메뉴 건너뛰기




Volumn 1, Issue 7, 2014, Pages 540-555

Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells

Author keywords

Cell cycle; DNA crosslinks; DNA fiber analysis; DNA replication; Fanconi Anemia protein D2; Mitomycin C; S phase

Indexed keywords


EID: 84937214348     PISSN: None     EISSN: 23314737     Source Type: Journal    
DOI: 10.18632/oncoscience.70     Document Type: Article
Times cited : (10)

References (52)
  • 1
    • 79959635260 scopus 로고    scopus 로고
    • DNA interstrand crosslink repair and cancer
    • Deans AJ and West SC. DNA interstrand crosslink repair and cancer. Nat Rev Cancer. 2011; 11(7): 467-480.
    • (2011) Nat Rev Cancer , vol.11 , Issue.7 , pp. 467-480
    • Deans, A.J.1    West, S.C.2
  • 3
    • 69749106825 scopus 로고    scopus 로고
    • Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication
    • Shen X, Do H, Li Y, Chung W-H, Tomasz M, de Winter JP, Xia B, Elledge SJ, Wang W and Li L. Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication. Molecular Cell. 2009; 35(5): 716-723.
    • (2009) Molecular Cell , vol.35 , Issue.5 , pp. 716-723
    • Shen, X.1    Do, H.2    Li, Y.3    Chung, W.-H.4    Tomasz, M.5    de Winter, J.P.6    Xia, B.7    Elledge, S.J.8    Wang, W.9    Li, L.10
  • 6
    • 77955869859 scopus 로고    scopus 로고
    • Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle
    • Legerski RJ. Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle. Environmental and Molecular Mutagenesis. 2010; 51(6): 540-551.
    • (2010) Environmental and Molecular Mutagenesis , vol.51 , Issue.6 , pp. 540-551
    • Legerski, R.J.1
  • 7
    • 84859747536 scopus 로고    scopus 로고
    • Rescue of replication failure by Fanconi anaemia proteins
    • Constantinou A. Rescue of replication failure by Fanconi anaemia proteins. Chromosoma. 2012; 121(1): 21-36.
    • (2012) Chromosoma , vol.121 , Issue.1 , pp. 21-36
    • Constantinou, A.1
  • 12
    • 84863670930 scopus 로고    scopus 로고
    • Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
    • Kim H and D'Andrea AD. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes & Development. 2012; 26(13): 1393-1408.
    • (2012) Genes & Development , vol.26 , Issue.13 , pp. 1393-1408
    • Kim, H.1    D'Andrea, A.D.2
  • 13
    • 84872578210 scopus 로고    scopus 로고
    • Fanconi anaemia and the repair of Watson and Crick DNA crosslinks
    • Kottemann MC and Smogorzewska A. Fanconi anaemia and the repair of Watson and Crick DNA crosslinks. Nature. 2013; 493(7432): 356-363.
    • (2013) Nature , vol.493 , Issue.7432 , pp. 356-363
    • Kottemann, M.C.1    Smogorzewska, A.2
  • 14
    • 67349187702 scopus 로고    scopus 로고
    • The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
    • Naim V and Rosselli F. The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat Cell Biol. 2009; 11(6): 761-768.
    • (2009) Nat Cell Biol , vol.11 , Issue.6 , pp. 761-768
    • Naim, V.1    Rosselli, F.2
  • 15
    • 67349227137 scopus 로고    scopus 로고
    • Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
    • Chan KL, Palmai-Pallag T, Ying S and Hickson ID. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat Cell Biol. 2009; 11(6): 753-760.
    • (2009) Nat Cell Biol , vol.11 , Issue.6 , pp. 753-760
    • Chan, K.L.1    Palmai-Pallag, T.2    Ying, S.3    Hickson, I.D.4
  • 16
    • 77954163083 scopus 로고    scopus 로고
    • A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells
    • Song IY, Barkley LR, Day TA, Weiss RS and Vaziri C. A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells. Cell Cycle. 2010; 9(12): 2375-2388.
    • (2010) Cell Cycle , vol.9 , Issue.12 , pp. 2375-2388
