5-Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8-oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X-ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts

Journal of Organic Chemistry

Volumn 80, Issue 14, 2015, Pages 6996-7007

  Alshykhly, Omar R ^a   Fleming, Aaron M ^a   Burrows, Cynthia J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; DNA; POSITIVE IONS; RADIATION CHEMISTRY;

8-OXO-7 ,8-DIHYDROGUANINE; CHEMICAL EQUATIONS; DEOXYGUANOSINE (DG); OLIGODEOXYNUCLEOTIDES; RADIOLYSIS OF WATERS; REACTIVE OXYGEN SPECIES; REDUCING CONDITIONS; SPIROIMINODIHYDANTOIN;

OXIDATION;

8 HYDROXYGUANINE; ACETYLCYSTEINE; ASCORBIC ACID; DNA; GUANINE DERIVATIVE; GUANOSINE DERIVATIVE; HYDANTOIN DERIVATIVE; IRON; NUCLEOSIDE; OLIGODEOXYNUCLEOTIDE; OXAZOLONE; OXYGEN; WATER; 5-CARBOXAMIDO-5-FORMAMIDO-2-IMINOHYDANTOIN; 8-HYDROXYGUANINE; DEOXYGUANOSINE; GUANIDINE DERIVATIVE; GUANIDINOHYDANTOIN; GUANINE;

ARTICLE; CHEMICAL REACTION; FENTON REACTION; HYDROXYLATION; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; RADIOLYSIS; X IRRADIATION; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; OXIDATION REDUCTION REACTION; X RAY;

DEOXYGUANOSINE; DNA; GUANIDINES; GUANINE; HYDANTOINS; IRON; MOLECULAR STRUCTURE; NUCLEOSIDES; OXAZOLONE; OXIDATION-REDUCTION; OXYGEN; X-RAYS;

EID: 84937231614     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/acs.joc.5b00689     Document Type: Article

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