메뉴 건너뛰기




Volumn 122, Issue 10, 2000, Pages 2373-2374

The trap depth (in DNA) of 8-oxo-7,8-dihydro-2'deoxyguanosine as derived from electron-transfer equilibria in aqueous solution [2]

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGUANOSINE DERIVATIVE; DNA;

EID: 0034653650     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja993508e     Document Type: Letter
Times cited : (248)

References (50)
  • 2
    • 0004198354 scopus 로고
    • Academic Press: Orlando, FL
    • Sies, H. Oxidative Stress; Academic Press: Orlando, FL, 1985.
    • (1985) Oxidative Stress
    • Sies, H.1
  • 6
    • 0002738322 scopus 로고
    • Sies, H., Ed.; Academic Press: London
    • Kasai, H.; Nishimura, S. In Oxidative Stress; Sies, H., Ed.; Academic Press: London, 1991; p 99.
    • (1991) Oxidative Stress , pp. 99
    • Kasai, H.1    Nishimura, S.2
  • 7
    • 0024201717 scopus 로고
    • Simic, M. G., Taylor, K. A., Ward, J. F., von Sonntag, C., Eds.: Plenum Press: New York, London
    • Cundy, K. C.; Kohen, R.; Ames, B. N. In Oxygen Radicals in Biology and Medicine; Simic, M. G., Taylor, K. A., Ward, J. F., von Sonntag, C., Eds.: Plenum Press: New York, London, 1988; Vol. 49, p 479.
    • (1988) Oxygen Radicals in Biology and Medicine , vol.49 , pp. 479
    • Cundy, K.C.1    Kohen, R.2    Ames, B.N.3
  • 8
    • 0024240653 scopus 로고
    • Simic, M. G., Taylor, K. A., Ward, J. F., von Sonntag, C., Eds.; Plenum Press: New York, London
    • Bergtold, D. S.; Simic, M. G.; Alessio, H.; Cutler, R. G. In Oxygen Radicals in Biology and Medicine; Simic, M. G., Taylor, K. A., Ward, J. F., von Sonntag, C., Eds.; Plenum Press: New York, London, 1988; Vol. 49, p 483.
    • (1988) Oxygen Radicals in Biology and Medicine , vol.49 , pp. 483
    • Bergtold, D.S.1    Simic, M.G.2    Alessio, H.3    Cutler, R.G.4
  • 25
    • 0000579871 scopus 로고
    • Morrison, H., Ed.; Wiley and Sons: New York
    • Kochevar, I. E.; Dunn, D. A. In Bioorganic Photochemistry; Morrison, H., Ed.; Wiley and Sons: New York, 1990; Vol. 1, p 273.
    • (1990) Bioorganic Photochemistry , vol.1 , pp. 273
    • Kochevar, I.E.1    Dunn, D.A.2
  • 28
    • 0343156930 scopus 로고    scopus 로고
    • From Berry Co., Dexter, MI, purity "100%" (HPLC)
    • From Berry Co., Dexter, MI, purity "100%" (HPLC).
  • 29
    • 0343156929 scopus 로고    scopus 로고
    • The spectra of oxidized 8-OHdGuo at pH 3, 7.7, and 13.3 are available in Supporting Information
    • The spectra of oxidized 8-OHdGuo at pH 3, 7.7, and 13.3 are available in Supporting Information.
  • 30
    • 0000288179 scopus 로고
    • under the same conditions, it was established (the conductance signals had the same shape and amplitude within ±49%) that the species existing at pH < 6 is the radical cation of 8-OHdG
    • ·- at pH 4.5 to one-electron-oxidue 8-OHdG and, for calibration, anisole radical cation (O'Neill, P.; Steenken, S.; Schulte-Frohlinde, D. J. Phys. Chem. 1975, 79, 2773)) under the same conditions, it was established (the conductance signals had the same shape and amplitude within ±49%) that the species existing at pH < 6 is the radical cation of 8-OHdG.
    • (1975) J. Phys. Chem. , vol.79 , pp. 2773
    • O'Neill, P.1    Steenken, S.2    Schulte-Frohlinde, D.3
  • 33
    • 0016854447 scopus 로고
    • The reactions of enolether radical cations with the guanine moiety are relevant because enolether radical cations are formed in DNA as a result of C4′-radical initiated chain breaks (Dizdaroglu, M.; von Sonntag, C.; Schulte-Frohlinde, D. J. Am. Chem. Soc. 1975, 97, 2277; Giese, B.; Beyrich-Graf, X.; Erdmann, P.; Petretta, M.; Schwitter, U. Chem. Biol. 1995, 2, 367).
    • (1975) J. Am. Chem. Soc. , vol.97 , pp. 2277
    • Dizdaroglu, M.1    Von Sonntag, C.2    Schulte-Frohlinde, D.3
  • 34
    • 0029310521 scopus 로고
    • The reactions of enolether radical cations with the guanine moiety are relevant because enolether radical cations are formed in DNA as a result of C4′-radical initiated chain breaks (Dizdaroglu, M.; von Sonntag, C.; Schulte- Frohlinde, D. J. Am. Chem. Soc. 1975, 97, 2277; Giese, B.; Beyrich-Graf, X.; Erdmann, P.; Petretta, M.; Schwitter, U. Chem. Biol. 1995, 2, 367).
    • (1995) Chem. Biol. , vol.2 , pp. 367
    • Giese, B.1    Beyrich-Graf, X.2    Erdmann, P.3    Petretta, M.4    Schwitter, U.5
  • 39
    • 0342722465 scopus 로고    scopus 로고
    • note
    • 4 as electrolyte. The (reversible) value was found to be independent of pH in the range 1-12. We thank Dr. E. Bothe for performing this experiment.
  • 42
    • 0343156921 scopus 로고    scopus 로고
    • note
    • 0, results as 1.18 V/NHE taking into account the three different protonation states of the 8-OHdG radical shown in Scheme 1.
  • 43
    • 0342287368 scopus 로고    scopus 로고
    • note
    • The difference in the (irreversible) "half peak" potentials in DMF has been measured to be 0.43 V (ref 14).
  • 44
    • 0343592417 scopus 로고    scopus 로고
    • As shown in ref 26, stacking of 8-OHdG with G does not change the relative potential of G and 8-OHdG moieties
    • As shown in ref 26, stacking of 8-OHdG with G does not change the relative potential of G and 8-OHdG moieties.
  • 45
    • 0343592416 scopus 로고    scopus 로고
    • note
    • Although the redox potentials of the bases in the DNA polymer are not known, it is likely that the change from aqueous to "DNA phase" or stacking interactions (ref 26) do not change the relative potentials.
  • 46
    • 0342722460 scopus 로고    scopus 로고
    • note
    • Similar ideas have been put foreward previously (refs 14, 21, 23-26).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.