    • Song, I.Y.1    Barkley, L.R.2    Day, T.A.3    Weiss, R.S.4    Vaziri, C.5
  • 17
    • 84863753191 scopus 로고    scopus 로고
    • A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
    • Schlacher K, Wu H and Jasin M. A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2. Cancer Cell. 2012; 22(1): 106-116.
    • (2012) Cancer Cell , vol.22 , Issue.1 , pp. 106-116
    • Schlacher, K.1    Wu, H.2    Jasin, M.3
  • 18
    • 84880534493 scopus 로고    scopus 로고
    • FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery
    • Chaudhury I, Sareen A, Raghunandan M and Sobeck A. FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery. Nucleic Acids Research. 2013; 41(13): 6444-6459.
    • (2013) Nucleic Acids Research , vol.41 , Issue.13 , pp. 6444-6459
    • Chaudhury, I.1    Sareen, A.2    Raghunandan, M.3    Sobeck, A.4
  • 20
    • 0037425566 scopus 로고    scopus 로고
    • NMR determination of the conformation of a trimethylene interstrand cross-link in an oligodeoxynucleotide duplex containing a 5'-d(GpC) motif
    • Dooley PA, Zhang M, Korbel GA, Nechev LV, Harris CM, Stone MP and Harris TM. NMR determination of the conformation of a trimethylene interstrand cross-link in an oligodeoxynucleotide duplex containing a 5'-d(GpC) motif. Journal of the American Chemical Society. 2003; 125(1): 62-72.
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.1 , pp. 62-72
    • Dooley, P.A.1    Zhang, M.2    Korbel, G.A.3    Nechev, L.V.4    Harris, C.M.5    Stone, M.P.6    Harris, T.M.7
  • 21
    • 77955505023 scopus 로고    scopus 로고
    • The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response
    • Huang M, Kim JM, Shiotani B, Yang K, Zou L and D'Andrea AD. The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response. Molecular Cell. 2010; 39(2): 259-268.
    • (2010) Molecular Cell , vol.39 , Issue.2 , pp. 259-268
    • Huang, M.1    Kim, J.M.2    Shiotani, B.3    Yang, K.4    Zou, L.5    D'Andrea, A.D.6
  • 22
    • 0032861343 scopus 로고    scopus 로고
    • Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo
    • Rogakou EP, Boon C, Redon C and Bonner WM. Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo. The Journal of Cell Biology. 1999; 146(5): 905-916.
    • (1999) The Journal of Cell Biology , vol.146 , Issue.5 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 24
    • 84877888161 scopus 로고    scopus 로고
    • Controlling DNA replication origins in response to DNA damage: inhibit globally, activate locally
    • Yekezare M, Gomez-Gonzalez B and Diffley JFX. Controlling DNA replication origins in response to DNA damage: inhibit globally, activate locally. Journal of Cell Science. 2013; 126(6): 1297-1306.
    • (2013) Journal of Cell Science , vol.126 , Issue.6 , pp. 1297-1306
    • Yekezare, M.1    Gomez-Gonzalez, B.2    Diffley, J.F.X.3
  • 25
    • 34547902426 scopus 로고    scopus 로고
    • The Intra-S-Phase Checkpoint Affects both DNA Replication Initiation and Elongation: Single-Cell and-DNA Fiber Analyses
    • Seiler JA, Conti C, Syed A, Aladjem MI and Pommier Y. The Intra-S-Phase Checkpoint Affects both DNA Replication Initiation and Elongation: Single-Cell and-DNA Fiber Analyses. Mol Cell Biol. 2007; 27(16): 5806-5818.
    • (2007) Mol Cell Biol , vol.27 , Issue.16 , pp. 5806-5818
    • Seiler, J.A.1    Conti, C.2    Syed, A.3    Aladjem, M.I.4    Pommier, Y.5
  • 26
    • 37249004667 scopus 로고    scopus 로고
    • The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses
    • Epub 2007 Aug 2722
    • Conti C, Seiler JA and Pommier Y. The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses. Cell Cycle. 2007; 6(22): 2760-2767. Epub 2007 Aug 2722.
