Notch1-STAT3-ETBR signaling axis controls reactive astrocyte proliferation after brain injury

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 28, 2015, Pages 8726-8731

  LeComte, Matthew D ^a,b   Shimada, Issei S ^a,c   Sherwin, Casey ^a,b   Spees, Jeffrey L ^a,b  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

ETbR; Notch1; Proliferation; Reactive astrocyte; STAT3

Indexed keywords

ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR TYPE B; JAGGED1; NOTCH1 RECEPTOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; ENDOTHELIN B RECEPTOR; NOTCH1 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BRAIN INJURY; C57BL MOUSE; CELL PROLIFERATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; PROMOTER REGION;

MUS;

ANIMALS; ASTROCYTES; BRAIN INJURIES; CELL PROLIFERATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; RECEPTOR, ENDOTHELIN B; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84937249994     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501029112     Document Type: Article

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