Microfabricated porous silicon particles enhance paracellular delivery of insulin across intestinal caco-2 cell monolayers

Pharmaceutical Research

Volumn 20, Issue 1, 2003, Pages 110-116

  Foraker, Amy B ^a   Walczak, Rob J ^b   Cohen, Michael H ^b   Boiarski, Tony A ^b   Grove, Carl F ^b   Swaan, Peter W ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b IMEDD Inc   (United States)

Author keywords

Insulin; Nanoparticles; Paracellular transport; Permeation enhancer; Sodium caprate; Sodium laurate; Tight junction

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; INSULIN; LAURATE SODIUM; LAURIC ACID DERIVATIVE; SILICON DERIVATIVE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; DRUG TRANSPORT; GEL ELECTROPHORESIS; HORMONE TRANSPORT; HUMAN; HUMAN CELL; INTESTINE CELL; LIQUID; MONOLAYER CULTURE; PRIORITY JOURNAL; TRANSCYTOSIS;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DRUG DELIVERY SYSTEMS; HUMANS; INSULIN; POROSITY; RATS; SILICON; TECHNOLOGY, PHARMACEUTICAL;

EID: 0037255435     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022211127890     Document Type: Article

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