    • (2007) Cell Cycle , vol.6 , Issue.22 , pp. 2760-2767
    • Conti, C.1    Seiler, J.A.2    Pommier, Y.3
  • 27
    • 34147201111 scopus 로고    scopus 로고
    • The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
    • Unsal-Kacmaz K, Chastain PD, Qu P-P, Minoo P, Cordeiro-Stone M, Sancar A and Kaufmann WK. The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement. Mol Cell Biol. 2007; 27(8): 3131-3142.
    • (2007) Mol Cell Biol , vol.27 , Issue.8 , pp. 3131-3142
    • Unsal-Kacmaz, K.1    Chastain, P.D.2    Qu, P.-P.3    Minoo, P.4    Cordeiro-Stone, M.5    Sancar, A.6    Kaufmann, W.K.7
  • 29
    • 2442582392 scopus 로고    scopus 로고
    • Visualization of Altered Replication Dynamics after DNA Damage in Human Cells
    • Merrick CJ, Jackson D and Diffley JFX. Visualization of Altered Replication Dynamics after DNA Damage in Human Cells. J Biol Chem. 2004; 279(19): 20067-20075.
    • (2004) J Biol Chem , vol.279 , Issue.19 , pp. 20067-20075
    • Merrick, C.J.1    Jackson, D.2    Diffley, J.F.X.3
  • 31
    • 34447115757 scopus 로고    scopus 로고
    • Role for BLM in replication-fork restart and suppression of origin firing after replicative stress
    • Epub 2007 Jun 2024
    • Davies SL, North PS and Hickson ID. Role for BLM in replication-fork restart and suppression of origin firing after replicative stress. Nat Struct Mol Biol. 2007; 14(7): 677-679. Epub 2007 Jun 2024.
    • (2007) Nat Struct Mol Biol , vol.14 , Issue.7 , pp. 677-679
    • Davies, S.L.1    North, P.S.2    Hickson, I.D.3
  • 32
    • 0042743766 scopus 로고    scopus 로고
    • Dynamics of DNA Replication in Mammalian Somatic Cells: Nucleotide Pool Modulates Origin Choice and Interorigin Spacing
    • Anglana M, Apiou F, Bensimon A and Debatisse M. Dynamics of DNA Replication in Mammalian Somatic Cells: Nucleotide Pool Modulates Origin Choice and Interorigin Spacing. Cell. 2003; 114(3): 385-394.
    • (2003) Cell , vol.114 , Issue.3 , pp. 385-394
    • Anglana, M.1    Apiou, F.2    Bensimon, A.3    Debatisse, M.4
  • 33
    • 78650724206 scopus 로고    scopus 로고
    • Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories
    • Ge XQ and Blow JJ. Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories. The Journal of Cell Biology. 2010; 191(7): 1285-1297.
    • (2010) The Journal of Cell Biology , vol.191 , Issue.7 , pp. 1285-1297
    • Ge, X.Q.1    Blow, J.J.2
  • 34
    • 79954600104 scopus 로고    scopus 로고
    • Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation
    • Minca EC and Kowalski D. Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation. Nucleic Acids Research. 2011; 39(7): 2610-2623.
    • (2011) Nucleic Acids Research , vol.39 , Issue.7 , pp. 2610-2623
    • Minca, E.C.1    Kowalski, D.2
  • 36
    • 84869196750 scopus 로고    scopus 로고
    • DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells
    • Vare D, Groth P, Carlsson R, Johansson F, Erixon K and Jenssen D. DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells. DNA Repair (Amst). 2012; 11(12): 976-985.
    • (2012) DNA Repair (Amst) , vol.11 , Issue.12 , pp. 976-985
    • Vare, D.1    Groth, P.2    Carlsson, R.3    Johansson, F.4    Erixon, K.5    Jenssen, D.6
  • 38
    • 77955739839 scopus 로고    scopus 로고
    • Clusters, factories and domains: The complex structure of S phase comes into focus
    • Gillespie PJ and Blow J. Clusters, factories and domains: The complex structure of S phase comes into focus. Cell Cycle. 2010; 9(16): 3238-3246.
    • (2010) Cell Cycle , vol.9 , Issue.16 , pp. 3238-3246
    • Gillespie, P.J.1    Blow, J.2
  • 39
    • 80053555789 scopus 로고    scopus 로고
