Desai, Tejal A ^a  

^a San Francisco   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Caco 2; epithelium; insulin; nanowire; oral drug delivery

Indexed keywords

CACO-2; CACO-2 CELLS; COMPOSITE PARTICLES; CONSTANT RELEASE; CUMULATIVE AMOUNT; DRUG CARRIER; DRUG DELIVERY DEVICES; DRUG-LOADING EFFICIENCY; ELUTION PROFILES; EPITHELIAL CELLS; EPITHELIUM; IMMUNOHISTOCHEMICAL STUDIES; IN-VITRO; MICRO-PARTICLES; MICROVILLI; MODEL DRUGS; ORAL DELIVERY; ORAL DRUG DELIVERY; PARTICLE MORPHOLOGIES; PLANAR SILICA; SHAPE EFFECT; SILICA BEADS; SILICON WIRES; SMALL ORGANIC MOLECULES; SPHERICAL PARTICLE; SURFACE AREA; THERAPEUTIC COMPOUNDS; TIGHT JUNCTIONS; TRANSEPITHELIAL PERMEABILITY;

BIOCHEMISTRY; CELLS; COATING TECHNIQUES; DRUG DELIVERY; INSULIN; MOLECULES; MONOLAYERS; SILICA;

NANOWIRES;

INSULIN; NANOCAPSULE;

ANIMAL; ARTICLE; BLOOD; CELL STRAIN CACO 2; CHEMISTRY; EPITHELIUM CELL; HUMAN; MATERIALS TESTING; METABOLISM; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; RABBIT; ULTRASTRUCTURE;

ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; EPITHELIAL CELLS; HUMANS; INSULIN; MATERIALS TESTING; NANOCAPSULES; PARTICLE SIZE; RABBITS;

EID: 84866713672     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn3019865     Document Type: Article

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