Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: Mechanistic studies with 18O

Chemical Research in Toxicology

Volumn 17, Issue 11, 2004, Pages 1510-1519

  Niles, Jacquin C ^a   Wishnok, John S ^a   Tannenbaum, Steven R ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4,6 TRIOXO[1,3,5]TRIAZINANE 1 CARBOXAMIDINE; 4 HYDROXYDIOXOIMIDAZOLIDINE 4 CARBOXYLIC ACID; 8 OXOGUANOSINE; ANION; DEHYDROGUANIDINOHYDANTOIN; GUANIDINE DERIVATIVE; GUANIDINOHYDANTOIN; GUANOSINE DERIVATIVE; HYDANTOIN DERIVATIVE; IMINE; N NITRO DEHYDROGUANIDINOHYDANTOIN; OXIDIZING AGENT; OXYGEN 18; PEROXYNITRITE; SPIRO COMPOUND; SPIROIMINODIHYDANTOIN; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ACIDITY; ALKALINITY; ARTICLE; ATOM; CONCENTRATION RESPONSE; OXIDATION; PKA; PROTON TRANSPORT; REACTION ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GUANIDINES; GUANOSINE; MODELS, CHEMICAL; NITRATES; OXIDATION-REDUCTION; OXYGEN ISOTOPES; SPIRO COMPOUNDS;

EID: 8844267545     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0400048     Document Type: Article

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