    • More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
    • Lukas J, Lukas C and Bartek J. More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol. 2011; 13(10): 1161-1169.
    • (2011) Nat Cell Biol , vol.13 , Issue.10 , pp. 1161-1169
    • Lukas, J.1    Lukas, C.2    Bartek, J.3
  • 40
    • 84871344464 scopus 로고    scopus 로고
    • Chromatin and the genome integrity network
    • Papamichos-Chronakis M and Peterson CL. Chromatin and the genome integrity network. Nat Rev Genet. 2013; 14(1): 62-75.
    • (2013) Nat Rev Genet , vol.14 , Issue.1 , pp. 62-75
    • Papamichos-Chronakis, M.1    Peterson, C.L.2
  • 41
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward IM and Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. Journal of Biological Chemistry. 2001; 276(51): 47759-47762.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.51 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 46
    • 1842685207 scopus 로고    scopus 로고
    • The Werner syndrome protein has separable recombination and survival functions
    • Swanson C, Saintigny Y, Emond MJ and Monnat J, Raymond J. The Werner syndrome protein has separable recombination and survival functions. DNA Repair. 2004; 3(5): 475-482.
    • (2004) DNA Repair , vol.3 , Issue.5 , pp. 475-482
    • Swanson, C.1    Saintigny, Y.2    Emond, M.J.3    Monnat, J.4    Raymond, J.5
  • 47
    • 42049116919 scopus 로고    scopus 로고
    • The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
    • Sidorova JM, Li N, Folch A and Monnat RJ, Jr. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle. 2008; 7(6): 796-807.
    • (2008) Cell Cycle , vol.7 , Issue.6 , pp. 796-807
    • Sidorova, J.M.1    Li, N.2    Folch, A.3    Monnat, R.J.4
  • 48
    • 77955738562 scopus 로고    scopus 로고
    • The Human WRN and BLM RecQ Helicases Differentially Regulate Cell Proliferation and Survival after Chemotherapeutic DNA Damage
    • Mao FJ, Sidorova JM, Lauper JM, Emond MJ and Monnat RJ. The Human WRN and BLM RecQ Helicases Differentially Regulate Cell Proliferation and Survival after Chemotherapeutic DNA Damage. Cancer Research. 2010; 70(16): 6548-6555.
    • (2010) Cancer Research , vol.70 , Issue.16 , pp. 6548-6555
    • Mao, F.J.1    Sidorova, J.M.2    Lauper, J.M.3    Emond, M.J.4    Monnat, R.J.5
  • 49
    • 84872486501 scopus 로고    scopus 로고
    • Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyureainduced stalling
    • Sidorova JM, Kehrli K, Mao F and Monnat Jr R. Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyureainduced stalling. DNA Repair. 2013; 12(2): 128-139.
    • (2013) DNA Repair , vol.12 , Issue.2 , pp. 128-139
    • Sidorova, J.M.1    Kehrli, K.2    Mao, F.3    Monnat, R.4
  • 50
    • 84871338630 scopus 로고    scopus 로고
    • Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine-the method for the effective suppression of this cross-reactivity
    • Liboska R, Ligasova A, Strunin D, Rosenberg I and Koberna K. Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine-the method for the effective suppression of this cross-reactivity. PLoS One. 2012; 7(12): e51679.
    • (2012) PLoS One , vol.7 , Issue.12
    • Liboska, R.1    Ligasova, A.2    Strunin, D.3    Rosenberg, I.4    Koberna, K.5
  • 52
    • 84861741887 scopus 로고    scopus 로고
    • Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA
    • Sirbu BM, Couch FB and Cortez D. Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA. Nat Protocols. 2012; 7(3): 594-605.
    • (2012) Nat Protocols , vol.7 , Issue.3 , pp. 594-605
    • Sirbu, B.M.1    Couch, F.B.2    Cortez, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.